Patents by Inventor Kuldeepsinh Rana

Kuldeepsinh Rana has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METHOD TO FUNCTIONALIZE CELLS IN HUMAN BLOOD, OTHER FLUIDS AND TISSUES USING NANOPARTICLES
    Publication number: 20200009225
    Abstract: Compositions and methods for inhibiting metastatic cancer cells. The compositions comprise nanoparticles which have incorporated therein leukocyte adhesion molecules and therapeutic molecules exposed on their surface. The nanoparticles may be provided attached to leukocytes. Introduction of these compositions in to the circulation of individuals results in inhibition and reduction of metastatic cancer cells.
    Type: Application
    Filed: August 23, 2019
    Publication date: January 9, 2020
    Inventors: Michael R. King, Michael J. Mitchell, Kuldeepsinh Rana, Elizabeth C. Wayne, Chris B. Schaffer, Siddarth Chandrasekaran
  • Method to functionalize cells in human blood, other fluids and tissues using nanoparticles
    Patent number: 10391146
    Abstract: Compositions and methods for inhibiting metastatic cancer cells. The compositions comprise nanoparticles which have incorporated therein leukocyte adhesion molecules and therapeutic molecules exposed on their surface. The nanoparticles may be provided attached to leukocytes. Introduction of these compositions in to the circulation of individuals results in inhibition and reduction of metastatic cancer cells.
    Type: Grant
    Filed: August 4, 2014
    Date of Patent: August 27, 2019
    Assignee: Cornell University
    Inventors: Michael R. King, Michael J. Mitchell, Kuldeepsinh Rana, Elizabeth C. Wayne, Chris B. Schaffer, Siddarth Chandrasekaran
  • METHOD TO FUNCTIONALIZE CELLS IN HUMAN BLOOD, OTHER FLUIDS AND TISSUES USING NANOPARTICLES
    Publication number: 20160184395
    Abstract: Compositions and methods for inhibiting metastatic cancer cells. The compositions comprise nanoparticles which have incorporated therein leukocyte adhesion molecules and therapeutic molecules exposed on their surface. The nanoparticles may be provided attached to leukocytes. Introduction of these compositions in to the circulation of individuals results in inhibition and reduction of metastatic cancer cells.
    Type: Application
    Filed: August 4, 2014
    Publication date: June 30, 2016
    Inventors: Michael R. King, Michael J. Mitchell, Kuldeepsinh Rana, Elizabeth C. Wayne, Chris B. Schaffer, Siddarth Chandrasekaran
  • Continuous flow chamber device for separation, concentration, and/or purification of cells
    Publication number: 20090022768
    Abstract: The present invention relates to methods and apparatuses for neutralizing cancer cells. In particular, the invention relates to separating of cancer cell type from a mixture of different cell types based on the differential rolling property of cancer cell on a substrate coated with a first molecules that exhibits adhesive property with the particular cell type and neutralizing the cancer cell by a second molecule that is also coated on the substrate. This technology is adaptable for use in vivo, in vitro, or ex vivo tumor neutralization.
    Type: Application
    Filed: January 16, 2008
    Publication date: January 22, 2009
    Inventors: Michael R. King, Jane Liesveld, Kuldeepsinh Rana
  • Continuous flow chamber device for separation, concentration, and/or purfication of cells
    Publication number: 20070178084
    Abstract: The present invention relates to methods and apparatuses for cell separation. In particular, the invention relates to separation of a particular cell type from a mixture of different cell types based on the differential rolling property of the particular cell type on a substrate coated with molecules that exhibits adhesive property with the particular cell type. This technology is adaptable for use in implantable shunts and devices for cell trafficking or tumor neutralization.
    Type: Application
    Filed: December 4, 2006
    Publication date: August 2, 2007
    Inventors: Michael King, Nichola Charles, Jane Liesveld, John Gentile, Kuldeepsinh Rana, Nathan Clark, Nipa Mody