Patents by Inventor Kung-Ta Lee

Kung-Ta Lee has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • ANTIMICROBIAL PEPTIDES AND METHOD OF PREVENTING OR TREATING INFECTION BY USING THE SAME
    Publication number: 20240101602
    Abstract: Provided is a peptide and method in preventing or treating infections caused by a wide spectrum of pathogens, including bacteria and fungus in hosts such as plants and animals. Methods of preventing or treating plant diseases and infection in animals are also provided.
    Type: Application
    Filed: November 24, 2021
    Publication date: March 28, 2024
    Inventors: Rita P.Y. Chen, Chiu-Ping CHENG, Chien-Chih YANG, Kung-Ta LEE, Ying-Lien CHEN, Li-Hang Hsu, Hsin-Liang CHEN, Sung CHEN
  • Whole-cell catalytic system and applications thereof
    Patent number: 11162117
    Abstract: Provided is a method of activating gene expression using a protein having 90% or more sequence identity to SEQ ID NO:45. The protein activates the expression of a gene upon induction with a medium-chain or long-chain alkane or a medium-chain or long-chain fatty acid methyl ester. Also provided is a whole-cell catalytic system regulated by a medium-chain or long-chain alkane or a medium-chain or long-chain fatty acid methyl ester. The system includes a recombinant microbial cell expressing the protein and an alkane monooxygenase. Also provided is a method of preparing a medium-chain or long-chain alkane terminal oxidation product using the whole-cell catalytic system.
    Type: Grant
    Filed: November 15, 2018
    Date of Patent: November 2, 2021
    Assignee: NATIONAL TAIWAN UNIVERSITY
    Inventors: Kung-Ta Lee, Shan-Chi Hsieh, Ching-Yeuh Su, Yu-Chen Lai
  • WHOLE-CELL CATALYTIC SYSTEM AND APPLICATIONS THEREOF
    Publication number: 20190284589
    Abstract: Provided is a method of activating gene expression using a protein having 90% or more sequence identity to SEQ ID NO:45. The protein activates the expression of a gene upon induction with a medium-chain or long-chain alkane or a medium-chain or long-chain fatty acid methyl ester. Also provided is a whole-cell catalytic system regulated by a medium-chain or long-chain alkane or a medium-chain or long-chain fatty acid methyl ester. The system includes a recombinant microbial cell expressing the protein and an alkane monooxygenase. Also provided is a method of preparing a medium-chain or long-chain alkane terminal oxidation product using the whole-cell catalytic system.
    Type: Application
    Filed: November 15, 2018
    Publication date: September 19, 2019
    Inventors: Kung-Ta Lee, Shan-Chi Hsieh, Ching-Yeuh Su, Yu-Chen Lai
  • Nattokinase for degrading and reducing amyloid fibrils—associated with alzheimer's disease, prion diseases and other amyloidoses
    Patent number: 8137666
    Abstract: A method of dissolving or disrupting pre-formed or pre-deposited amyloid fibrils and/or inhibiting amyloid formation, deposition, accumulation, or persistence in Alzheimer's disease, prion diseases and/or other amyloidoses in a mammalian subject is disclosed. In the method a therapeutically effective amount of nattokinase is administered.
    Type: Grant
    Filed: November 13, 2009
    Date of Patent: March 20, 2012
    Assignee: Academia Sinica
    Inventors: Rita P.-Y. Chen, Kung-Ta Lee
  • PROCESS FOR PREPARATION OF AGLUCONE ISOFLAVONES
    Publication number: 20100190844
    Abstract: The present invention provides a process for producing a composition containing a high concentration of aglucone isoflavones, which comprises adding glucone isoflavones to the fermentation of microorganisms which are generally recognized as safe, and can express or produce ?-glycosidase on a soy-based substrate. The present invention also provides a composition containing a high concentration of aglucone isoflavones produced in accordance with the process of the invention.
    Type: Application
    Filed: January 23, 2009
    Publication date: July 29, 2010
    Applicant: NATIONAL TAIWAN UNIVERSITY
    Inventors: Kung-Ta Lee, Ching-Jang Huang, Lun-Cheng Kuo
  • NATTOKINASE FOR DEGRADING AND REDUCING AMYLOID FIBRILS ASSOICATED WITH ALZHEIMER'S DISEASE, PRION DISEASES AND OTHER AMYLOIDOSES
    Publication number: 20100129294
    Abstract: A method of dissolving or disrupting pre-formed or pre-deposited amyloid fibrils and/or inhibiting amyloid formation, deposition, accumulation, or persistence in Alzheimer's disease, prion diseases and/or other amyloidoses in a mammalian subject is disclosed. In the method a therapeutically effective amount of nattokinase is administered.
    Type: Application
    Filed: November 13, 2009
    Publication date: May 27, 2010
    Applicant: ACADEMIA SINICA
    Inventors: RITA P.-Y. CHEN, KUNG-TA LEE