Patents by Inventor Kuiwon Choi

Kuiwon Choi has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 7510866
    Abstract: A hybrid bioreactor for cell culture is disclosed. To simultaneously apply compressive strain for cell differentiation and shear strain for cell proliferation to cells, the hybrid bioreactor includes a plurality of reactor tube assemblies (100), a compressive strain motor (5), a shear strain motor (25), a lower anchor mount (20) having a plurality of toothed anchors (70) to respectively anchor the lower ends of the reactor tube assemblies (100) to the lower anchor mount (20), a ball screw (90) operated in conjunction with the compressive strain motor (5), an upper anchor mount (60) which engages with the ball screw (90) to vertically move upward and downward and having a plurality of compressive strain anchors (80) to anchor the upper ends of the reactor tube assemblies (100) to the upper anchor mount (60), a power transmission unit to transmit the rotating force of the shear strain motor (25) to the toothed anchors (70).
    Type: Grant
    Filed: October 29, 2003
    Date of Patent: March 31, 2009
    Assignee: Korea Institute of Science and Technology
    Inventors: Kuiwon Choi, Tae Soo Bae, Jung Kyu Kim, Chang Yang Lee
  • Publication number: 20070148770
    Abstract: The present invention relates to macroporous chitosan beads having 5-200 ?m in size of relatively large and uniform pores that are distributed from surface to core region. The macroporous chitosan beads of the present invention make cell culturing efficient. Cells can attach to them efficiently due to their large surface area.
    Type: Application
    Filed: November 30, 2006
    Publication date: June 28, 2007
    Applicant: Korea Institute of Science and Technology
    Inventors: Seo Young JEONG, Eunhee BAE, Ick Chan KWON, Kuiwon CHOI
  • Publication number: 20060068492
    Abstract: A hybrid bioreactor for cell culture is disclosed. To simultaneously apply compressive strain for cell differentiation and shear strain for cell proliferation to cells, the hybrid bioreactor includes a plurality of reactor tube assemblies (100), a compressive strain motor (5), a shear strain motor (25), a lower anchor mount (20) having a plurality of toothed anchors (70) to respectively anchor the lower ends of the reactor tube assemblies (100) to the lower anchor mount (20), a ball screw (90) operated in conjunction with the compressive strain motor (5), an upper anchor mount (60) which engages with the ball screw (90) to vertically move upward and downward and having a plurality of compressive strain anchors (80) to anchor the upper ends of the reactor tube assemblies (100) to the upper anchor mount (60), a power transmission unit to transmit the rotating force of the shear strain motor (25) to the toothed anchors (70).
    Type: Application
    Filed: October 29, 2003
    Publication date: March 30, 2006
    Inventors: Kuiwon Choi, Jung Kim, Tae Bae, Chang Lee
  • Publication number: 20030119157
    Abstract: The present invention relates to macroporous chitosan beads having 5-200 &mgr;m in size of relatively large and uniform pores that are distributed from surface to core region, and a preparation method thereof compring the following steps; by dropping chitosan solution, aqueous chitosan solution or their mixture into the low-temperature of organic solvent or liquid nitrogen; and by regulating pore size by phase separation method via temperature difference.
    Type: Application
    Filed: June 17, 2002
    Publication date: June 26, 2003
    Inventors: Seo Young Jeong, Eunhee Bae, Ick Chan Kwon, Kuiwon Choi
  • Patent number: 6451348
    Abstract: A method of manufacturing a porous matrix-type drug delivery system is provided. It comprises the steps of: dispersing, stirring, and emulsifying an aqueous solution of a drug in an organic solvent having a polymer compound and a surface active agent solved therein; thereafter forming it into a desirable matrix shape; lyophilizing or drying it at a low temperature or room temperature until the matrix surface is hardened; and drying it again in order to remove the water and the organic solvent.
    Type: Grant
    Filed: January 3, 2000
    Date of Patent: September 17, 2002
    Assignee: Korea Institute of Science and Technology
    Inventors: Seo Young Jeong, Kuiwon Choi, Ick-Chan Kwon, Yong-Hee Kim, Jae Bong Choi, Kyu Back Lee