Patents by Inventor Kunihiko Yoshikawa
Kunihiko Yoshikawa has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20100322998Abstract: A neovascularization promoting composition, a granulation formation-promoting composition and a preventive or curative composition for skin ulcer, comprising a human recombinant HGF wherein five amino acid residues are deleted in the first Kringle domain thereof. The provided compositions of the present invention are useful as a drug capable of promoting granulation formation and neovascularization and being effective in tissue restoration, especially as a preventive and curative agent for skin ulcer.Type: ApplicationFiled: July 23, 2010Publication date: December 23, 2010Applicants: KRINGLE PHARMA INC.Inventors: Toshikazu Nakamura, Saho Yoshida, Kunio Matsumoto, Satoshi Itami, Kunihiko Yoshikawa
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Publication number: 20060199762Abstract: A neovascularization promoting composition, a granulation formation-promoting composition and a preventive or curative composition for skin ulcer, comprising a human recombinant HGF wherein five amino acid residues are deleted in the first Kringle domain thereof. The provided compositions of the present invention are useful as a drug capable of promoting granulation formation and neovascularization and being effective in tissue restoration, especially as a preventive and curative agent for skin ulcer.Type: ApplicationFiled: August 27, 2004Publication date: September 7, 2006Inventors: Toshikazu Nakamura, Saho Yoshida, Kunio Matsumoto, Satoshi Itami, Kunihiko Yoshikawa
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Patent number: 5464074Abstract: A braking device for a two-wheeler, such as bicycle which comprises a pair of left and right arms pivotally attached to a frame of the two-wheeler, each having on its distal end portion a brake shoe, and a spring for energizing the arms to move toward brake releasing direction. This braking device is characterized in that one of the arms is more strongly energized by the spring than the other arm is, and that a stopper is provided to restrict the extent of the movement of the strongly energized arm toward the brake releasing direction, so that, when arms are being set back to the unactuated original state, this strongly energized arm is stopped of its movement by the stopper before the other arm finally returns to its original state.Type: GrantFiled: December 30, 1993Date of Patent: November 7, 1995Assignee: Yoshikawa Mfg. Co., Ltd.Inventor: Kunihiko Yoshikawa
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Patent number: 5328001Abstract: A braking device for a two-wheeler, such as bicycle which comprises a pair of left and right arms pivotally attached to a frame of the two-wheeler, each having on its distal end portion a brake shoe, and a spring for energizing the arms to move toward brake releasing direction. This braking device is characterized in that one of the arms is more strongly energized by the spring than the other arm is, and that a stopper is provided to restrict the extent of the movement of the strongly energized arm toward the brake releasing direction, so that, when arms are being set back to the unactuated original state, this strongly energized arm is stopped of its movement by the stopper before the other arm finally returns to its original state.Type: GrantFiled: February 11, 1993Date of Patent: July 12, 1994Assignee: Yoshikawa Mfg. Co., Ltd.Inventor: Kunihiko Yoshikawa
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Patent number: 4842823Abstract: An austenitic steel having improved high-temperature strength as well as corrosion resistance is disclosed. The steel consists essentially of, by weight %:C: not more than 0.15%, Si: not more than 1.0%,Mn: not more than 10%, Cr: 20-30%,Ni: 30-55%,at least one of Mg and Ca in a total amount of 0.0010-0.0500%,Mo: 0.5-6.0% and/or W: 1.0-12.0%, whereinMo(%)+1/2W(%)=0.5-6.0(%),B: 0-0.0100%, Zr: 0-0.200%,Ti: 0-0.30%, Nb: 0-1.00%,V: 0-1.00%, andbalance: Fe and incidental impurities, of which impurities P, S, and Al are restricted to:P: not more than 0.020%,S: not more than 0.010%, andAl: not more than 0.030%,P (%)+S (%)+Al (%) being less than 0.050%.Type: GrantFiled: August 14, 1987Date of Patent: June 27, 1989Assignee: Sumitomo Metal Industries, Ltd.Inventors: Yoshiatsu Sawaragi, Kunihiko Yoshikawa, Hiroshi Teranishi
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Patent number: 4799972Abstract: A high-strength high-Cr ferritic, heat-resistant steel exhibiting improved high-temperature, long-term creep strength and a process for producing the same are disclosed. The steel consists essentially of, by weight %:C: not more than 0.2%,Si: not more than 1.0%,Mn: 0.1-1.5%,P: not more than 0.03%,S: not more than 0.03%,Ni: not more than 1.0%,Cr: 5.0-15%,Mo: 0.02-3.0%,W: not more than 4.0%,sol. Al: 0.005-0.04%,N: not more than 0.07%,at least one of V: 0.01-0.4% and Nb: 0.01-0.3%,B: 0-0.02%,at least one of Ca, Ti, Zr, Y, La, and Ce: 0-0.2%, andthe balance Fe and incidental impurities, the A.sub.cl point defined by Formula (1) below being 820.degree. or higher.A.sub.cl (.degree.C.)=765-500 C-450N+30Si-25 Mn+25 Mo+15W+11Cr+50V+30Nb-30Ni+30 sol. Al (weight %).Type: GrantFiled: October 10, 1986Date of Patent: January 24, 1989Assignees: Sumitomo Metal Industries, Ltd., Mitsubishi Jukogyo Kabushiki KaishaInventors: Fujimitsu Masuyama, Takashi Daikoku, Hisao Haneda, Kunihiko Yoshikawa, Hiroshi Teranishi, Atsuro Iseda
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Patent number: 4652315Abstract: A precipitation-hardening Ni-base alloy exhibiting improved resistance to corrosion under a corrosive environment containing at least one of hydrogen sulfide, carbon dioxide and chloride ions and method of producing the same are disclosed. The alloy is of the .gamma."-phase, or (.gamma.'+.gamma.")-phase precipitation hardening type in which Ti is restricted to less than 0.40% and is comprised of:C: not greater than 0.050%,Si: not greater than 0.50%,Mn: not greater than 2.0%,Ni: 40-60%,Cr: 18-27%,Ti: less than 0.40%,Mo: 2.5-5.5% and/or W: not greater than 11%, t 2.5%.ltoreq.Mo+1/2W.ltoreq.5.5%,Al: not greater than than 2.0%,Nb: 2.5-6.0% and/or Ta: not greater than 2.0%, 2.5%.ltoreq.Nb+1/2Ta.ltoreq.6.0%.Type: GrantFiled: June 19, 1984Date of Patent: March 24, 1987Assignee: Sumitomo Metal Industries, Ltd.Inventors: Masaaki Igarashi, Yasutaka Okada, Kunihiko Yoshikawa, Takeo Kudo
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Patent number: 4421571Abstract: A process for manufacturing high strength deep well casing, tubing, and drill pipes, which have improved resistance to stress corrosion cracking is disclosed. The process comprises the steps of preparing an alloy composition which is:______________________________________ C .ltoreq.0.05% Si .ltoreq.1.0% Mn .ltoreq.2.0% P .ltoreq.0.030% S .ltoreq.0.005% N 0-0.30% Ni 25-60% Cr 15-35% Mo 0-12% W 0-24% Cr (%) + 10Mo (%) + 5W (%) .gtoreq. 50% 1.5% .ltoreq. Mo (%) + 1/2W (%) .ltoreq. 12% Cu 0-2.0% Co 0-2.0% Rare Earths 0-0.10% Y 0-0.20% Mg 0-0.10% Ti 0-0.5% Ca 0-0.10% and incidental impurities balance; ______________________________________applying, after hot working, the solid solution treatment to the alloy at a temperature of from the lower limit temperature (.degree.C.) defined by the following empirical formula: 260 log C(%)+1300 to the upper limit temperature (.degree.C.Type: GrantFiled: June 17, 1982Date of Patent: December 20, 1983Assignee: Sumitomo Metal Industries, Ltd.Inventors: Takeo Kudo, Yasutaka Okada, Taishi Moroishi, Akio Ikeda, Hiroo Ohtani, Kunihiko Yoshikawa
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Patent number: 4400211Abstract: An alloy useful for manufacturing high strength deep well casing, tubing and drill pipes for use in oil-well operations is disclosed. The alloy exhibits improved resistance to stress corrosion cracking in the H.sub.2 S-CO.sub.2 -Cl.sup.- environment, which comprises the following alloy composition:______________________________________ C: .ltoreq.0.1% Si: .ltoreq.1.0% Mn: .ltoreq.2.0% P: .ltoreq.0.030% S: .ltoreq.0.005% N: 0-0.30% Ni: 30-60% Cr: 15-35% Mo: 0-12% W: 0-24% Cr(%) + 10Mo(%) + 5W(%) .gtoreq. 110% 7.5% .ltoreq. Mo(%) + 1/2W(%) .ltoreq. 12% Cu: 0-2.0% Co: 0-2.0% rare earths: 0-0.10% Y: 0-0.20% Mg: 0-0.10% Ca: 0-0.10% one or more of Nb, Ti, Ta, Zr and V in the total amount of 0.5-4.0%, if necessary Fe and incidental impurities: balance.Type: GrantFiled: June 1, 1982Date of Patent: August 23, 1983Assignee: Sumitomo Metal Industries, Ltd.Inventors: Takeo Kudo, Yasutaka Okada, Taishi Moroishi, Akio Ikeda, Hiroo Ohtani, Kunihiko Yoshikawa
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Patent number: 4400210Abstract: An alloy useful for manufacturing high strength deep well casing, tubing and drill pipes for use in oil-well operations is disclosed. The alloy exhibits improved resistance to stress corrosion cracking in the H.sub.2 S--CO.sub.2 --Cl.sup.- -environment, which comprises the following alloy composition:______________________________________ C: .ltoreq.0.1% Si: .ltoreq.1.0% Mn: .ltoreq.2.0% P: .ltoreq.0.030% S: .ltoreq.0.005% N: 0-0.30% Ni: 25-60% Cr: 22.5-35% Mo: 0-7.5% (excl.) W: 0-15% (excl.) Cr (%) + 10Mo (%) + 5W (%) .gtoreq. 70% 3.5% .ltoreq. Mo (%) + 1/2W (%) < 7.5% Cu: 0-2.0% Co: 0-2.0% Rare earths: 0-0.10% Y: 0-0.20% Mg: 0-0.10% Ca: 0-0.10% ______________________________________one or more of Nb, Ti, Ta, Zr and V in the total amount of 0.5-4.0%, if necessary,Fe and incidental impurities: balance.Type: GrantFiled: June 1, 1982Date of Patent: August 23, 1983Assignee: Sumitomo Metal Industries, Ltd.Inventors: Takeo Kudo, Yasutaka Okada, Taishi Moroishi, Akio Ikeda, Hiroo Ohtani, Kunihiko Yoshikawa
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Patent number: 4400209Abstract: An alloy useful for manufacturing high strength deep well casing, tubing and drill pipes for use in oil-well operations is disclosed. The alloy exhibits improved resistance to stress corrosion cracking in the H.sub.2 S--CO.sub.2 --Cl.sup.- environment, which comprises the following alloy composition:______________________________________ C: .ltoreq. 0.1% Si: .ltoreq. 1.0% Mn: .ltoreq. 2.0% P: .ltoreq. 0.030% S: .ltoreq. 0.005% N: 0-0.30% Ni: 25-60% Cr: 22.5-40% Mo: 0-3.5% (excl.) W: 0-7% (excl.) Cr (%) + 10Mo (%) + 5W (%) .gtoreq. 50%, 1.0% .ltoreq. Mo (%) + 1/2W (%) < 3.5% Cu: 0-2.0% Co: 0-2.0% Rare earths: 0-0.10% Y: 0-0.20% Mg: 0-0.10% Ca: 0-0.10% one or more of Nb, Ti, Ta, Zr and V in the total amount of 0.5-4.0, if necessary, Fe and incidental impurities: balance.Type: GrantFiled: June 1, 1982Date of Patent: August 23, 1983Assignee: Sumitomo Metal Industries, Ltd.Inventors: Takeo Kudo, Yasutaka Okada, Taishi Moroishi, Akio Ikeda, Hiroo Ohtani, Kunihiko Yoshikawa
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Patent number: 4400349Abstract: An alloy useful for manufacturing high strength oil-well casing, tubing and drill pipes for use in oil-well operations is disclosed. The alloy exhibits improved resistance to stress corrosion cracking in the H.sub.2 S--CO.sub.2 --Cl.sup.- environment, which comprises the following alloy composition:______________________________________ C: .ltoreq. 0.1% Si: .ltoreq. 1.0% Mn: 3-20% P: .ltoreq. 0.030% S: .ltoreq. 0.005% N: 0-0.30% sol. Al .ltoreq. 0.5% Ni: 20-60% Cr: 15-35% Mo: 0-12% W: 0-24% Cr(%) + 10 Mo(%) + 5 W(%) .gtoreq. 50% 1/2 Mn(%) + Ni(%) .gtoreq. 25% 1.5% .ltoreq. Mo(%) + 1/2 W(%) .ltoreq. 12% Cu: 0-2.0% Co: 0-2.0% Rare Earths: 0-0.10% Y: 0-0.20% Mg: 0-0.10% Ti: 0-0.5% Ca: 0-0.10% Fe and incidental impurities: balance.Type: GrantFiled: June 17, 1982Date of Patent: August 23, 1983Assignee: Sumitomo Metal Industries, Ltd.Inventors: Takeo Kudo, Yasutaka Okada, Taishi Moroishi, Akio Ikeda, Hiroo Ohtani, Kunihiko Yoshikawa
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Patent number: 4244235Abstract: Apparatus for attaching a stay for a brake lever to a handle bar of a bicycle in which a non-ferrous metal or synthetic resin stay pivotably supports a brake lever through a pivot shaft by a fastening band mounted in a cavity portion formed in the bottom of the stay. A spacer is mounted within the cavity portion and has first support elements for abutting against the handle bar and second support elements for engaging the pivot shaft such that when the band is secured to the pivot shaft frictional engagement is obtained between the first supporting elements and the handle bar and the stay becomes secured to the handle bar through the spacer.Type: GrantFiled: October 25, 1978Date of Patent: January 13, 1981Assignee: Kabushiki Kaisha Yoshikawa SeisakushoInventor: Kunihiko Yoshikawa
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Patent number: 4143745Abstract: A holder for pulling-up wire in a center pull type caliper brake for a bicycle. The holder has an upper portion with a wire screw and a hook portion at the lower portion for hooking a pulling-up wire. A pair of finger members projecting from the holder member on both sides of the hook portion and a guide member serve to pull up wire from the hook portion.Type: GrantFiled: October 5, 1977Date of Patent: March 13, 1979Assignee: Kabushiki Kaisha Yoshikawa SeisakushoInventor: Kunihiko Yoshikawa