Patents by Inventor Kuifeng WANG

Kuifeng WANG has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Pyrazine derivative and application thereof in inhibiting SHP2
    Patent number: 11827644
    Abstract: The present invention relates to a pyrazine derivative, an application thereof in inhibiting SHP2, and a compound of formula (I) or pharmaceutically acceptable salts, esters, isomers, solvates, prodrugs or isotope labels thereof. The structure of the compound of formula (I) is as follows. The novel pyrazine derivative provided by the present invention has excellent inhibition of SHP2 activity and can be used to prevent and/or treat non-receptor protein tyrosine phosphatase-mediated or dependent diseases or disorders.
    Type: Grant
    Filed: January 25, 2023
    Date of Patent: November 28, 2023
    Assignee: SUZHOU GENHOUSE PHARMACEUTICAL CO., LTD
    Inventors: Haifeng Sun, Kuifeng Wang, Tao Zhang, Mengnan Ma, Jinchang Lu
  • PYRAZINE DERIVATIVE AND APPLICATION THEREOF IN INHIBITING SHP2
    Publication number: 20230227464
    Abstract: The present invention relates to a pyrazine derivative, an application thereof in inhibiting SHP2, and a compound of formula (I) or pharmaceutically acceptable salts, esters, isomers, solvates, prodrugs or isotope labels thereof. The structure of the compound of formula (I) is as follows. The novel pyrazine derivative provided by the present invention has excellent inhibition of SHP2 activity and can be used to prevent and/or treat non-receptor protein tyrosine phosphatase-mediated or dependent diseases or disorders.
    Type: Application
    Filed: January 25, 2023
    Publication date: July 20, 2023
    Inventors: Haifeng SUN, Kuifeng WANG, Tao ZHANG, Mengnan MA, Jinchang LU
  • PYRAZINE DERIVATIVE AND APPLICATION THEREOF IN INHIBITING SHP2
    Publication number: 20220127276
    Abstract: The present invention relates to a pyrazine derivative, an application thereof in inhibiting SHP2, and a compound of formula (I) or pharmaceutically acceptable salts, esters, isomers, solvates, prodrugs or isotope labels thereof. The structure of the compound of formula (I) is as follows. The novel pyrazine derivative provided by the present invention has excellent inhibition of SHP2 activity and can be used to prevent and/or treat non-receptor protein tyrosine phosphatase-mediated or dependent diseases or disorders.
    Type: Application
    Filed: March 2, 2020
    Publication date: April 28, 2022
    Inventors: Haifeng SUN, Kuifeng WANG, Tao ZHANG, Mengnan MA, Jinchang LU