Abstract: An ultrasound therapy transducer head comprises an ultrasound source emitting ultrasonic radiation, the ultrasound source comprising a plurality of transducer elements, integrated driving electronics coupled to the transducer elements, the electronics generating at least one output ultrasound waveform and driving at least some of the transducer elements independently based on the at least one output ultrasound waveform and temperature control structure providing cooling for the electronics.

Abstract: An ultrasound therapy transducer head comprises an ultrasound source emitting ultrasonic radiation, the ultrasound source comprising a plurality of transducer elements, integrated driving electronics coupled to the transducer elements, the electronics generating at least one output ultrasound waveform and driving at least some of the transducer elements independently based on the at least one output ultrasound waveform and temperature control structure providing cooling for the electronics.

Abstract: An ultrasound therapy transducer head comprises an ultrasound source emitting ultrasonic radiation, the ultrasound source comprising a plurality of transducer elements, integrated driving electronics coupled to the transducer elements, the electronics generating at least one output ultrasound waveform and driving at least some of the transducer elements independently based on the at least one output ultrasound waveform and temperature control structure providing cooling for the electronics.

Abstract: A method of determining a property of a desired region in an object includes transmitting first and second energy beams from first and second sources into the object such that the beams intersect at the desired region to induce vibration of the desired region, transmitting energy from a third source into the desired region, receiving signals from the desired region due to the energy from the third source, and analyzing at least one of amplitude, phase and frequency of the vibration of the desired region indicated by the received signals to determine the property of the desired region.

Abstract: A method of opening a blood-organ barrier of a subject includes providing an exogenous agent configured to facilitate opening of the blood-organ barrier, administering the exogenous agent to a desired region of the subject, and applying energy to the desired region of the subject while the exogenous agent is present in the desired region, the energy being in a blood-organ-barrier-opening amount sufficient to induce opening of the blood-organ barrier of the subject with the exogenous agent present and below a damage amount sufficient to induce thermal damage to tissue in the absence of the exogenous agent.

Abstract: A method of opening a blood-organ barrier of a subject includes providing an exogenous agent configured to facilitate opening of the blood-organ barrier, administering the exogenous agent to a desired region of the subject, and applying energy to the desired region of the subject while the exogenous agent is present in the desired region, the energy being in a blood-organ-barrier-opening amount sufficient to induce opening of the blood-organ barrier of the subject with the exogenous agent present and below a damage amount sufficient to induce thermal damage to tissue in the absence of the exogenous agent.

Abstract: The present invention employs ultrasonic energy delivered to myocardial tissue at frequencies sufficient to destroy the myocardial tissue implicated in the arrhythmic. More specifically, the present invention comprises an ultrasonic transducer mounted on a distal end of a catheter and at least one electrode associated with the distal end region of the catheter. The ultrasonic transducer may be a single crystal transducer or a phased array crystal transducer.