Patents by Inventor Kumar Sanjiv

Kumar Sanjiv has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METHOD FOR TREATING CANCER USING A COMBINATION OF CHK1 AND ATR INHIBITORS
    Publication number: 20220249489
    Abstract: The present invention relates to methods of treating cancer in a patient by administering a compound useful as an inhibitor of ATR protein kinase in combination with a compound useful as an inhibitor of Chk1 protein kinase. The aforementioned combination displays a surprising synergistic effect in treating cancer despite the targeted protein kinases being within the same biological pathway. Moreover, the present invention also relates to methods of treating cancer by administering a compound useful as an inhibitor of ATR protein kinase; administering a compound useful as an inhibitor of Chk1 protein kinase; as well as administering a DNA damaging agent to a patient. The compounds utilized in this invention are represented by formula I and formula II: wherein the variables are as defined herein.
    Type: Application
    Filed: September 20, 2021
    Publication date: August 11, 2022
    Inventors: Thomas HELLEDAY, Kumar SANJIV
  • Method for treating cancer using a combination of Chk1 and ATR inhibitors
    Patent number: 11179394
    Abstract: The present invention relates to methods of treating cancer in a patient by administering a compound useful as an inhibitor of ATR protein kinase in combination with a compound useful as an inhibitor of Chk1 protein kinase. The aforementioned combination displays a surprising synergistic effect in treating cancer despite the targeted protein kinases being within the same biological pathway. Moreover, the present invention also relates to methods of treating cancer by administering a compound useful as an inhibitor of ATR protein kinase; administering a compound useful as an inhibitor of Chk1 protein kinase; as well as administering a DNA damaging agent to a patient. The compounds utilized in this invention are represented by formula I and formula II: wherein the variables are as defined herein.
    Type: Grant
    Filed: June 17, 2015
    Date of Patent: November 23, 2021
    Assignee: VERTEX PHARMACEUTICALS INCORPORATED
    Inventors: Thomas Helleday, Kumar Sanjiv
  • METHOD FOR TREATING CANCER USING A COMBINATION OF CHK1 AND ATR INHIBITORS
    Publication number: 20150359797
    Abstract: The present invention relates to methods of treating cancer in a patient by administering a compound useful as an inhibitor of ATR protein kinase in combination with a compound useful as an inhibitor of Chk1 protein kinase. The aforementioned combination displays a surprising synergistic effect in treating cancer despite the targeted protein kinases being within the same biological pathway. Moreover, the present invention also relates to methods of treating cancer by administering a compound useful as an inhibitor of ATR protein kinase; administering a compound useful as an inhibitor of Chk1 protein kinase; as well as administering a DNA damaging agent to a patient. The compounds utilized in this invention are represented by formula I and formula II: wherein the variables are as defined herein.
    Type: Application
    Filed: June 17, 2015
    Publication date: December 17, 2015
    Inventors: Thomas Helleday, Kumar Sanjiv