Abstract: Provided is an anti-bacterial composition and a use thereof, specifically involving an anti-bacterial composition comprising an extract of a coffee composition and an antibiotic, and a use of the anti-bacterial composition for manufacturing an anti-bacterial medicament. The coffee composition comprises a solid content and water. The solid content comprises coffee beans and an auxiliary material. The antibiotic is selected from penicillins, cephalosporins, fluoroquinolones, tetracyclines, chloramphenicols, aminoglycosides, and a combination thereof. The ratio of the coffee composition to the antibiotic is in an amount ranging from 1.5:1 to 25000:1. The anti-bacterial composition has a better anti-bacterial effect than the antibiotic alone, and the anti-bacterial effect may also be effective against drug-resistant bacteria.

Abstract: The present invention provides a method for diagnosing pancreatitis in a canine. The method involves the following steps: First, a specimen is obtained from a canine animal. Then, a concentration of a specific biomarker in the specimen is detected, and the detected concentration is compared with a predetermined threshold value. If the biomarker concentration exceeds the threshold, the canine is determined to have an increased risk of pancreatitis. The predetermined threshold is based on the biomarker concentration observed in healthy canine animals. The biomarker can include medium-chain acylcarnitine, long-chain acylcarnitine, or a combination of both. Medium-chain acylcarnitine refers to those molecules with 6-12 carbon atoms in the acyl chain. Long-chain acylcarnitine refers to those molecules with more than 12 carbon atoms in the acyl chain. Additionally, the invention provides a method for using acylcarnitines (medium-chain and/or long-chain) as biomarkers for diagnosing pancreatitis in canines.