Patents by Inventor Kuei-Tien Chen

Kuei-Tien Chen has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Serological markers for detecting colorectal cancer and their application for inhibiting colorectal cancer cells
    Patent number: 9835636
    Abstract: Embodiments relate to serological markers for detecting the colorectal cancer and applications of the serological markers. A phospholipid scramblase1 (PLSCR1), a stomatin-like protein 2 (STOML2) or a transport protein Sec61? (SEC61?) increases expression in the blood at the earlier stage of the colorectal cancer. Detecting the expression of the PLSCR1, STOML2 or SEC61? protein or an induced autoantibody of each protein in a blood sample is used to diagnose the colorectal cancer. Moreover, the serological marker improves the detection efficiency and the sensitivity in detecting the colorectal cancer and is used to predict the prognosis. The serological markers are applied in preparing a detection device or inhibiting the growth of the colorectal cancer cells.
    Type: Grant
    Filed: May 10, 2013
    Date of Patent: December 5, 2017
    Assignee: CHANG GUNG UNIVERSITY
    Inventors: Err-Cheng Chan, Kuei-Tien Chen, Jau-Song Yu, Yu-Sun Chang, Jinn-Shiun Chen
  • Method of PLSCR inhibition for cancer therapy
    Patent number: 8691229
    Abstract: The present invention relates to a method of using inhibitors of phospholipid scramblases (PLSCRs) for the prophylactic or therapeutic treatment of cancers. The PLSCR-inhibitors of the invention comprise compounds PLSCR-specific monoclonal antibodies, antagonists or nucleic acids, which have ability to decrease the level and/or biological activity of PLSCRs in cancer cells.
    Type: Grant
    Filed: April 20, 2012
    Date of Patent: April 8, 2014
    Assignee: Err-Cheng CHAN
    Inventors: Err-Cheng Chan, Hong-Arh Fan, Kuei-Tien Chen, Yung-Bin Kuo, Jinn-Shiun Chen, Chung-Wei Fan
  • METHOD OF PLSCR INHIBITION FOR CANCER THERAPY
    Publication number: 20130280242
    Abstract: The present invention relates to a method of using inhibitors of phospholipid scramblases (PLSCRs) for the prophylactic or therapeutic treatment of cancers. The PLSCR-inhibitors of the invention comprise compounds PLSCR-specific monoclonal antibodies, antagonists or nucleic acids, which have ability to decrease the level and/or biological activity of PLSCRs in cancer cells.
    Type: Application
    Filed: April 20, 2012
    Publication date: October 24, 2013
    Inventors: Err-Cheng CHAN, Hong-Arh FAN, Kuei-Tien Chen, Yung-Bin Kuo, Jinn Shiun Chen, Chung-Wei Fan
  • SEROLOGICAL MARKERS FOR DETECTING COLORECTAL CANCER AND THEIR APPLICATION FOR INHIBITING COLORECTAL CANCER CELLS
    Publication number: 20130236913
    Abstract: Embodiments relate to serological markers for detecting the colorectal cancer and applications of the serological markers. A phospholipid scramblase (PLSCR1), a stomatin-like protein 2 (STOML2) or a transport protein Sec61? (SEC61?) increases expression in the blood at the earlier stage of the colorectal cancer. Detecting the expression of the PLSCR1, STOML2 or SEC61? protein or an induced autoantibody of each protein in a blood sample is used to diagnose the colorectal cancer. Moreover, the serological marker improves the detection efficiency and the sensitivity in detecting the colorectal cancer and is used to predict the prognosis. The serological markers are applied in preparing a detection device or inhibiting the growth of the colorectal cancer cells.
    Type: Application
    Filed: May 10, 2013
    Publication date: September 12, 2013
    Applicant: CHANG GUNG UNIVERSITY
    Inventors: Err-Cheng CHAN, Kuei-Tien CHEN, Jau-Song YU, Yu-Sun CHANG, Jinn-Shiun CHEN
  • SEROLOGICAL MARKERS FOR DETECTING COLORECTAL CANCER AND THEIR APPLICATION FOR INHIBITING COLORECTAL CANCER CELLS
    Publication number: 20130084582
    Abstract: Embodiments relate to serological markers for detecting the colorectal cancer and applications of the serological markers. A phospholipid scramblase1 (PLSCR1), a stomatin-like protein 2 (STOML2) or a transport protein Sec61? (SEC61?) increases expression in the blood at the earlier stage of the colorectal cancer. Detecting the expression of the PLSCR1, STOML2 or SEC61? protein or an induced autoantibody of each protein in a blood sample is used to diagnose the colorectal cancer. Moreover, the serological marker improves the detection efficiency and the sensitivity in detecting the colorectal cancer and is used to predict the prognosis. The serological markers are applied in preparing a detection device or inhibiting the growth of the colorectal cancer cells.
    Type: Application
    Filed: October 4, 2011
    Publication date: April 4, 2013
    Inventors: Err-Cheng Chan, Kuei-Tien Chen, Jau-Song Yu, Yu-Sun Chang, Jinn-Shiun Chen