Abstract: A spatial omics single cell data acquisition method includes: acquiring a dyeing image of a biological sample, and acquiring a visual gene expression image of the biological sample; registering the dyeing image with the visual gene expression image, so as to obtain a registered image; performing cell segmentation on the registered image, so as to obtain a cell mask image; and according to the cell mask image, determining a cell of a background gene molecule of an unknown cell in the visual gene expression image, and marking the cell, so as to obtain a spatial omics molecular expression matrix with a cell mark. Compared with the prior art, the present disclosure relates to obtaining high-precision spatial single cell data by means of a gene expression matrix diagram, and a processing flow involving splicing, registration, segmentation and correction.

Abstract: A method for stitching a first image and a second image. The method includes determining an overlapping region of the first image and the second image; respectively cropping a part, determined as the overlapping region, of the first image and the second image into a plurality of first image overlapping sub-images and a plurality of second image overlapping sub-images of a same number for pairing into a plurality of overlapping sub-image pairs; obtaining an offset between the first image and the second image by performing frequency domain calculation on the plurality of overlapping sub-image pairs; and translating the first image toward a direction of the second image by the offset, and stitching the first image and the second image.

Abstract: The invention relates to human cytokine polypeptides, polynucleotides encoding the polypeptides, methods for producing the polypeptides, in particular by expressing the polynucleotides, and agonists and antagonists of the polypeptides. The invention further relates to methods for utilizing such polynucleotides, polypeptides, agonists and antagonists for applications, which relate, in part, to research, diagnostic and clinical arts.

Abstract: The invention relates to human cytokine polypeptides, polynucleotides encoding the polypeptides, methods for producing the polypeptides, in particular by expressing the polynucleotides, and agonists and antagonists of the polypeptides. The invention further relates to methods for utilizing such polynucleotides, polypeptides, agonists and antagonists for applications, which relate, in part, to research, diagnostic and clinical arts.