Abstract: A control system for multiple manipulating inputs and music outputs of wireless gaming device is provided, in which multiple wireless gaming devices can be collected in one-to-multiple manner, and the manipulating signals input from multiple wireless gaming devices can manipulate the game on the game console by a single wireless dongle under the same wireless frequency with interactive communication framework, and the game music can be transmitted to the audio interface of each of the wireless gaming devices and is played uninterruptedly, so as to possess both functions of using wireless gaming devices to manipulate game console and of transmitting game music outputted from the audio output interfaces of the wireless gaming devices to the audio output devices such as speakers or headsets.