Patents by Inventor Kumar Kamlesh SINGH

Kumar Kamlesh SINGH has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • PROCESS FOR PREPARATION OF MIDODRINE AND INTERMEDIATES THEREOF
    Publication number: 20220144754
    Abstract: The invention relates to process for the preparation of midodrine or pharmaceutically acceptable salts thereof. The invention also relates to process for the preparation of intermediates of midodrine.
    Type: Application
    Filed: November 10, 2021
    Publication date: May 12, 2022
    Inventors: Kumar Kamlesh Singh, Sanjay Jagdish Desai, Tadikonda Pratap V., Mahesh Laljibhai Rupapara
  • PROCESS FOR PREPARATION OF ISOXAZOLINE SUBSTITUTED BENZAMIDE COMPOUND
    Publication number: 20220064130
    Abstract: The invention relates to process for the preparation of isoxazoline-substituted benzamide compound and intermediates thereof. The invention also relates to process for the preparation of Fluralaner and intermediates thereof.
    Type: Application
    Filed: September 2, 2021
    Publication date: March 3, 2022
    Inventors: Kumar Kamlesh SINGH, Sanjay Jagdish DESAI, Kuldeep Natwarlal JAIN, Jitesh Amratlal DESAI, Sarvil Dhirajbhai PATEL
  • Process for preparation of grapiprant
    Patent number: 11254675
    Abstract: The invention relates to process for the preparation of grapiprant and its intermediates thereof. The invention also relates to grapiprant having a purity 98% or more and compounds of Formula (A), (B), (C) and (D) in an amount of 0.5 or less, relative to grapiprant, by area percentage of HPLC. The invention also relates to an amorphous form of grapiprant and process for preparation thereof.
    Type: Grant
    Filed: August 12, 2020
    Date of Patent: February 22, 2022
    Assignee: CADILA HEALTHCARE LIMITED
    Inventors: Kumar Kamlesh Singh, Jitendra Maganbhai Gajera, Sumer Singh Chundavat, Dipak Ambalal Patel
  • COMPOSITION COMPRISING HIGH PURITY PYRROLE DERIVATIVE AND METHOD FOR PREPARATION THEREOF
    Publication number: 20220023262
    Abstract: The present invention relates to a composition comprising high purity pyrrole derivative and method for preparation thereof. The present invention particularly relates to compositions comprising Saroglitazar magnesium having purity of 99.0% or more, and one or more of an aldehyde compound of Formula (II), diketo oxirane compound of Formula (III), hydroxy methyl compound of Formula (IV) or dimer compound of Formula (V), relative to saroglitazar magnesium, each present in an amount of about 0.15% or less, respectively, by weight, when measured by area percentage of HPLC.
    Type: Application
    Filed: July 23, 2021
    Publication date: January 27, 2022
    Inventors: Kumar Kamlesh SINGH, Sanjay Jagdish DESAI, Piyush Rajendra SHARMA, Daya Ram PAL, Sanjeev Kumar TRIPATHI, Mayur Ramnikbhai PATEL
  • PROCESS FOR PREPARATION OF GRAPIPRANT
    Publication number: 20210347776
    Abstract: The invention relates to process for the preparation of grapiprant and its intermediates thereof. The invention also relates to grapiprant having a purity 98% or more and compounds of Formula (A), (B), (C) and (D) in an amount of 0.5 or less, relative to grapiprant, by area percentage of HPLC. The invention also relates to an amorphous form of grapiprant and process for preparation thereof.
    Type: Application
    Filed: July 23, 2021
    Publication date: November 11, 2021
    Applicant: CADILA HEALTHCARE LIMITED
    Inventors: Kumar Kamlesh SINGH, Jitendra Maganbhai GAJERA, Sumer Singh CHUNDAVAT, Dipak Ambalal PATEL
  • PROCESS FOR PREPARATION OF FOSNETUPITANT
    Publication number: 20210214306
    Abstract: The present invention relates to a process for the preparation of fosnetupitant. The invention further relates to an amorphous fosnetupitant chloride hydrochloride and process for the preparation thereof.
    Type: Application
    Filed: January 13, 2021
    Publication date: July 15, 2021
    Applicant: CADILA HEALTHCARE LIMITED
    Inventors: Kumar Kamlesh SINGH, Sanjay Jagdish DESAI, Jagdish Maganbhai PATEL, Chirag Jayantilal VYAS, Dhaval Jashwantlal SOLANKI, Sudhir Ganpatbhai DHANANI
  • PROCESS FOR PREPARATION OF GRAPIPRANT
    Publication number: 20210079000
    Abstract: The invention relates to process for the preparation of grapiprant and its intermediates thereof. The invention also relates to grapiprant having a purity 98% or more and compounds of Formula (A), (B), (C) and (D) in an amount of 0.5 or less, relative to grapiprant, by area percentage of HPLC. The invention also relates to an amorphous form of grapiprant and process for preparation thereof.
    Type: Application
    Filed: August 12, 2020
    Publication date: March 18, 2021
    Applicant: CADILA HEALTHCARE LIMITED
    Inventors: Kumar Kamlesh SINGH, Jitendra Maganbhai GAJERA, Sumer Singh CHUNDAVAT, Dipak Ambalal PATEL
  • Process for preparation of apalutamide
    Patent number: 10934269
    Abstract: The present invention relates to a process for the preparation of apalutamide. In particular, the present invention relates to a process for the preparation of apalutamide and its intermediates. The present invention also relates to pharmaceutical compositions comprising apalutamide.
    Type: Grant
    Filed: September 27, 2019
    Date of Patent: March 2, 2021
    Assignee: CADILA HEALTHCARE LIMITED
    Inventors: Kumar Kamlesh Singh, Nikhil Amar Singh, Ganpatdan Shimbhu Charan, Nimeshkumar Mukeshkumar Shah
  • AMORPHOUS ERTUGLIFLOZIN AND PROCESS FOR ITS PREPARATION
    Publication number: 20200376017
    Abstract: An amorphous form of ertugliflozin and process for its preparation is described. A solid form of ertugliflozin and process for preparation thereof is also described.
    Type: Application
    Filed: May 29, 2020
    Publication date: December 3, 2020
    Applicant: CADILA HEALTHCARE LIMITED
    Inventors: Sanjay Jagdish DESAI, Tadikonda PRATAP V., Mahesh Laljibhai RUPAPARA, Kumar Kamlesh SINGH, Hardik Bhikhubhai GHODASARA
  • Process for preparation of apalutamide
    Patent number: 10807965
    Abstract: The present invention relates to a process for the preparation of apalutamide. In particular, the present invention relates to a process for the preparation of apalutamide and its intermediates. The present invention also relates to pharmaceutical compositions comprising apalutamide.
    Type: Grant
    Filed: March 27, 2019
    Date of Patent: October 20, 2020
    Assignee: CADILA HEALTHCARE LIMITED
    Inventors: Kumar Kamlesh Singh, Nikhil Amar Singh, Ganpat Dan Shimbhu Charan, Nimeshkumar Mukeshkumar Shah
  • A PROCESS FOR PREPARATION OF TRIAMINOPYRIMIDINE COMPOUND AND INTERMEDIATES THEREOF
    Publication number: 20200207738
    Abstract: The present invention relates to triaminopyrimidine compound 1, or pharmaceutically acceptable salts thereof, or hydrates, or solvates, or polymorphs, or optically active forms thereof, in solid state forms. The invention also relates to a process for preparation of triaminopyrimidine compound and intermediates thereof. The present invention also relates to a pharmaceutical composition comprising pure triaminopyrimidine compound, useful for preventing or treating malaria.
    Type: Application
    Filed: September 4, 2018
    Publication date: July 2, 2020
    Inventors: Kumar Kamlesh SINGH, Nikhil Amar SINGH, Ganapatdan Shimbhu CHARAN, Nimeshkumar Mukeshkumar SHAH, Sunil Dnyaneshwar NARODE, Dipakkumar Dhanjibhai VACHHANI, Amol Kashinath PATIL, Sandip Pundlik KHAIRNAR
  • PROCESS FOR PREPARATION OF APALUTAMIDE
    Publication number: 20200071287
    Abstract: The present invention relates to a process for the preparation of apalutamide. In particular, the present invention relates to a process for the preparation of apalutamide and its intermediates. The present invention also relates to pharmaceutical compositions comprising apalutamide.
    Type: Application
    Filed: March 27, 2019
    Publication date: March 5, 2020
    Applicant: CADILA HEALTHCARE LIMITED
    Inventors: Kumar Kamlesh SINGH, Nikhil Amar SINGH, Ganpat Dan Shimbhu CHARAN, Nimeshkumar Mukeshkumar SHAH
  • PROCESS FOR PREPARATION OF APALUTAMIDE
    Publication number: 20200024250
    Abstract: The present invention relates to a process for the preparation of apalutamide. In particular, the present invention relates to a process for the preparation of apalutamide and its intermediates. The present invention also relates to pharmaceutical compositions comprising apalutamide.
    Type: Application
    Filed: September 27, 2019
    Publication date: January 23, 2020
    Applicant: CADILA HEALTHCARE LIMITED
    Inventors: Kumar Kamlesh SINGH, Nikhil Amar SINGH, Ganpat Dan Shimbhu CHARAN, Nimeshkumar Mukeshkumar SHAH
  • Amorphous vortioxetine and salts thereof
    Patent number: 10414741
    Abstract: The present invention relates to an amorphous vortioxetine and salts thereof. In particular, the invention relates to a process for the preparation of an amorphous vortioxetine hydrobromide. Further, the invention also relates to a process for preparation of amorphous vortioxetine free base. The invention also relates to pharmaceutical compositions comprising an amorphous vortioxetine or hydrobromide salt thereof for oral administration for treatment of major depressive disorder (MDD) and generalized anxiety disorder (GAD).
    Type: Grant
    Filed: September 30, 2014
    Date of Patent: September 17, 2019
    Assignee: CADILA HEALTHCARE LIMITED
    Inventors: Shri Prakash Dhar Dwivedi, Kumar Kamlesh Singh, Jitendra Maganbhai Gajera, Dinesh Kumar Raikwar, Brij Khera
  • Crystalline form of rifaximin and process for its preparation
    Patent number: 9988398
    Abstract: A novel crystalline form of rifaximin and process for its preparation are described. A pharmaceutical composition comprising crystalline rifaximin is also described.
    Type: Grant
    Filed: June 6, 2017
    Date of Patent: June 5, 2018
    Assignee: CADILA HEALTHCARE LIMITED
    Inventors: Kumar Kamlesh Singh, Nikhil Amar Singh, Prashant Rameshchandra Bhatt, Amol Kashinath Patil
  • Amorphous form of linagliptin and process for preparation thereof
    Patent number: 9879011
    Abstract: The present invention relates to an amorphous form of linagliptin and processes for the preparation thereof. The invention also relates to a pharmaceutical composition comprising a therapeutically effective amount of an amorphous form of linagliptin and use of the composition for treatment of diabetes especially type-I or type-II, prediabetes or reduction of glucose tolerance.
    Type: Grant
    Filed: March 12, 2013
    Date of Patent: January 30, 2018
    Assignee: Cadila Healthcare Limited
    Inventors: Shriprakash Dhar Dwivedi, Ashok Prasad, Kuldeep Natwarlal Jain, Kumar Kamlesh Singh, Jitendra Maganbhai Gajera
  • NOVEL CRYSTALLINE FORM OF RIFAXIMIN AND PROCESS FOR ITS PREPARATION
    Publication number: 20170349608
    Abstract: A novel crystalline form of rifaximin and process for its preparation are described. A pharmaceutical composition comprising crystalline rifaximin is also described.
    Type: Application
    Filed: June 6, 2017
    Publication date: December 7, 2017
    Applicant: CADILA HEALTHCARE LIMITED
    Inventors: Kumar Kamlesh SINGH, Nikhil Amar SINGH, Prashant Rameshchandra BHATT, Amol Kashinath PATIL
  • PROCESS FOR PREPARATION OF ANDROGEN RECEPTOR ANTAGONIST
    Publication number: 20170158643
    Abstract: The present invention provides an isopropanol solvate of enzalutamide. The present invention also provides a process for the preparation of androgen receptor antagonist. In particular, the present invention provides a process for the preparation of enzalutamide or its pharmaceutically acceptable salts, hydrates, solvates, polymorphs or intermediates thereof.
    Type: Application
    Filed: February 23, 2017
    Publication date: June 8, 2017
    Inventors: Shri Prakash Dhar Dwivedi, Kumar Kamlesh Singh, Ganpat Dan Shimbhu Charan
  • Process for preparation of androgen receptor antagonist
    Patent number: 9611225
    Abstract: The present invention provides an isopropanol solvate of enzalutamide. The present invention also provides a process for the preparation of androgen receptor antagonist. In particular, the present invention provides a process for the preparation of enzalutamide or its pharmaceutically acceptable salts, hydrates, solvates, polymorphs or intermediates thereof.
    Type: Grant
    Filed: January 27, 2015
    Date of Patent: April 4, 2017
    Assignee: Cadila Healthcare Limited
    Inventors: Shri Prakash Dhar Dwivedi, Kumar Kamlesh Singh, Ganpat Dan Shimbhu Charan
  • Process for the preparation of apixaban
    Patent number: 9603846
    Abstract: A crystalline Form N-1 of apixaban substantially free from one or more of: 1-(4-methoxyphenyl)-7-oxo-6-(4-(2-oxopiperidin-1-yl)phenyl)-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxylic acid; 7-oxo-6-(4-(2-oxopiperidin-1-yl)phenyl)-1-phenyl-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxamide; or methyl 1-(4-methoxyphenyl)-7-oxo-6-(4-(2-oxopiperidin-1-yl)phenyl)-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxylate, relative to apixaban by area percentage of HPLC and having a mean particle size equal to or greater than 100 ?m.
    Type: Grant
    Filed: November 24, 2015
    Date of Patent: March 28, 2017
    Assignee: Cadila Healthcare Limited
    Inventors: Brij Khera, Kumar Kamlesh Singh, Santosh Devidas Diwakar, Sunil Dnyaneshwar Narode, Hiteshkumar Natwarlal Suthar