Patents by Inventor Kumiko Iida
Kumiko Iida has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
-
Publication number: 20240094210Abstract: A method for treating a specimen in soluble GPC3 immunoassay, the method including mixing a soluble GPC3-containing specimen with a reducing agent. A soluble GPC3 immunoassay method including the following (a) and (b): (a) mixing a soluble GPC3-containing specimen with a reducing agent; and (b) measuring the amount of soluble GPC3 in the mixture obtained in (a) using one or more kinds of antibodies against soluble GPC3. A soluble GPC3 immunoassay reagent including the following (a) and (b): (a) a reducing agent; and (b) one or more kinds of antibodies against soluble GPC3.Type: ApplicationFiled: January 17, 2022Publication date: March 21, 2024Applicant: FUJIREBIO INC.Inventors: Tomonori NISHII, Eriko SATO, Kumiko IIDA, Shintaro YAGI, Katsumi AOYAGI
-
Publication number: 20220326246Abstract: A lectin-binding substance measurement method is a method for measuring a lectin-binding substance in a sample, and includes: a capturing step of bringing a capture carrier including a water-insoluble carrier and a molecule immobilized on the water-insoluble carrier, the molecule being a molecule capable of capturing a lectin-binding substance, into contact with the sample to cause the capture carrier to capture the lectin-binding substance; a washing step of removing contaminants unbound to the capture carrier; a releasing step of releasing the lectin-binding substance from the capture carrier to obtain a prepared sample; and a measuring step of measuring the lectin-binding substance in the prepared sample by using a lectin.Type: ApplicationFiled: September 1, 2020Publication date: October 13, 2022Applicant: FUJIREBIO INC.Inventors: Kazunori OKADA, Kumiko IIDA, Shintaro YAGI, Katsumi AOYAGI
-
Publication number: 20220326245Abstract: A lectin-binding substance measurement method is a method for measuring a lectin-binding substance in a sample, and includes a measuring step of bringing a blocked labeled lectin including a water-soluble carrier made of a first water-soluble polymer and a labeling substance and a lectin immobilized on the water-soluble carrier into contact with the sample.Type: ApplicationFiled: September 1, 2020Publication date: October 13, 2022Applicant: FUJIREBIO INC.Inventors: Tomonori NISHII, Kazunori OKADA, Naoki ISHIKAWA, Kumiko IIDA, Shintaro YAGI, Katsumi AOYAGI
-
Patent number: 11454632Abstract: Disclosed is a highly sensitive assay method and assay kit for HBsAg, which do not require treatment with a strong acid or alkali in the sample pretreatment, and which is less susceptible to influences by the autoantibodies. The assay method for hepatitis B virus s antigen in a sample separated from a living body includes: a pretreatment step of mixing a sample with a pretreatment reagent containing a reducing agent, to reduce hepatitis B virus s antigen; and an immunoassay step of subjecting the pretreated sample to an immunoassay of hepatitis B virus s antigen using at least one antibody or antigen-binding fragment thereof capable of antigen-antibody reaction with a reduced peptide composed of the amino acids at positions 98 to 179 of hepatitis B virus s antigen.Type: GrantFiled: November 22, 2018Date of Patent: September 27, 2022Assignee: FUJIREBIO INC.Inventors: Chiharu Ohue, Kumiko Iida, Katsumi Aoyagi, Shintaro Yagi
-
Publication number: 20200371104Abstract: Disclosed is a highly sensitive assay method and assay kit for HBsAg, which do not require treatment with a strong acid or alkali in the sample pretreatment, and which is less susceptible to influences by the autoantibodies. The assay method for hepatitis B virus s antigen in a sample separated from a living body includes: a pretreatment step of mixing a sample with a pretreatment reagent containing a reducing agent, to reduce hepatitis B virus s antigen; and an immunoassay step of subjecting the pretreated sample to an immunoassay of hepatitis B virus s antigen using at least one antibody or antigen-binding fragment thereof capable of antigen-antibody reaction with a reduced peptide composed of the amino acids at positions 98 to 179 of hepatitis B virus s antigen.Type: ApplicationFiled: November 22, 2018Publication date: November 26, 2020Applicant: FUJIREBIO INC.Inventors: Chiharu OHUE, Kumiko IIDA, Katsumi AOYAGI, Shintaro YAGI
-
Patent number: 8546075Abstract: A method of treating samples containing hepatitis C virus (HCV) which method comprises treating HCV-containing samples with a treating agent containing (1) an acidifying agent, and (2) a protein-denaturing agent, or an amphoteric surfactant or a cationic surfactant having both a straight chain alkyl group of 10 or more carbon atoms and a tertiary amine or a quaternary ammonium salt in the same molecule, to effect the release of the HCV antigen and the inactivation of antibodies that bind to the HCV antigen, and the like.Type: GrantFiled: October 28, 2004Date of Patent: October 1, 2013Assignee: Advanced Life Science Institute, Inc.Inventors: Katsumi Aoyagi, Kumiko Iida, Naoko Matsubara
-
Publication number: 20110262892Abstract: A method for treating a virus-containing sample, characterized by treatment of a virus-containing sample with a treatment solution containing (1) an anionic surfactant and (2) an amphoteric surfactant, nonionic surfactant or protein denaturant; a virus assay method using said treating method; a method for treating a virus-containing sample, characterized by treatment of a virus-containing sample with a treatment solution containing (1) a chaotropic ion and (2) an acidifying agent; a virus assay method using said treating method; a virus assay method, characterized in that a virus antigen and a virus antibody are measured based on their binding to their probe in the presence of a surfactant with an alkyl group of 10 or more carbon atoms and a secondary, tertiary or quaternary amine, or a nonionic surfactant, or of both of them; and a monoclonal antibody and a hybridoma producing the same for carrying out said method.Type: ApplicationFiled: January 7, 2009Publication date: October 27, 2011Inventors: Katsumi Aoyagi, Chiharu Ohue, Kumiko Iida, Tatsuji Kimura, Shintaro Yagi
-
Patent number: 7776542Abstract: A method for treating a virus-containing sample, characterized by treatment of a virus-containing sample with a treatment solution containing (1) an anionic surfactant and (2) an amphoteric surfactant, nonionic surfactant or protein denaturant; a virus assay method using said treating method; a method for treating a virus-containing sample, characterized by treatment of a virus-containing sample with a treatment solution containing (1) a chaotropic ion and (2) an acidifying agent; a virus assay method using said treating method; a virus assay method, characterized in that a virus antigen and a virus antibody are measured based on their binding to their probe in the presence of a surfactant with an alkyl group of 10 or more carbon atoms and a secondary, tertiary or quaternary amine, or a nonionic surfactant, or of both of them; and a monoclonal antibody and a hybridoma producing the same for carrying out said method.Type: GrantFiled: August 4, 1998Date of Patent: August 17, 2010Assignee: Advanced Life Science InstituteInventors: Katsumi Aoyagi, Chiharu Ohue, Kumiko Iida, Tatsuji Kimura, Shintaro Yagi
-
Publication number: 20080044807Abstract: A method of treating samples containing hepatitis C virus (HCV) which method comprises treating HCV-containing samples with a treating agent containing (1) an acidifying agent, and (2) a protein-denaturing agent, or an amphoteric surfactant or a cationic surfactant having both a straight chain alkyl group of 10 or more carbon atoms and a tertiary amine or a quaternary ammonium salt in the same molecule, to effect the release of the HCV antigen and the inactivation of antibodies that bind to the HCV antigen, and the like.Type: ApplicationFiled: October 28, 2004Publication date: February 21, 2008Applicant: Advanced Life Science Institute, Inc.Inventors: Katsumi Aoyagi, Kumiko Iida, Naoko Matsubara
-
Patent number: 7316905Abstract: A method for measurement of the hepatitis C virus (HCV) characterized by measuring HCV core antigen and HCV core antibody by their binding with probes in the presence of an anionic surfactant or a non-ionic surfactant, or both.Type: GrantFiled: July 30, 1999Date of Patent: January 8, 2008Assignee: Advanced Life Science Institute, Inc.Inventors: Katsumi Aoyagi, Chiharu Ohue, Kumiko Iida, Shintaro Yagi
-
Publication number: 20070298435Abstract: [PROBLEMS] To provide a soluble highly sensitive probe complex with high functional capability ensuring usability in immunoassays of high sensitivity. [MEANS FOR SOLVING PROBLEMS] A highly sensitive probe complex can be produced by linking hydrophilic intermediums to a carrier and linking detection markers such as biotin, haptens or low-molecular-weight peptides and antibodies to the intermediums. By virtue of the linking of hydrophilic intermediums to a carrier, a multiplicity of hapten molecules can be linked and the probe complex as a whole becomes hydrophilic, so that there can be obtained a probe complex with high functional capability which would not induce nonspecific reactions.Type: ApplicationFiled: July 28, 2005Publication date: December 27, 2007Inventors: Katsumi Aoyagi, Kumiko Iida, Naoko Matsubara, Takehiko Ishida
-
Patent number: 6623921Abstract: A method for measurement of the hepatitis C virus (HCV) characterized by measuring HCV core antigen and HCV core antibody by their binding with probes in the presence of an anionic surfactant or a non-ionic surfactant, or both.Type: GrantFiled: April 26, 2002Date of Patent: September 23, 2003Assignee: Advanced Life Science Institute, Inc.Inventors: Katsumi Aoyagi, Chiharu Ohue, Kumiko Iida, Shintaro Yagi
-
Publication number: 20020173493Abstract: A method for measurement of the hepatitis C virus (HCV) characterized by measuring HCV core antigen and HCV core antibody by their binding with probes in the presence of an anionic surfactant or a non-ionic surfactant, or both.Type: ApplicationFiled: April 26, 2002Publication date: November 21, 2002Applicant: ADVANCED LIFE SCIENCE INSTITUTE, INC.Inventors: Katsumi Aoyagi, Chiharu Oheu, Kumiko Iida, Shintaro Yagi