Abstract: The present invention relates to stable injectable compositions comprising meloxicam or its pharmaceutically acceptable salts, solvates, or hydrates thereof, wherein the composition is provided in a sealed container, e.g., an ampoule, vial and pre-filled syringe. Further, the present invention relates to a stable injectable solution comprising meloxicam or its pharmaceutically acceptable salts, solvates, or hydrates thereof, suitable for subcutaneous, intravenous or intramuscular administration. The invention relates to methods for manufacturing stable injectable solutions of meloxicam. The present invention further relates to a method of treating pain by parenterally administering to a patient in need thereof a composition comprising a stable solution of meloxicam, wherein said solution provides rapid onset of action for pain relief compared to a reference composition.

Abstract: Modified-release pharmaceutical compositions of ruxolitinib or a pharmaceutically acceptable salt thereof are disclosed. Preferably, the invention relates to oral modified-release pharmaceutical compositions of ruxolitinib, which enable once-daily administration. Oral modified-release compositions of ruxolitinib, methods for their administration, processes for their preparation, and use of these compositions for treatment of diseases treatable by ruxolitinib are also described.

Abstract: The present invention relates to injectable pharmaceutical compositions comprising therapeutically effective amount of succinylcholine chloride, one or more pharmaceutically acceptable aqueous solvents, and one or more stabilizing agents selected from aliphatic polyols; lower alkyl alcohols; amino acids having at least one additional amino, carboxyl or hydroxyl group; amino alcohols; and aliphatic dicarboxylic acids having at least one hydroxyl or amino group, or ?-? unsaturation. The compositions are stable at room temperature for at least 30 days. Methods of manufacturing the injectable pharmaceutical compositions are also provided. The composition may be provided in a sealed container, e.g., an ampoule, vial and pre-filled syringe, and are suitable for subcutaneous, intravenous or intramuscular administration as an adjunct to general anesthesia, to facilitate tracheal intubation, and/or to provide skeletal muscle relaxation during surgery or mechanical ventilation.

Abstract: Example methods and systems are directed to a managed inventory. A database may store information regarding items owned by a user. The information regarding an item may include a quantity owned and one or more triggering events. Based on the occurrence of a triggering event, an order for the item may be placed without user intervention. Data to the database may be provided by one or more sensors. Triggering events may be defined in terms of sensor data. The triggering event may be defined by a user or through machine learning. The order may be placed using a predetermined modality or a dynamically-determined modality based on one or more criteria, such as price, shipping speed, and the urgency of the order.

Abstract: A method including receiving a waveform, identifying the presence of a pulse in the waveform, and subtracting a reflection template from the received waveform when a pulse is present in the waveform to obtain a corrected waveform, is presented. The method may further include reading the corrected waveform using a digital processing protocol and adjusting a drilling parameter according to the reading. A device configured to perform a method as above is also provided. A method as above, further including modifying a drilling parameter in a wellbore based on the reading of a pulse sequence including the waveform is also provided.

Abstract: A system for channel sounding and initializing an equalizer using a frequency hopping sounder signal. The system identifies a frequency range for sounding a channel between a first device at a first location within a wellbore and a second device at a second location within the wellbore. Center frequencies, bandwidths, and timeframes are assigned to each of a plurality of sounding sequences, such that an entirety of the frequency range is assigned to the plurality of sounding sequences, and wherein when played in order according to the timeframe assigned to each sounding sequence in the plurality of sounding sequences, a sounding signal having a non-contiguous frequency is produced. By comparing an attenuated sounding signal based on the sounding signal to the sounding signal, the system estimates a transfer function of the channel. The system also initializes the equalizer based on the comparison.

Abstract: A method including receiving a waveform, identifying the presence of a pulse in the waveform, and subtracting a reflection template from the received waveform when a pulse is present in the waveform to obtain a corrected waveform, is presented. The method may further include reading the corrected waveform using a digital processing protocol and adjusting a drilling parameter according to the reading. A device configured to perform a method as above is also provided. A method as above, further including modifying a drilling parameter in a wellbore based on the reading of a pulse sequence including the waveform is also provided.

Abstract: A method and apparatus for testing an electronic device with multiple cores is provided. The method begins when at least one scan is input for scan configuring. A signal having a predetermined number of bits is then input to a decoder. The decoder then outputs at least one assigned test channel based on the output of the decoder. A test control block then switches at least one selected scan in channel to a test control block. A hard macro scan out of channels is then input to a channel maximization device which allocates or re-allocates the channels for testing. Testing proceeds once the channels are allocated. An apparatus includes a programmable scan configuration block for adjusting the number of scan out channels to maximize testing resources and a predetermined bit register in communication with the programmable scan configuration block.

Abstract: A system for channel sounding and initializing an equalizer using a frequency hopping sounder signal. The system identifies a frequency range for sounding a channel between a first device at a first location within a wellbore and a second device at a second location within the wellbore. Center frequencies, bandwidths, and timeframes are assigned to each of a plurality of sounding sequences, such that an entirety of the frequency range is assigned to the plurality of sounding sequences, and wherein when played in order according to the timeframe assigned to each sounding sequence in the plurality of sounding sequences, a sounding signal having a non-contiguous frequency is produced. By comparing an attenuated sounding signal based on the sounding signal to the sounding signal, the system estimates a transfer function of the channel. The system also initializes the equalizer based on the comparison.

Abstract: Embodiments contained in the disclosure provide a method of testing an electronic chip. The method comprises: scanning a test program into multiple clock registers; pulsing a clock to activate multiple asynchronous clock domain registers one at a time; staggering capture across and within the multiple asynchronous clock domains; shifting acquired data out of the multiple scan chains simultaneously; and then comparing the data scanned out with the test program data.

Abstract: A method for determining characteristics of a multi-material object is provided. The method includes producing a rotating electric field by providing an applied electrical signal set of individual electrical signal patterns to electrodes surrounding the multi-material object. The method also includes obtaining a measured electrical signal of electrical signals from the electrodes corresponding to each electrical signal pattern applied. An electrical network is determined based on the applied electrical signal set, the measured electrical signal set and an inverse of the applied electrical signal set. The method further includes determining the characteristics of the multi-material object by analyzing the electrical network.

Abstract: A method for determining characteristics of a multi-material object is provided. The method includes determining an electric element matrix representing the multi-material object. The electric element matrix is pre-multiplied by a first mathematical transformation matrix to obtain a first transformed electric element matrix. The first transformed electric element matrix is post-multiplied with a second mathematical transformation matrix to obtain a second transformed electric element matrix. The method further includes determining the characteristics of the multi-material object based on the second transformed electric element matrix.

Abstract: A method for determining characteristics of a multi-material object is provided. The method includes determining an electric element matrix representing the multi-material object. The electric element matrix is pre-multiplied by a first mathematical transformation matrix to obtain a first transformed electric element matrix. The first transformed electric element matrix is post-multiplied with a second mathematical transformation matrix to obtain a second transformed electric element matrix. The method further includes determining the characteristics of the multi-material object based on the second transformed electric element matrix.

Abstract: A method for determining characteristics of a multi-material object is provided. The method includes producing a rotating electric field by providing an applied electrical signal set of individual electrical signal patterns to electrodes surrounding the multi-material object. The method also includes obtaining a measured electrical signal of electrical signals from the electrodes corresponding to each electrical signal pattern applied. An electrical network is determined based on the applied electrical signal set, the measured electrical signal set and an inverse of the applied electrical signal set. The method further includes determining the characteristics of the multi-material object by analyzing the electrical network.

Abstract: A cosmetic skin care composition includes salicylhydroxamate or one or more other hydroxamate derivatives in an amount of about 0.001% to about 10.0% by weight, and nordihydroguaiaretic acid or one or more other antioxidants in an amount of about 0.00001% to about 10% by weight. The composition can be optionally encapsulated in a liposomal vehicle.

Abstract: An improved process for the preparation of sulfamate derivatives such as topiramate is provided comprising (a) reacting an alcohol with sulfuryl chloride in the presence of an amine base and in a first halogenated hydrocarbon solvent selected from the group consisting of aliphatic halogenated hydrocarbon solvents having 1 to 12 carbon atoms and at least three halogen atoms, aliphatic halogenated hydrocarbon solvents having 2 to 12 carbon atoms and less than three halogen atoms, aromatic halogenated hydrocarbon solvents having 6 to 18 carbon atoms and mixtures thereof to produce a chlorosulfate intermediate and (b) reacting the chlorosulfate intermediate with an amine of the formula R1NH2, wherein R1 is hydrogen or an alkyl from 1 to 4 carbon atoms, in a second halogenated hydrocarbon solvent selected from the group consisting of aliphatic halogenated hydrocarbon solvents having 1 to 12 carbon atoms and at least three halogen atoms, aliphatic halogenated hydrocarbon solvents having 2 to 12 carbon atoms and les

Abstract: A downlink telemetry system providing improved apparatus and methods for communicating instructions via pressure pulses from surface equipment to a downhole assembly. The apparatus comprises a surface transmitter for generating pressure pulses, a control system, and a downhole receiver for receiving and decoding pulses. In operation, a bypass valve is opened and closed to create a series of pressure pulses received and decoded by a downhole receiver. The method significantly reduces the time required for downlink communication without interrupting drilling and without interrupting uplink communications such that simultaneous, bi-directional communication is achievable if the uplink and downlink signals are sent at different frequencies. The telemetry scheme and algorithm provide an inventive method for filtering and decoding the downlink signals. The algorithm determines the time intervals between pulse peaks and decodes the intervals into an instruction.

Abstract: A downlink telemetry system providing improved apparatus and methods for communicating instructions via pressure pulses from surface equipment to a downhole assembly. The apparatus comprises a surface transmitter for generating pressure pulses, a control system, and a downhole receiver for receiving and decoding pulses.

Abstract: The invention provides a method of making tobacco rod in which method the tobacco filler material of the rod is subjected to radio frequency heating before feeding to a rod making machine. The elevated temperature increases the pliability of the tobacco filler, thus reducing its degradation in the rod making machine and enhancing the physical properties, e.g. ends stability, of the tobacco rods thus produced.