Abstract: Disclosed are a polyethylene glycol conjugate drug, and a preparation method therefor and the use thereof. Specifically, the present invention relates to a polyethylene glycol conjugate drug represented by formula A or a pharmaceutically acceptable salt thereof, a method for preparing the polyethylene glycol conjugate drug or the pharmaceutically acceptable salt thereof, an intermediate for preparing the polyethylene glycol conjugate drug or the pharmaceutically acceptable salt thereof, a pharmaceutical composition comprising the polyethylene glycol conjugate drug or the pharmaceutically acceptable salt thereof, and the use of the polyethylene glycol conjugate drug or the pharmaceutically acceptable salt thereof in the preparation of a drug.

Abstract: A bottom cylinder for a high-temperature and high-pressure environment simulator of a high-fidelity corer is provided. The bottom cylinder includes a cylinder barrel. The bottom of the cylinder barrel is provided with a cylinder base. The piston is provided inside the cylinder barrel and divides an inner cavity of the cylinder barrel into a rodless cavity and a rod cavity. The piston is provided with a piston rod. The outer wall of the cylinder barrel is provided with an oil inlet hole communicated with the rodless cavity, an oil outlet hole communicated with the rod cavity, and a reserved hole. The lower end surface of the piston is provided with a first buffer ring, and the upper surface of the cylinder base is provided with a second buffer ring mated with the first buffer ring. The bottom cylinder is applied to the simulator for oil and gas resource exploitation.

Abstract: Disclosed is a use of a liposomal pharmaceutical preparation of mitoxantrone in the preparation of a medicament for treating lymphoma, wherein the lymphoma is preferably non-Hodgkin's lymphoma, further preferably aggressive non-Hodgkin's lymphoma, more preferably diffuse large B-cell lymphoma or peripheral T-cell lymphoma, and more further preferably relapsed or refractory diffuse large B-cell lymphoma or peripheral T-cell lymphoma. The mitoxantrone liposomes are used as single anti-tumor therapeutic agent without being combined with other anti-tumor agents.

Abstract: Disclosed is a use of a liposomal pharmaceutical preparation of mitoxantrone in the preparation of a medicament for treating lymphoma, wherein the lymphoma is preferably non-Hodgkin's lymphoma, further preferably aggressive non-Hodgkin's lymphoma, more preferably diffuse large B-cell lymphoma or peripheral T-cell lymphoma, and more further preferably relapsed or refractory diffuse large B-cell lymphoma or peripheral T-cell lymphoma. The mitoxantrone liposomes are used as single anti-tumor therapeutic agent without being combined with other anti-tumor agents.

Abstract: A lotion bottle structure comprises two outer tubular cylinders adapted into a containing case assembly composed of an accommodating housing, a sealing cover, a cap body, a rotary disk, and a retaining seat wherein each outer tubular cylinder is mounted to a control unit having a push shaft, a rotary threaded tube, a collar, a positioning inner sleeve, and a base mount. A threaded rod of the push shaft is joined to an internal threaded hole of the rotary threaded tube, and the bottom of the accommodating housing is coupled to the retaining seat with the rotary disk pivotally mounted thereon to synchronically actuate both control units thereby. Therefore, lotions of different functions can be respectively filled into the two outer tubular cylinders and, via the linking mechanism of the rotary disk and the control units, simultaneously transported outwards in equivalent mixture, achieving easy carrying and convenient application thereof.

Abstract: A derotation mirror system for a common-optical-path panoramic stabilized periscope. The derotation system has a first surface-reflecting mirror, a second surface-reflecting mirror and a third surface-reflecting mirror. Through subsequent reflection of light from the surface of the first surface-reflecting mirror, the second surface-reflecting mirror, the third surface-reflecting mirror and a rotation of the entire derotation mirror system with respect to the Z-axis, the derotation is achieved. Since this invention only requires three reflections, the derotation system allows the lights with various wavebands (such as visible light, infrared light and laser beam). In addition, the derotation system manages to constrain the propagation of the output image vector and the output image vector along the same Z-axis line.

Abstract: A field-of-view switching and focusing system of a common-optical-path periscope, having an aspherical reflecting mirror system, a field-of-view driving system and a focus driving system. The field-of-view driving system and the focus driving system are located at two sides of the aspherical reflecting mirror system. The field-of-view driving system allows the aspherical reflecting mirror system to rotate, thereby, different curved faces of the aspherical reflecting mirror can reflect the incident light, so that the field of view can be switched. Further, by a linear movement of the aspherical reflecting mirror system driven along the optical path by the focus driving system, the focus fine adjustment is performed.