Patents by Inventor Kumiko Iwai

Kumiko Iwai has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method of NMR imaging
    Patent number: 5811077
    Abstract: A gadolinium complex of 1,4,7,10-tetraazacyclododecane-1,4,7,10-.alpha.,.alpha.',.alpha.",.alpha." '-tetrakis(methylacetic acid) or its salt, which is useful as a nuclear magnetic resonance imaging agent.
    Type: Grant
    Filed: December 18, 1996
    Date of Patent: September 22, 1998
    Assignee: Nihon Medi-Physics Co., Ltd.
    Inventors: Shigemi Seri, Makoto Azuma, Kumiko Iwai
  • Low molecular weight polysaccharide complexes for radiation diagnosis
    Patent number: 5422095
    Abstract: There is disclosed an imaging agent for diagnosis comprising a compound composed of a polynuclear type compound of the formula I or II: ##STR1## wherein each X is a hydrogen atom or a bifunctional ligand, at least one of them are bifunctional ligand and m or n is an integer of 1 to 6, and at least one metal ion being coordinated with at least one bifunctional ligand moiety, said metal ion being selected from the group consisting of metal ions having the atomic number of 21-29, 31, 32, 37-39, 42-44, 49 and 56-83.
    Type: Grant
    Filed: April 4, 1994
    Date of Patent: June 6, 1995
    Assignee: Nihon Medi-Physics Co., Ltd.
    Inventors: Yuji Hashiguchi, Kumiko Iwai, Shigemi Seri, Susumu Kondo, Makoto Azuma
  • Low molecular weight polysaccharide complexes for X-ray imaging
    Patent number: 5352431
    Abstract: There is disclosed an imaging agent for diagnosis comprising a compound composed of a polynuclear type compound of the formula I or II: ##STR1## wherein each X is a hydrogen atom or a bifunctional ligand, at least one of them are bifunctional ligand and m or n is an integer or 1 to 6, and at least one metal ion being coordinated with at least one bifunctional ligand moiety, said metal ion being selected from the group consisting of metal ions having the atomic number of 21-29, 31, 32, 37-39, 42-44, 49 and 56-83.
    Type: Grant
    Filed: September 13, 1993
    Date of Patent: October 4, 1994
    Assignee: Nihon Medi-Physics Co., Ltd.
    Inventors: Yuji Hashiguchi, Kumiko Iwai, Shigemi Seri, Susumu Kondo, Makoto Azuma
  • Nuclear magnetic resonance imaging agent comprising a di-aldehyde complex
    Patent number: 5271929
    Abstract: There is disclosed a nuclear magnetic resonance imaging agent comprising a complex compound composed of (a) a dialdehyde-saccharide having a molecular weight of from 500 to 10,000, at least one of the constituent monosaccharides of which is oxidation-cleaved, (b) at least one complexing agent which is chemically coupled to an aldehyde group of the dialdehyde-saccharide and (c) a paramagnetic metal ion which is chemically coupled to the complexing agent.
    Type: Grant
    Filed: July 8, 1992
    Date of Patent: December 21, 1993
    Assignee: Nihon Medi-Physics Co., Ltd.
    Inventors: Yuji Hashiguchi, Kumiko Iwai, Shigemi Seri, Susumu Kondo, Makoto Azuma
  • Low molecular weight polysaccharide complexes for nuclear magnetic resonance imaging
    Patent number: 5271924
    Abstract: There is disclosed an imaging agent for diagnosis comprising a compound composed of a polynuclear type compound of the formula I or II: ##STR1## wherein each X is a hydrogen atom or a bifunctional ligand, at least one of them are bifunctional ligand and m or n is an integer of 1 to 6, and at least one metal ion being coordinated with at least one bifunctional ligand moiety, said metal ion being selected from the group consisting of metal ions having the atomic number of 21-29, 31, 32, 37-39, 42-44, 49 and 56-83.
    Type: Grant
    Filed: September 29, 1992
    Date of Patent: December 21, 1993
    Assignee: Nihon Medi-Physics Co., Ltd.
    Inventors: Yuji Hashiguchi, Kumiko Iwai, Shigemi Seri, Susumu Kondo, Makoto Azuma