Abstract: Described herein is the preparation and use of amino acid-modified lipids for delivery of a small interfering RNA (siRNA), mRNA, miRNA, shRNA, or oligonucleotide via formation of lipid nanoparticles (LNPs) comprising the siRNA, mRNA, miRNA, shRNA, or oligonucleotide and the amino acid-modified lipid. Use of the described lipid nanoparticles to silence overexpression of oncogenes is described.

Abstract: A modular robot vehicle comprising of a power module, a plurality of motor modules, a plurality of wheel or propeller drive modules, entertaining module, and an optional attachment module, where a combination of different modules can be selectively replaceable and configurable to fulfill a desired function in accordance with capabilities of an extension module and practical requirements. The extension module may be one of a plurality of interchangeable, heterogenous extension modules that are operably attachable to the vehicle body.

Abstract: A database access method and apparatus are disclosed, to ensure data security during interaction between a user and a database, and effectively reduce performance overheads. The method includes: receiving an encrypted data computation request sent by a database kernel, where the encrypted data computation request requests to perform computation on encrypted data of a user, and the database kernel runs in a non-secure execution environment; receiving encrypted data sent by the database kernel, where the encrypted data is all encrypted data in a user query request; performing decryption and computation on the encrypted data in response to the encrypted data computation request, to obtain a computation result; encrypting the computation result to obtain an encrypted computation result; and sending the encrypted computation result to the database kernel.

Abstract: The present disclosure provides an energy storage system control method, device, and energy storage system, which relate to the technical field of photovoltaic. The energy storage system control method according to the present disclosure includes: acquiring a PV voltage, a battery voltage and a grid-side voltage, determining a bus voltage reference value according to the PV voltage, the battery voltage and the grid-side voltage, and determining a phase shifting angle reference or a frequency reference according to the bus voltage reference value; acquiring a current on battery side, and determining a bridge arm phase shifting angle change amount or frequency change amount according to a low-frequency component of the current on battery side needing to be suppressed; determining a bridge arm phase shifting angle according to the phase shifting angle reference and the bridge arm phase shifting angle change amount.

Abstract: An REE and a TEE are deployed in the terminal device. The data processing method includes: storing, in the REE, an ecall task initiated by a CA through a first thread into a shared memory; obtaining, in the TEE, the ecall task from the shared memory; and executing, by a TA in the TEE, the ecall task through a second thread, and storing a task result into the shared memory. The shared memory is pre-applied in the REE for the CA and can be accessed by the REE and the TEE. The second thread is created in the TEE. The second thread and the first thread are bound to different processing units. The shared memory is pre-applied, to avoid data copy. Processing units bound to threads that execute the ecall task in the REE and the TEE are different, and the second thread is created in the TEE.

Abstract: Aspects disclosed herein relate to compositions comprising novel phosphoinositide 3-kinase (PI3K) inhibitors, and methods of making the novel PI3K inhibitors. Further, various aspects relate to one or more methods of treating a disease using the compositions disclosed herein, including targeted delivery of the novel PI3K inhibitors disclosed herein.

Abstract: Polypeptides and compositions having the polypeptides. Methods for treating cancer utilizing polypeptides and compositions having the polypeptides. The polypeptides can bind to human PD-L1 protein. The polypeptides can block the PD-1/PD-L1 interaction.

Abstract: The present application belongs to the field of lithium battery technology, particularly relating to a preparation method for lithium iron phosphate cathode material and lithium battery. The method comprises: adding lithium source, iron source, phosphorus source, first carbon source, dopant, and dispersant into a solvent according to a preset ratio for mixing and grinding treatment to obtain the first mixture; Drying the first mixture and performing the first sintering in an inert gas atmosphere to obtain the lithium iron phosphate precursor; Adding borohydride, deionized water, second carbon source, and dispersant to the lithium iron phosphate precursor for pretreatment to obtain the lithium iron phosphate precursor mixture; After mixing, grinding, and drying the lithium iron phosphate precursor mixture, performing a second sintering in an inert gas atmosphere to obtain a coated doped type lithium iron phosphate cathode material.

Abstract: The present application belongs to the field of lithium battery technology, particularly relating to a preparation method for ultra-high compacted lithium iron phosphate cathode material and lithium battery. The method comprises: obtaining an iron-containing precursor based on iron phosphate and dispersant; Mixing the iron-containing precursor, lithium source, phosphorus source, and first carbon source for first sintering to obtain the first precursor mixture and grinding to the first preset particle size to obtain the first precursor; Mixing the iron-containing precursor, lithium source, phosphorus source, and second carbon source for second sintering to obtain the second precursor mixture and grinding to the second preset particle size to obtain the second precursor; Mixing the first precursor, second precursor, and third carbon source and performing a third sintering to obtain the lithium iron phosphate cathode material, improving the coating integrity of the first carbon coating.

Abstract: A method for preparing (2S,3R)-p-methylsulfonylphenylserine is provided. In order to solve the existing problem of low conversion rate, provided is a method for preparing (2S,3R)-p-methylsulfonylphenylserine, including carrying out a reaction between p-methylsulfonylbenzaldehyde, L-threonine and pyridoxal phosphate in an oxygen-containing environment under the combined action of transaldolase and acetaldehyde oxidase to obtain a product (2S,3R)-p-methylsulfonylphenylserine. The method can effectively achieve the effect of improving the conversion rate of the reaction and has the advantage of high product yield.

Abstract: Disclosed are a magnetic attraction type fixed charging device and a magnetic attraction type fixed charging method. The device includes a connection status acquisition module for acquiring equipment interface and circuit connection information and uploading same to a database; a database module for choosing whether to charge or not based on the information in the database; a charging status acquisition module for acquiring equipment status information during charging and uploading same to a cloud; a charging mode selection module for selecting a charging mode based on the equipment status information in the cloud; and a data feedback module for sending the equipment status information and the charging mode to a bound mobile intelligent terminal. The present application solves the technical problem that the traditional string-type charging equipment is not capable of controlling the charging power, and the fault location cannot be known in time, which makes the detection process complicated.

Abstract: Hydrocarbon extraction processes utilizing a cleansing bed to cleanse at least a portion of a lean-solvent stream are disclosed. The cleansing bed can preferentially include abed of activated carbon, abed of alumina, and/or a bed of an ion-exchange resin. The extraction process can use a liquid/liquid extraction column or an extraction distillation column. The process can be particularly advantageous for removing C10-C20 contaminants, among others, from the lean-solvent stream.

Abstract: A self-moving snow removal device and a safe snow throwing method protecting a human or an object from damage by snow or miscellaneous matter. The snow removal device includes: a moving module, driving the snow removal device to move; a working module, including a working motor and a snow throwing mechanism, where the snow throwing mechanism is driven by the working motor to collect accumulated snow and miscellaneous matter on the ground and throw the accumulated snow and miscellaneous matter out of the snow throwing mechanism, and a maximum height of a thrown object in the air from the ground is referred to as a snow throwing height; and a control module, configured to control the working module or the moving module to enable the snow throwing height to be less than a predetermined snow throwing height threshold.

Abstract: Hydrocarbon extraction processes utilizing a cleansing bed to cleanse at least a portion of a lean-solvent stream are disclosed. The cleansing bed can preferentially include abed of activated carbon, abed of alumina, and/or a bed of an ion-exchange resin. The extraction process can use a liquid/liquid extraction column or an extraction distillation column. The process can be particularly advantageous for removing C10-C20 contaminants, among others, from the lean-solvent stream.

Abstract: A database access method and apparatus are disclosed, to ensure data security during interaction between a user and a database, and effectively reduce performance overheads. The method includes: receiving an encrypted data computation request sent by a database kernel, where the encrypted data computation request requests to perform computation on encrypted data of a user, and the database kernel runs in a non-secure execution environment; receiving encrypted data sent by the database kernel, where the encrypted data is all encrypted data in a user query request; performing decryption and computation on the encrypted data in response to the encrypted data computation request, to obtain a computation result; encrypting the computation result to obtain an encrypted computation result; and sending the encrypted computation result to the database kernel.

Abstract: The present disclosure provides a smart lock, including: a lock body and an unlocking structure; a Bluetooth communication module configured to receive a lock instruction or an unlock instruction based on Bluetooth communication; and one or more binding tags, each binding tag being associated with a Bluetooth address of the smart lock, wherein the unlocking structure is configured to lock or unlock the smart lock based on the lock instruction or the unlock instruction, or lock or unlock the smart lock based on an operation performed for the one or more binding tags. The present disclosure further provides a system and method for monitoring an object equipped with the smart lock.

Abstract: Described herein is the discovery of novel PSMA-specific peptides, which were identified through a novel combinatorial biopanning method. One of the novel PSMA-specific peptides discovered, GTIQPYPFSWGY (or GTI) (SEQ ID NO: 2), exhibits high binding affinity and selectivity to PSMA and PSMA-positive prostate cancer cells. It was found that GTI can mediate internalization of the apoptotic KLA peptide to PSMA-positive LNCaP cells and induce cell death. Moreover, a FAM-labeled GTI peptide shows a high and specific tumor uptake in nude mice bearing human prostate cancer xenografts. It was demonstrated that the GTI peptide can be employed as a PSMA-specific ligand for prostate cancer diagnosis and/or for targeted drug delivery to prostate cancer cells.