Patents by Inventor Kung-Ming Lu

Kung-Ming Lu has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20240050507
    Abstract: A method for preparing a Plectranthus amboinicus (PA) extract, the method comprising extracting an above-ground part of Plectranthus amboinicus with an extracting solution that comprises a solvent having a suitable polarity index, filtrating and concentration the extract thus produced, and subject the concentrated extract to a chromatographic separation process using a hydrophobic interaction chromatography resin to produce the PA extract.
    Type: Application
    Filed: October 27, 2023
    Publication date: February 15, 2024
    Applicant: Oneness Biotech Co., Ltd.
    Inventors: Yueh-Ju Wang, Kung-Ming Lu
  • Publication number: 20230414558
    Abstract: A method for alleviating radiation-induced skin disorder (e.g., radiation dermatitis), comprising administering to a subject in need thereof an effective amount of a pharmaceutical composition comprising salvigenin, and optionally cirsimaritin, rosmarinic acid, carvacrol, or a combination thereof.
    Type: Application
    Filed: June 27, 2023
    Publication date: December 28, 2023
    Inventors: Kung-Ming LU, Shyi-Gen CHEN, Jui-Ching CHEN
  • Publication number: 20230405070
    Abstract: A method for inhibiting immune responses, comprising administering to a subject in need thereof an effective amount of a pharmaceutical composition comprising salvigenin, and optionally cirsimaritin, rosmarinic acid, carvacrol, or a combination thereof.
    Type: Application
    Filed: May 26, 2023
    Publication date: December 21, 2023
    Inventors: Kung-Ming LU, Min-Liang KUO, Ching-Wen LIN
  • Patent number: 11826395
    Abstract: A method for preparing a Plectranthus amboinicus (PA) extract, the method comprising extracting an above-ground part of Plectranthus amboinicus with an extracting solution that comprises a solvent having a suitable polarity index, filtrating and concentration the extract thus produced, and subject the concentrated extract to a chromatographic separation process using a hydrophobic interaction chromatography resin to produce the PA extract.
    Type: Grant
    Filed: June 27, 2022
    Date of Patent: November 28, 2023
    Assignee: ONENESS BIOTECH CO., LTD.
    Inventors: Yueh-Ju Wang, Kung-Ming Lu
  • Publication number: 20230100100
    Abstract: Methods for treating a disorder associated with immunoglobulin E (IgE) in a subject with antibodies capable of binding to the C?mx domain of a membrane-bound IgE. The subject can be administered with at least two doses of the antibody, the two doses being at least three months apart.
    Type: Application
    Filed: September 9, 2022
    Publication date: March 30, 2023
    Applicant: Oneness Biotech Co., Ltd.
    Inventors: Kung-Ming Lu, Nien-Yi Chen, Tien-Tien Cheng
  • Publication number: 20230000941
    Abstract: A method for preparing a Plectranthus amboinicus (PA) extract, the method comprising extracting an above-ground part of Plectranthus amboinicus with an extracting solution that comprises a solvent having a suitable polarity index, filtrating and concentration the extract thus produced, and subject the concentrated extract to a chromatographic separation process using a hydrophobic interaction chromatography resin to produce the PA extract.
    Type: Application
    Filed: June 27, 2022
    Publication date: January 5, 2023
    Inventors: Yueh-Ju Wang, Kung-Ming Lu
  • Patent number: 11439682
    Abstract: Methods for treating a disorder associated with immunoglobulin E (IgE) in a subject with antibodies capable of binding to the C?mx domain of a membrane-bound IgE. The subject can be administered with at least two doses of the antibody, the two doses being at least three months apart.
    Type: Grant
    Filed: April 29, 2020
    Date of Patent: September 13, 2022
    Assignee: Oneness Biotech Co., Ltd.
    Inventors: Kung-Ming Lu, Nien-Yi Chen, Tien-Tien Cheng
  • Patent number: 11179425
    Abstract: The present invention relates to a method for activating tumor-infiltrating lymphocytes (TILs) in a subject in need, particularly by administering to the subject a fermented composition generated via fermentation of symbiotic microbiota in a medium.
    Type: Grant
    Filed: January 9, 2019
    Date of Patent: November 23, 2021
    Assignee: MICROBIO CO., LTD.
    Inventors: Kung-Ming Lu, Min-Liang Kuo, Ai-Jen Yang
  • Publication number: 20210069327
    Abstract: Combined therapy of cancer using an immune check point modulators (e.g., an immune checkpoint inhibitor) and a fermented product, which may be prepared using symbiotic microbiota.
    Type: Application
    Filed: November 19, 2020
    Publication date: March 11, 2021
    Applicant: MICROBIO CO. LTD.
    Inventor: Kung-Ming Lu
  • Patent number: 10869923
    Abstract: Combined therapy of cancer using an immune check point modulators (e.g., an immune checkpoint inhibitor) and a fermented product, which may be prepared using symbiotic microbiota.
    Type: Grant
    Filed: March 30, 2017
    Date of Patent: December 22, 2020
    Assignee: MICROBIO CO. LTD.
    Inventor: Kung-Ming Lu
  • Publication number: 20200297815
    Abstract: Methods for treating a disorder associated with immunoglobulin E (IgE) in a subject with antibodies capable of binding to the C?mx domain of a membrane-bound IgE. The subject can be administered with at least two doses of the antibody, the two doses being at least three months apart.
    Type: Application
    Filed: April 29, 2020
    Publication date: September 24, 2020
    Applicant: Oneness Biotech Co., Ltd.
    Inventors: Kung-Ming Lu, Nien-Yi Chen, Tien-Tien Cheng
  • Patent number: 10758584
    Abstract: The present invention provides a topical formulation comprising an active agent, which comprises salvigenin and optionally asiaticoside. The present invention also relates to the use of the topical formulation for the promotion of wound healing.
    Type: Grant
    Filed: July 17, 2017
    Date of Patent: September 1, 2020
    Assignee: Oneness Biotech Co. LTD
    Inventors: Jen-Wei Chen, Kung-Ming Lu
  • Publication number: 20190209623
    Abstract: The present invention relates to a method for activating tumor-infiltrating lymphocytes (TILs) in a subject in need, particularly by administering to the subject a fermented composition generated via fermentation of symbiotic microbiota in a medium.
    Type: Application
    Filed: January 9, 2019
    Publication date: July 11, 2019
    Applicant: Microbio Co., Ltd.
    Inventors: Kung-Ming Lu, Min-Liang Kuo, Ai-Jen Yang
  • Publication number: 20180015133
    Abstract: The present invention provides a topical formulation comprising an active agent, which comprises salvigenin and optionally asiaticoside. The present invention also relates to the use of the topical formulation for the promotion of wound healing.
    Type: Application
    Filed: July 17, 2017
    Publication date: January 18, 2018
    Applicant: Oneness Biotech Co. LTD
    Inventors: Jen-Wei Chen, Kung-Ming Lu
  • Publication number: 20170281760
    Abstract: Combined therapy of cancer using an immune check point modulators (e.g., an immune checkpoint inhibitor) and a fermented product, which may be prepared using symbiotic microbiota.
    Type: Application
    Filed: March 30, 2017
    Publication date: October 5, 2017
    Applicant: Microbio Co. Ltd.
    Inventor: Kung-Ming Lu
  • Patent number: 9259450
    Abstract: The present invention relates to use of a fermented soy extract as a prebiotic composition to protect beneficial bacteria in the gastrointestinal tract of an animal. Particularly, the fermented soy extract of the invention exhibits the prebiotic activity even under an antibiotic treatment. Also disclosed is combined use of an antibiotic and the fermented soy extract of the invention, which has advantages over administration of the antibiotic alone, such as decreasing the effective dose of the antibiotic and/or reducing side effects resulting from the antibiotic treatment.
    Type: Grant
    Filed: July 20, 2011
    Date of Patent: February 16, 2016
    Assignee: MICROBIO CO., LTD.
    Inventors: Ming-Hong Chuang, Cheng Der Tony Yu, Kung-Ming Lu
  • Publication number: 20120058104
    Abstract: The present invention relates to use of a fermented soy extract as a prebiotic composition to protect beneficial bacteria in the gastrointestinal tract of an animal. Particularly, the fermented soy extract of the invention exhibits the prebiotic activity even under an antibiotic treatment. Also disclosed is combined use of an antibiotic and the fermented soy extract of the invention, which has advantages over administration of the antibiotic alone, such as decreasing the effective dose of the antibiotic and/or reducing side effects resulting from the antibiotic treatment.
    Type: Application
    Filed: July 20, 2011
    Publication date: March 8, 2012
    Applicant: MICROBIO CO., LTD.
    Inventors: MING-HONG CHUANG, CHENG DER TONY YU, KUNG-MING LU
  • Publication number: 20080260695
    Abstract: The invention relates to a composition for use in the prevention and treatment of cancer. The composition includes fermented soy extract, oligomeric proanthocyanidin, epigallocatiechin gallate, spirulina, curcumin and Antrodia camphorata. The composition of the invention effectively prevents the growth of cancer cells, especially colorectal cancer, ovarian cancer, breast cancer, cervical cancer, and liver cancer.
    Type: Application
    Filed: July 16, 2007
    Publication date: October 23, 2008
    Inventor: Kung-Ming Lu
  • Publication number: 20080220100
    Abstract: This invention relates to a fermented Panax notoginseng solution and manufactured method thereof. The manufacture method comprises activating a Lactobacillus spp, fermenting a Panax notoginseng medium with the Lactobacillus spp. to form a fermented solution, and centrifuging the fermented solution to obtain a supernatant. The supernatant has anti-cancer effects.
    Type: Application
    Filed: September 5, 2007
    Publication date: September 11, 2008
    Inventor: Kung-Ming Lu
  • Patent number: 6855350
    Abstract: The present invention relates to the preparation of therapeutic compositions comprising of fermented soy extracts made with lactic acid bacteria and the optional addition of at least a yeast. The invention also relates to therapeutic uses of such extracts in promoting general health, improving the health of subjects, preventing and/or treating cancer, preventing infections, reducing the incidence of infections, treating infections, treating asthma, treating inflammation, modulating the immune system and treating immune disorders.
    Type: Grant
    Filed: July 11, 2002
    Date of Patent: February 15, 2005
    Assignee: Microbio Co., Ltd.
    Inventor: Kung-Ming Lu