Abstract: The present invention relates to stable pharmaceutical compositions for parenteral administration comprising aprepitant. The present invention further relates to a method for manufacturing the composition as well as to the use of these compositions. Also included are stable pharmaceutical compositions for parenteral administration comprising aprepitant and palonosetron. The pharmaceutical compositions are stable oil-in-water emulsions for parenteral administration and are particularly useful for the prevention and control of acute and delayed chemotherapy-induced nausea and vomiting (CINV), for the prevention of postoperative nausea and vomiting (PONV), and/or for the prevention of radiation induced nausea and vomiting (RINV).

Abstract: A cooling tower for evaporative cooling of water is contained within an ISO-compliant shipping container frame, permitting stacking of cooling towers for transport and for certain industrial applications. A volume of fill media is contained within the frame. Spaced apart troughs underlie the fill media, running substantially the length of the fill media and connecting to a basin. Baffles are connected to one upper edge of the troughs, while an air flow space is positioned over the other upper trough edge. A water distribution system, with variable flow nozzles positioned closely above the fill media, sprays water over the upper surface of the fill media, where it moves by gravity down into the troughs. Fans atop the fill media move air vertically upward through the fill media.

Abstract: The present invention relates to injectable pharmaceutical compositions comprising therapeutically effective amount of succinylcholine chloride, one or more pharmaceutically acceptable aqueous solvents, and one or more stabilizing agents selected from aliphatic polyols; lower alkyl alcohols; amino acids having at least one additional amino, carboxyl or hydroxyl group; amino alcohols; and aliphatic dicarboxylic acids having at least one hydroxyl or amino group, or ?-? unsaturation. The compositions are stable at room temperature for at least 30 days. Methods of manufacturing the injectable pharmaceutical compositions are also provided. The composition may be provided in a sealed container, e.g., an ampoule, vial and pre-filled syringe, and are suitable for subcutaneous, intravenous or intramuscular administration as an adjunct to general anesthesia, to facilitate tracheal intubation, and/or to provide skeletal muscle relaxation during surgery or mechanical ventilation.

Abstract: A cooling tower for evaporative cooling of water is contained within an ISO-compliant shipping container frame, permitting stacking of cooling towers for transport and for certain industrial applications. A volume of fill media is contained within the frame. Spaced apart troughs underlie the fill media, running substantially the length of the fill media and connecting to a basin. Baffles are connected to one upper edge of the troughs, while an air flow space is positioned over the other upper trough edge. A water distribution system, with variable flow nozzles positioned closely above the fill media, sprays water over the upper surface of the fill media, where it moves by gravity down into the troughs. Fans atop the fill media move air vertically upward through the fill media.

Abstract: The present invention relates to injectable pharmaceutical compositions comprising therapeutically effective amount of succinylcholine chloride, one or more pharmaceutically acceptable aqueous solvents, and one or more stabilizing agents selected from aliphatic polyols; lower alkyl alcohols; amino acids having at least one additional amino, carboxyl or hydroxyl group; amino alcohols; and aliphatic dicarboxylic acids having at least one hydroxyl or amino group, or ?-? unsaturation. The compositions are stable at room temperature for at least 30 days. Methods of manufacturing the injectable pharmaceutical compositions are also provided. The composition may be provided in a sealed container, e.g., an ampoule, vial and pre-filled syringe, and are suitable for subcutaneous, intravenous or intramuscular administration as an adjunct to general anesthesia, to facilitate tracheal intubation, and/or to provide skeletal muscle relaxation during surgery or mechanical ventilation.

Abstract: The present invention relates to injectable pharmaceutical compositions comprising therapeutically effective amount of succinylcholine chloride, one or more pharmaceutically acceptable aqueous solvents, and one or more stabilizing agents selected from aliphatic polyols; lower alkyl alcohols; amino acids having at least one additional amino, carboxyl or hydroxyl group; amino alcohols; and aliphatic dicarboxylic acids having at least one hydroxyl or amino group, or ?-? unsaturation. The compositions are stable at room temperature for at least 30 days. Methods of manufacturing the injectable pharmaceutical compositions are also provided. The composition may be provided in a sealed container, e.g., an ampoule, vial and pre-filled syringe, and are suitable for subcutaneous, intravenous or intramuscular administration as an adjunct to general anesthesia, to facilitate tracheal intubation, and/or to provide skeletal muscle relaxation during surgery or mechanical ventilation.

Abstract: The present invention relates to stable injectable compositions comprising meloxicam or its pharmaceutically acceptable salts, solvates, or hydrates thereof, wherein the composition is provided in a sealed container, e.g., an ampoule, vial and pre-filled syringe. Further, the present invention relates to a stable injectable solution comprising meloxicam or its pharmaceutically acceptable salts, solvates, or hydrates thereof, suitable for subcutaneous, intravenous or intramuscular administration. The invention relates to methods for manufacturing stable injectable solutions of meloxicam. The present invention further relates to a method of treating pain by parenterally administering to a patient in need thereof a composition comprising a stable solution of meloxicam, wherein said solution provides rapid onset of action for pain relief compared to a reference composition.

Abstract: The present invention relates to stable injectable compositions comprising meloxicam or its pharmaceutically acceptable salts, solvates, or hydrates thereof, wherein the composition is provided in a sealed container, e.g., an ampoule, vial and pre-filled syringe. Further, the present invention relates to a stable injectable solution comprising meloxicam or its pharmaceutically acceptable salts, solvates, or hydrates thereof, suitable for subcutaneous, intravenous or intramuscular administration. The invention relates to methods for manufacturing stable injectable solutions of meloxicam. The present invention further relates to a method of treating pain by parenterally administering to a patient in need thereof a composition comprising a stable solution of meloxicam, wherein said solution provides rapid onset of action for pain relief compared to a reference composition.

Abstract: Systems and method for delivery and positioning of a sheet-like surgical implant to a target site including a means of deploying and orienting the sheet-like implant within body.

Abstract: The present invention provides stable, ready-to-use pharmaceutical compositions, comprising dexmedetomidine or a pharmaceutically acceptable salt thereof, one or more pharmaceutically acceptable excipients, and a pharmaceutically acceptable liquid vehicle, where the composition is provided in a sealed container that comprises a cyclic olefin polymer. The present invention also provides ready-to-use pharmaceutical compositions comprising dexmedetomidine or a pharmaceutically acceptable salt thereof, a pharmaceutically acceptable liquid vehicle and an antioxidant and/or stabilizer, such as L-methionine. These solutions were found to be stable over the shelf life of the product. Other aspects of the invention relate to methods for making such compositions, as well as methods of using such compositions for perioperative care of a patient or for sedation.

Abstract: Methods and systems for processing a database query are disclosed. An example method includes receiving a SQL database query at a database query handling server, and parsing the SQL database query to identify a database and one or more tables and columns identified by the SQL database query. The method also includes determining a query plan based on the parsed database query. At a database engine, and based on the query plan and the identified database, tables and columns, the method further includes identifying a set of data nodes implicated by the identified database, tables and columns, determining a set of reduce operations and levels at which each of the set of map-reduce operations are to execute, and passing the query plan, the set of data nodes, and the map-reduce operations to a map-reduce query execution framework. The map-reduce query framework returns records as query results to the client system.

Abstract: A method for client side caching includes, with a client system, running a proxy caching application designed for execution on a proxy server, with a content presentation application running on the client system, accessing content from a server communicatively coupled to the client system, and with the proxy caching application, transparently caching the content into a cache system of the client system.

Abstract: Systems and methods for identifying a faulty node in a Hadoop cluster using an interface to the Hadoop cluster are described. A method may include receiving, at an interface to a Hadoop cluster, an input requesting diagnostic information for one or more nodes in the Hadoop cluster. The input may also specify the one or more nodes in the Hadoop cluster for which diagnostic information is requested. The method may further include initiating a diagnostic analysis of the one or more nodes, and displaying, at the interface, the diagnostic information for the one or more nodes. The diagnostic information may identify a node exhibiting a fault and be displayed while the diagnostic analysis is in progress.

Abstract: Systems and methods are described herein for administration of a Hadoop distributed computing network. The described embodiments include a graphical user interface (GUI) that facilitates administration and setup of a Hadoop system by removing the need for the administrator to enter complicated commands via a command line interface. The GUI also provides a visual indicator of the setup progress of the Hadoop system, among other benefits.

Abstract: Methods and systems for processing a database query are disclosed. An example method includes receiving a SQL database query at a database query handling server, and parsing the SQL database query to identify a database and one or more tables and columns identified by the SQL database query. The method also includes determining a query plan based on the parsed database query. At a database engine, and based on the query plan and the identified database, tables and columns, the method further includes identifying a set of data nodes implicated by the identified database, tables and columns, determining a set of reduce operations and levels at which each of the set of map-reduce operations are to execute, and passing the query plan, the set of data nodes, and the map-reduce operations to a map-reduce query execution framework. The map-reduce query framework returns records as query results to the client system.

Abstract: An herbal formulation for the modulation of immune system of HIV infected patients and a process of preparation thereof are provided. The process includes (i) preparing a hydromethanolic extract of at least one plant selected from Hippophae rhamnoides, Convolvulus pluricaulis, Withania somnifera, Ocimum sanctum, and Cynodon dactylon at 80-90° C., maintaining the pH of the solution between 6-7; (ii) separating the active compound chromatographically; and (iii) subjecting the active compounds to the step of molecular characterization.

Abstract: A method for client side caching includes, with a client system, running a proxy caching application designed for execution on a proxy server, with a content presentation application running on the client system, accessing content from a server communicatively coupled to the client system, and with said proxy caching application, transparently caching said content into a cache system of said client system.

Abstract: A graphical user interface system for a log analyzer having an input module, an output module, a merge module, and an export module. The input module selects one or more log files, and the output module displays the selected log files for analysis. The merging module performs time normalization for two or more log files from the selected log files, and merges the normalized log files. The export module can then export the merged log files.

Abstract: A graphical user interface system for BITS. The system includes a set of input modules, a set of output modules, and notification modules. The set of input modules allow selection of files for transfer to the BITS Server Virtual Directory and activate BITS functions. The BITS functions may include starting file transfer, cancelling file transfer, retrying file transfer, or removing the selected files. The set of output modules show dynamic status and real-time progress of the transfer automatically upon activation of the transfer of the selected files. The set of output modules also display an error message upon detecting an error in the transfer. Further, the notification modules provide a real-time notification on completion of the transfer.

Abstract: A method, system, and apparatus of minimizing configuration of changes in a fabric-based data protection solution. In one embodiment, a method includes configuring a switch such that a write request to a primary storage device is transferred through a virtual initiator in the switch to the primary storage device and to a secondary storage device, and configuring the switch such that a read request from the secondary initiator of a data in the primary storage device appears as though the read request is coming from a physical initiator rather than the secondary initiator (e.g., such that system protocol may be bypassed because the switch intercepts a response having the data from the primary storage device through a virtual target which uses the virtual initiator of the switch to communicate the data to the secondary initiator rather than the physical initiator).