Patents by Inventor Kunbin Qu

Kunbin Qu has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20190256923
    Abstract: The present invention relates to biomarkers associated with breast cancer prognosis. These biomarkers include coding transcripts and their expression products, as well as non-coding transcripts, and are useful for predicting the likelihood of breast cancer recurrence in a breast cancer patient. The present invention also relates to a novel method of identifying intergenic sequences that correlate with a clinical outcome.
    Type: Application
    Filed: January 17, 2019
    Publication date: August 22, 2019
    Applicant: GENOMIC HEALTH, INC.
    Inventors: Joffre B. BAKER, Dominick SINICROPI, Robert J. PELHAM, Michael R. CRAGER, Francois COLLIN, James C. STEPHANS, Mei-Lan LIU, John D. MORLAN, Kunbin QU
  • Patent number: 10169530
    Abstract: The present invention relates to gene fusions and alternative spliced junctions associated with breast cancer. The present invention also relates to novel methods of identifying gene fusions and alternative spliced junctions in RNA sequencing data. The present invention further relates to predicting prognosis of a breast cancer patient based on the number of gene fusion events.
    Type: Grant
    Filed: November 4, 2013
    Date of Patent: January 1, 2019
    Assignee: Genomic Health, Inc.
    Inventors: Yan Ma, Kunbin Qu, Mei-Lan Liu, Ranjana Ambannavar, James Stephans
  • Publication number: 20160222463
    Abstract: The present invention relates to biomarkers associated with breast cancer prognosis. These biomarkers include coding transcripts and their expression products, as well as non-coding transcripts, and are useful for predicting the likelihood of breast cancer recurrence in a breast cancer patient, The present invention also relates to a novel method of identifying intergenic sequences that correlate with a clinical outcome.
    Type: Application
    Filed: January 29, 2016
    Publication date: August 4, 2016
    Applicant: GENOMIC HEALTH, INC.
    Inventors: Joffre B. BAKER, Dominick S. SINICROPI, Robert J. PELHAM, Michael R. CRAGER, Francois COLLIN, James C. STEPHANS, Mei-Lan LIU, John D. MORLAN, Kunbin QU
  • Publication number: 20150302143
    Abstract: The present invention relates to gene fusions and alternative spliced junctions associated with breast cancer. The present invention also relates to novel methods of identifying gene fusions and alternative spliced junctions in RNA sequencing data. The present invention further relates to predicting prognosis of a breast cancer patient based on the number of gene fusion events.
    Type: Application
    Filed: November 4, 2013
    Publication date: October 22, 2015
    Applicant: GENOMIC HEALTH, INC.
    Inventors: Yan Ma, Kunbin Qu, Mei-Lan Liu, Ranjana Ambannavar, James Stephans, John Pan
  • Publication number: 20140296085
    Abstract: The present invention relates to biomarkers associated with breast cancer prognosis. These biomarkers include coding transcripts and their expression products, as well as non-coding transcripts, and are useful for predicting the likelihood of breast cancer recurrence in a breast cancer patient, The present invention also relates to a novel method of identifying intergenic sequences that correlate with a clinical outcome.
    Type: Application
    Filed: November 2, 2012
    Publication date: October 2, 2014
    Applicant: GENOMIC HEALTH, INC.
    Inventors: Joffre B. Baker, Dominick S. Sinicropi, Robert J. Pelham, Michael R. Crager, Francois Collin, James C. Stephans, Mei-Lan Liu, John D. Morlan, Kunbin Qu
  • Patent number: 7962290
    Abstract: The invention comprises for methods of identifying pharmacophores based on the spleen tyrosine kinase (SYK) protein or fragment thereof. The invention further provides methods of identifying SYK inhibitors using pharmacophores that are identified from co-crystals of SYK and its ligands. Further, the invention comprises methods of inhibiting SYK comprising contacting the residues lining the binding site with an inhibitor compound identified from pharmacophores.
    Type: Grant
    Filed: January 9, 2007
    Date of Patent: June 14, 2011
    Assignee: Rigel Pharmaceuticals, Inc.
    Inventor: Kunbin Qu
  • Patent number: 7243112
    Abstract: This invention provides an advanced platform for the analysis of biological data that emphasizes pathway mapping and relationship inference based upon data acquired from multiple diverse sources. The platform employs a bioinformatic system that integrates data from the diverse sources, connecting related genes and proteins and inferring biological functions in the context of global cellular processes.
    Type: Grant
    Filed: June 14, 2002
    Date of Patent: July 10, 2007
    Assignee: Rigel Pharmaceuticals, Inc.
    Inventors: Kunbin Qu, Nan Lin, Yanmei Lu, Donald G. Payan
  • Publication number: 20040162852
    Abstract: This invention provides an advanced platform for the analysis of biological data that emphasizes pathway mapping and relationship inference based upon data acquired from multiple diverse sources (102). The platform employs a bioinformatic system (100) that integrates data from the diverse sources (102), connecting related genes and proteins and inferring biological functions (108) in the context of global cellular processes.
    Type: Application
    Filed: December 11, 2003
    Publication date: August 19, 2004
    Inventors: Kunbin Qu, Nan Lin, Yanmei Lu, Donald G. Payan