Abstract: In an aspect of the disclosure, a method, a computer-readable medium, and an apparatus are provided. The apparatus may be a UE. In certain configurations, the UE enters a first radio resource control (RRC) connection with a first base station of a first network. The UE receives, from the first base station, an indication that enables the UE to send a first request for deactivating or releasing resources used for communications with the first base station. In response to a determination to enter a second RRC connection with a second base station of a second network, the UE sends, to the first base station, the first request for deactivating or releasing the resources. The UE enters the second RRC connection with the second base station while maintaining the first RRC connection with the first base station.

Abstract: A drug ranking method, a drug ranking system and a comparison method for drug ranking method are provided. The processing unit executes ranking a plurality of drugs according to a protein target, comparing a plurality of drug ranking methods, and correcting a drug ranking method.

Abstract: Provided is a method for determining a drug combination targeting different sites of a protein or a protein complex, including: identifying a first binding site and a second binding site of the protein or the protein complex based on a three-dimensional structure thereof, wherein the first binding site and the second binding site are different sites in the three-dimensional structure of the protein or the protein complex; identifying a first drug interacting with the first binding site; identifying a second drug interacting with the second binding site; and combining the first drug and the second drug to provide at least one of a synergistic effect and an additive effect in suppressing an activity of the protein or the protein complex. Also provided is a method for treating a ATG4B-related disease or a 3C-like protease-related disease by the drug combination.

Abstract: The fuel economizer is series-connected between a fuel tank and a fuel vaporization device of an internal combustion engine, and includes a first piping element and an oil cup. A first end of the first piping element is connected to the fuel vaporization device, and a second end of the first piping element is connected to the fuel tank through the oil cup for filtering the fuel tank's fuel. A spirally threaded shaft is tightly housed inside the first piping element and the spirally threaded shaft's outer circumference is configured with spiral threads to speed, rotate, and disturb the fuel as the fuel flows through to disrupt the surface tension and density of the fuel.

Abstract: Provided is a method for treating a SARS-CoV2 3CLpro-related disease in a subject in need thereof by blocking dimerization of 3C-like main protease (3CLpro) of the SARS-CoV2, including administering to the subject a first agent which binds to a first binding site of a SARS-CoV2 3CLpro complex and a second agent which binds to a second binding site of the SARS-CoV2 3CLpro complex, wherein the first binding site and the second binding site are functionally different sites in the three-dimensional structure of the SARS-CoV2 3CLpro complex. Also provided is a pharmaceutical combination including the first agent and the second agent for suppressing SARS-CoV2, thereby alleviating COVID-19.

Abstract: The present invention relates to the area of ATG4-related disorders. More particularly, the present invention relates to a method of treating an ATG4B-related disorder comprising a step of administering a subject with an effective amount of tioconazole. The present invention relates also to a method of increasing a subject's responsiveness to a therapy for a cancer comprising inhibition of ATG4B activity in cells; said method comprises administering the subject with an effective amount of tioconazole. The present invention also relates to a method for enhancing or inducing a response in a cancer cell consisting of cytotoxicity, chemosensitivity or starvation-sensitivity; said method comprises administering a subject with an effective amount of tioconazole to inhibit ATG4B's activity.

Abstract: The present invention relates to the area of ATG4-related disorders. More particularly, the present invention relates to a method of treating an ATG4B-related disorder comprising a step of administering a subject with an effective amount of tioconazole. The present invention relates also to a method of increasing a subject's responsiveness to a therapy for a cancer comprising inhibition of ATG4B activity in cells; said method comprises administering the subject with an effective amount of tioconazole. The present invention also relates to a method for enhancing or inducing a response in a cancer cell consisting of cytotoxicity, chemosensitivity or starvation-sensitivity; said method comprises administering a subject with an effective amount of tioconazole to inhibit ATG4B's activity.

Abstract: A power-saving controlling method includes steps as follows. An electrical information is captured from an electrical equipment by an intelligent socket device. The electrical information is calculated and a rule table is generated. An automatic controlling signal is generated according to the rule table. The intelligent socket device is switched off or switched on according to the automatic controlling signal.

Abstract: An image reading apparatus includes a housing, a rod lens array, a light module and a sensor board. The housing accommodates the rod lens array, the light module and the sensor board. The sensor board includes a plurality of light sensor chips. The light module includes a light guide, a light source and guide terminals extending from the light source. The guide terminals are electrically connected to the sensor board with resilient contacts.

Abstract: An image reading apparatus includes a housing, a rod lens array, a light module and a sensor board. The housing accommodates the rod lens array, the light module and the sensor board. The sensor board includes a plurality of light sensor chips. The light module includes a light guide, a light source and guide terminals extending from the light source. The guide terminals are electrically connected to the sensor board with resilient contacts.

Abstract: A testing system selects one of testing paths based on a control unit and a test switching unit for randomly executing tests upon a plurality of products based on the testing requirements of each of examining units, so as to decrease the costs of equipment, interference between the tests on several products, the idle time of a testing devise and the testing period for tested products.