Abstract: A wireless control system usable with portable electronic device includes at least one controlled device, at least one portable electronic device, and a wireless control device. The portable electronic device is electrically connectable to the wireless control device, and has application software stored therein. The portable electronic device is capable of reading in an operating command to thereby execute the application software that corresponds to the controlled device and generate a remote-control signal. The wireless control device transmits the remote-control signal generated by the portable electronic device to the controlled device for the latter to execute an operation in response to the received remote-control signal. With the above arrangements, the wireless control system is very convenient for use.