Abstract: The present disclosure encompasses solid state forms of Ensifentrine, in embodiments crystalline polymorphs or salts of Ensifentrine, particularly Ensifentrine ethane-1.2-disulfonate, processes for preparation thereof, and pharmaceutical compositions thereof.

Abstract: Various embodiments include techniques for performing self-synchronizing remote memory operations in a multiprocessor computing system. During a remote memory operation in the multiprocessor computing system, a source processing unit transmits multiple segments of data to a destination processing. For each segment of data, the source processing unit transmits a remote memory operation to the destination processing unit that includes associated metadata that identifies the memory location of a corresponding synchronization object. The remote memory operation along with the metadata is transmitted as a single unit to the destination processing unit. The destination processing unit splits the operation into the remote memory operation and the memory synchronization operation. As a result, the source processing unit avoids the need to perform a separate memory synchronization operation, thereby reducing inter-processor communications and increasing performance of remote memory operations.

Abstract: Systems and methods for cleaning a processing chamber include supplying a pre-activated cleaning gas through a collar surrounding a showerhead stem into the processing chamber to clean the processing chamber. In other embodiments, a cleaning gas is supplied to the collar, and RF power is supplied to the showerhead or to a pedestal to generate plasma in the processing chamber to clean the processing chamber. In still other embodiments, an inert gas is supplied to the collar, a pre-activated cleaning gas is supplied to the showerhead stem, and RF power is supplied to the showerhead or to the pedestal to generate plasma in the processing chamber to clean the processing chamber.

Abstract: A center high-mounted stop lamp (CHMSL) system for a vehicle is provided. The CHMSL system includes a sensor, a primary CHMSL, a wireless secondary CHMSL, a vehicle wireless transceiver, and at least one processor coupled to the sensor, the primary CHMSL, and the vehicle wireless transceiver. The sensor is configured to generate sensor data, such as image data, proximity data, etc., associated with cargo loaded in a bed of the vehicle. The primary CHMSL includes a primary lamp. The wireless secondary CHMSL includes a secondary lamp, a battery, and control circuitry including a CHMSL wireless transceiver and a microcontroller. The processor is configured to facilitate, based on the sensor data, activation of the wireless secondary CHMSL. The processor is also configured to determine, based on the sensor data, whether the primary CHMSL is blocked or not blocked.

Abstract: Embodiments herein provide method of determining modulation and coding scheme (MCS) at a base station (BS). The method comprises obtaining, by the BS, downlink channel state information (DL-CSI) corresponding to a plurality of UEs. Also, the method comprises receiving feedback from the plurality of UEs, said feedback is at least one of explicit interference power and noise power feedback, post processing signal power-to-interference power plus noise power-based and determining MCS associated with a subset of UEs from the plurality of UEs using a predefined mapping between the MCS and a combination of DL-CSI and the feedback from the plurality of UEs. Further, the method comprises indicating the determined MCS to the subset of UEs from the plurality of UEs.

Abstract: The present invention relates to genetically modified Bacillus subtilis, compositions, and uses thereof in production of biomolecules and heterologous proteins and for delivery of biomolecules and heterologous proteins in animals and associated methods for improving animal health.

Abstract: Provided herein are systems and methods for sanitizing logged data packets in a distributed system prior to storing them in a remote or third-party data server. Interactions with an application are monitored and values in a data packet are extracted from the interaction. The values are classified based on a classification configuration and respective labels of the values. The values are then sanitized based on the classification to prevent exposure of secure or private data. The sanitized data packets are then logged into the remote data server. The logged data can be used to help resolve events occurring in the application. The classification configuration can be iteratively updated and the interactions repeated to capture data that was previously sanitized to aid in resolution of events. The logged data can also be used in research or analysis, such as for identifying potential improvements to the application.

Abstract: A retention flip flop includes a first latch, a second latch, and a retention latch. The first and second latches are powered by an interruptible primary supply voltage while the retention latch is powered by a secondary supply voltage that is not interrupted. The retention flip-flop receives a single retention control signal that controls whether the flip-flop is in a standard mode or a retention mode. In the retention mode, the flip-flop clock signal is paused.

Abstract: A computer-implemented method and system including generating a representation of an object associated with an equipment in an equipment management network, the object having an object type and being generated for a first user of the equipment management network; receiving, from the first user, an indication of whether a first other user is authorized to reshare the object via the equipment management network with a second other user of the equipment management network; receiving, from the first other user, an indication to reshare the object with the second other user; determining, based on a value of the indication of whether the first other user is authorized to reshare the object with the second other user, that the first other user is authorized to reshare the object with the second other user; and automatically resharing the object with the second other user without requesting approval from the first user.

Abstract: A system for generating virtual representations of architecture, engineering, and construction (AEC) smart constructs is disclosed. The system includes a controller that determines user intent based on an analysis of a user input and further determines project objective constraints based on an evaluation of project objectives. Knowledge units are computed based on a plurality of nodes and a plurality of interdependencies of a computational graph. The plurality of nodes corresponds to the user intent, and the plurality of interdependencies is established based on the project objectives. Based on the knowledge units, computational simulations for the user intent are performed. Further, virtual representations of the AEC smart constructs in a digital environment are generated based on the computational simulations. The computational simulations meet a defined criteria associated with the project objectives.

Abstract: This invention is directed to a catalytic hydrogenation process for the preparation of 1-(4-(benzyloxy)-3-(hydroxymethyl)phenyl)-2-(tert-butylamino)ethanol, which is an intermediate for the preparation of Salbutamol.

Abstract: A method includes capturing shipment milestone data of cost, insurance, and freight (CIF) shipments, recording the shipment milestone data within a distributed ledger, generating a training dataset using past shipment milestone data recorded within the distributed ledger, and generating a machine learning (ML) model configured with explainable artificial intelligence (XAI) based on the training dataset. The method also includes receiving information regarding a CIF shipment from a computing device, determining one or more relevant features from the information regarding the CIF shipment, the relevant features influencing prediction of a lead time for ownership transfer, and generating, using the ML model configured with XAI, a prediction of a lead time for ownership transfer with an explanation of the prediction for the CIF shipment based on the determined relevant features. The method may also include sending the prediction of the lead time for ownership transfer with the explanation to the computing device.

Abstract: In an example, a method includes executing, using one or more processors, a power-of-2 parametric activation (PACT2) function to quantize a set of data. The executing of the PACT2 function includes determining a distribution for the set of data; discarding a portion of the data corresponding to a tail of the distribution to form a remaining set of data; estimating a maximum value of the remaining set of data; determining a new maximum value of the remaining set of data using a moving average and at least one historical value of at least one prior remaining set of data; determining a clipping value by expanding the new maximum value to a nearest power of two value; and quantizing the set of data using the clipping value to form a quantized set of data.

Abstract: In one embodiment, a nozzle assembly includes a body with an internal surface forming an internal cavity within the body. The assembly also includes a gas inlet disposed within the body, a fluid inlet disposed within the body and a mixing chamber disposed within the internal cavity of the body, such that an annular gap is formed between the internal surface and an exterior surface of the mixing chamber, the mixing chamber may include: a mixing body region within the mixing chamber; one or more gas ports fluidly connecting the gas inlet to the mixing chamber, the gas ports tangentially aligned with an interior surface of the mixing chamber; a fluid port in fluid communication with the fluid inlet of the body and the mixing body region of the mixing chamber; and an outlet in fluid communication with the mixing body region configured to deliver a fluid mixture.

Abstract: An example methodology includes, by a computing device, receiving a recording of a virtual interview, the recording including an audio of the virtual interview and a video of the virtual interview, retrieving a profile image of a candidate, and determining an appearance of an interviewee in the video of the virtual interview. The method also includes, responsive to a determination that the appearance of the interviewee and profile image do not match, including, by the computing device, an indication that the candidate did not participate in the virtual interview in an assessment of authenticity of the candidate. The method further includes sending, by the computing device, a report of the assessment of the authenticity of the candidate to another computing device.

Abstract: SRAM cells are connected in columns by bit lines and connected in rows by first and second word lines coupled to first and second data storage sides of the SRAM cells. First the first word lines are actuated in parallel and then next the second word lines are actuated in parallel in first and second phases, respectively, of an in-memory compute operation. Bit line voltages in the first and second phases are processed to generate an in-memory compute operation decision. A low supply node reference voltage for the SRAM cells is selectively modulated between a ground voltage and a negative voltage. The first data storage side receives the negative voltage and the second data storage side receives the ground voltage during the second phase. Conversely, the second data storage side receives the negative voltage and the first data storage side receives the ground voltage during the first phase.

Abstract: In some examples, a system may determine route information for a route to be traversed by a vehicle from a start location to a destination location, the vehicle including a battery having a state of health. The system receives discharge data corresponding to traversal of the vehicle along the route, the discharge data indicative of a rate of discharge of the battery at a plurality of locations along the route. Based on the received discharge data, the system at least one of trains or updates a first machine learning model configured for predicting the state of health of the battery. The vehicle may determine an estimated battery state of health based at least on the first machine learning model, and may receive control information while traversing the route based on the estimated battery state of health to at least partially minimize battery degradation during traversal of the route.

Abstract: Retinal optical coherence tomography (OCT) with intraretinal layer segmentation is increasingly used not only in ophthalmology but also for neurological diseases such as multiple sclerosis (MS). Signal quality influences segmentation results, and high-quality OCT images are needed for accurate segmentation and quantification of subtle intraretinal layer changes. Among others, OCT image quality depends on the ability to focus, patient compliance and operator skills. Current criteria, for OCT quality define acceptable image quality, but depend on manual rating by experienced graders and are time consuming and subjective. In this paper, we propose and validate a standardized, grader-independent, real-time feedback system for automatic quality assessment of retinal OCT images. We defined image quality criteria for scan centering, signal quality and image completeness based on published quality criteria and typical artifacts identified by experienced graders when inspecting OCT images.

Abstract: Methods, systems and devices for detecting the presence of a pathogen, for example, a virus (e.g., SARS-COV-2), or its molecular components, in health care-related samples and/or environmental samples are disclosed. An example system for improving detection of a pathogen includes biosensor device comprising a detection chip and at least one probe that specifically recognizes a pathogen, where the detection chip comprises a graphene field-effect transistor (FET) chip and the probe, which comprises an aptamer, specifically binds to a DNA, RNA, or protein associated with the pathogen.

Abstract: Embodiments of the present disclosure are related, in general to communication, but exclusively related to methods and systems for improving coverage of a cellular network. The method comprising obtaining a transmission power capability of a user equipment (UE), and determining a time-frequency opportunities allocated to the UE and a modulation and coding scheme (MCS) associated with the UE. Thereafter, indicating an increase in the instantaneous transmit power level to the UE based on the transmission power capability of the UE, the time-frequency opportunities and the associated MCS. The method also comprises obtaining the number of Resource Elements (REs) available for PUSCH transmission. A Transport Block Size is obtained for the REs obtained and is transmitted by adding Cyclic Redundancy Check. The procedure also includes the usage of uplink symbols in special slots. The method also comprising the usage of Reference Symbols across the transmission opportunities based on the UE capability.