Patents by Inventor Kunihiko Yoshikawa

Kunihiko Yoshikawa has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20100322998
    Abstract: A neovascularization promoting composition, a granulation formation-promoting composition and a preventive or curative composition for skin ulcer, comprising a human recombinant HGF wherein five amino acid residues are deleted in the first Kringle domain thereof. The provided compositions of the present invention are useful as a drug capable of promoting granulation formation and neovascularization and being effective in tissue restoration, especially as a preventive and curative agent for skin ulcer.
    Type: Application
    Filed: July 23, 2010
    Publication date: December 23, 2010
    Applicants: KRINGLE PHARMA INC.
    Inventors: Toshikazu Nakamura, Saho Yoshida, Kunio Matsumoto, Satoshi Itami, Kunihiko Yoshikawa
  • Publication number: 20060199762
    Abstract: A neovascularization promoting composition, a granulation formation-promoting composition and a preventive or curative composition for skin ulcer, comprising a human recombinant HGF wherein five amino acid residues are deleted in the first Kringle domain thereof. The provided compositions of the present invention are useful as a drug capable of promoting granulation formation and neovascularization and being effective in tissue restoration, especially as a preventive and curative agent for skin ulcer.
    Type: Application
    Filed: August 27, 2004
    Publication date: September 7, 2006
    Inventors: Toshikazu Nakamura, Saho Yoshida, Kunio Matsumoto, Satoshi Itami, Kunihiko Yoshikawa
  • Patent number: 5464074
    Abstract: A braking device for a two-wheeler, such as bicycle which comprises a pair of left and right arms pivotally attached to a frame of the two-wheeler, each having on its distal end portion a brake shoe, and a spring for energizing the arms to move toward brake releasing direction. This braking device is characterized in that one of the arms is more strongly energized by the spring than the other arm is, and that a stopper is provided to restrict the extent of the movement of the strongly energized arm toward the brake releasing direction, so that, when arms are being set back to the unactuated original state, this strongly energized arm is stopped of its movement by the stopper before the other arm finally returns to its original state.
    Type: Grant
    Filed: December 30, 1993
    Date of Patent: November 7, 1995
    Assignee: Yoshikawa Mfg. Co., Ltd.
    Inventor: Kunihiko Yoshikawa
  • Patent number: 5328001
    Abstract: A braking device for a two-wheeler, such as bicycle which comprises a pair of left and right arms pivotally attached to a frame of the two-wheeler, each having on its distal end portion a brake shoe, and a spring for energizing the arms to move toward brake releasing direction. This braking device is characterized in that one of the arms is more strongly energized by the spring than the other arm is, and that a stopper is provided to restrict the extent of the movement of the strongly energized arm toward the brake releasing direction, so that, when arms are being set back to the unactuated original state, this strongly energized arm is stopped of its movement by the stopper before the other arm finally returns to its original state.
    Type: Grant
    Filed: February 11, 1993
    Date of Patent: July 12, 1994
    Assignee: Yoshikawa Mfg. Co., Ltd.
    Inventor: Kunihiko Yoshikawa
  • Patent number: 4842823
    Abstract: An austenitic steel having improved high-temperature strength as well as corrosion resistance is disclosed. The steel consists essentially of, by weight %:C: not more than 0.15%, Si: not more than 1.0%,Mn: not more than 10%, Cr: 20-30%,Ni: 30-55%,at least one of Mg and Ca in a total amount of 0.0010-0.0500%,Mo: 0.5-6.0% and/or W: 1.0-12.0%, whereinMo(%)+1/2W(%)=0.5-6.0(%),B: 0-0.0100%, Zr: 0-0.200%,Ti: 0-0.30%, Nb: 0-1.00%,V: 0-1.00%, andbalance: Fe and incidental impurities, of which impurities P, S, and Al are restricted to:P: not more than 0.020%,S: not more than 0.010%, andAl: not more than 0.030%,P (%)+S (%)+Al (%) being less than 0.050%.
    Type: Grant
    Filed: August 14, 1987
    Date of Patent: June 27, 1989
    Assignee: Sumitomo Metal Industries, Ltd.
    Inventors: Yoshiatsu Sawaragi, Kunihiko Yoshikawa, Hiroshi Teranishi
  • Patent number: 4799972
    Abstract: A high-strength high-Cr ferritic, heat-resistant steel exhibiting improved high-temperature, long-term creep strength and a process for producing the same are disclosed. The steel consists essentially of, by weight %:C: not more than 0.2%,Si: not more than 1.0%,Mn: 0.1-1.5%,P: not more than 0.03%,S: not more than 0.03%,Ni: not more than 1.0%,Cr: 5.0-15%,Mo: 0.02-3.0%,W: not more than 4.0%,sol. Al: 0.005-0.04%,N: not more than 0.07%,at least one of V: 0.01-0.4% and Nb: 0.01-0.3%,B: 0-0.02%,at least one of Ca, Ti, Zr, Y, La, and Ce: 0-0.2%, andthe balance Fe and incidental impurities, the A.sub.cl point defined by Formula (1) below being 820.degree. or higher.A.sub.cl (.degree.C.)=765-500 C-450N+30Si-25 Mn+25 Mo+15W+11Cr+50V+30Nb-30Ni+30 sol. Al (weight %).
    Type: Grant
    Filed: October 10, 1986
    Date of Patent: January 24, 1989
    Assignees: Sumitomo Metal Industries, Ltd., Mitsubishi Jukogyo Kabushiki Kaisha
    Inventors: Fujimitsu Masuyama, Takashi Daikoku, Hisao Haneda, Kunihiko Yoshikawa, Hiroshi Teranishi, Atsuro Iseda
  • Patent number: 4652315
    Abstract: A precipitation-hardening Ni-base alloy exhibiting improved resistance to corrosion under a corrosive environment containing at least one of hydrogen sulfide, carbon dioxide and chloride ions and method of producing the same are disclosed. The alloy is of the .gamma."-phase, or (.gamma.'+.gamma.")-phase precipitation hardening type in which Ti is restricted to less than 0.40% and is comprised of:C: not greater than 0.050%,Si: not greater than 0.50%,Mn: not greater than 2.0%,Ni: 40-60%,Cr: 18-27%,Ti: less than 0.40%,Mo: 2.5-5.5% and/or W: not greater than 11%, t 2.5%.ltoreq.Mo+1/2W.ltoreq.5.5%,Al: not greater than than 2.0%,Nb: 2.5-6.0% and/or Ta: not greater than 2.0%, 2.5%.ltoreq.Nb+1/2Ta.ltoreq.6.0%.
    Type: Grant
    Filed: June 19, 1984
    Date of Patent: March 24, 1987
    Assignee: Sumitomo Metal Industries, Ltd.
    Inventors: Masaaki Igarashi, Yasutaka Okada, Kunihiko Yoshikawa, Takeo Kudo
  • Patent number: 4421571
    Abstract: A process for manufacturing high strength deep well casing, tubing, and drill pipes, which have improved resistance to stress corrosion cracking is disclosed. The process comprises the steps of preparing an alloy composition which is:______________________________________ C .ltoreq.0.05% Si .ltoreq.1.0% Mn .ltoreq.2.0% P .ltoreq.0.030% S .ltoreq.0.005% N 0-0.30% Ni 25-60% Cr 15-35% Mo 0-12% W 0-24% Cr (%) + 10Mo (%) + 5W (%) .gtoreq. 50% 1.5% .ltoreq. Mo (%) + 1/2W (%) .ltoreq. 12% Cu 0-2.0% Co 0-2.0% Rare Earths 0-0.10% Y 0-0.20% Mg 0-0.10% Ti 0-0.5% Ca 0-0.10% and incidental impurities balance; ______________________________________applying, after hot working, the solid solution treatment to the alloy at a temperature of from the lower limit temperature (.degree.C.) defined by the following empirical formula: 260 log C(%)+1300 to the upper limit temperature (.degree.C.
    Type: Grant
    Filed: June 17, 1982
    Date of Patent: December 20, 1983
    Assignee: Sumitomo Metal Industries, Ltd.
    Inventors: Takeo Kudo, Yasutaka Okada, Taishi Moroishi, Akio Ikeda, Hiroo Ohtani, Kunihiko Yoshikawa
  • Patent number: 4400211
    Abstract: An alloy useful for manufacturing high strength deep well casing, tubing and drill pipes for use in oil-well operations is disclosed. The alloy exhibits improved resistance to stress corrosion cracking in the H.sub.2 S-CO.sub.2 -Cl.sup.- environment, which comprises the following alloy composition:______________________________________ C: .ltoreq.0.1% Si: .ltoreq.1.0% Mn: .ltoreq.2.0% P: .ltoreq.0.030% S: .ltoreq.0.005% N: 0-0.30% Ni: 30-60% Cr: 15-35% Mo: 0-12% W: 0-24% Cr(%) + 10Mo(%) + 5W(%) .gtoreq. 110% 7.5% .ltoreq. Mo(%) + 1/2W(%) .ltoreq. 12% Cu: 0-2.0% Co: 0-2.0% rare earths: 0-0.10% Y: 0-0.20% Mg: 0-0.10% Ca: 0-0.10% one or more of Nb, Ti, Ta, Zr and V in the total amount of 0.5-4.0%, if necessary Fe and incidental impurities: balance.
    Type: Grant
    Filed: June 1, 1982
    Date of Patent: August 23, 1983
    Assignee: Sumitomo Metal Industries, Ltd.
    Inventors: Takeo Kudo, Yasutaka Okada, Taishi Moroishi, Akio Ikeda, Hiroo Ohtani, Kunihiko Yoshikawa
  • Patent number: 4400210
    Abstract: An alloy useful for manufacturing high strength deep well casing, tubing and drill pipes for use in oil-well operations is disclosed. The alloy exhibits improved resistance to stress corrosion cracking in the H.sub.2 S--CO.sub.2 --Cl.sup.- -environment, which comprises the following alloy composition:______________________________________ C: .ltoreq.0.1% Si: .ltoreq.1.0% Mn: .ltoreq.2.0% P: .ltoreq.0.030% S: .ltoreq.0.005% N: 0-0.30% Ni: 25-60% Cr: 22.5-35% Mo: 0-7.5% (excl.) W: 0-15% (excl.) Cr (%) + 10Mo (%) + 5W (%) .gtoreq. 70% 3.5% .ltoreq. Mo (%) + 1/2W (%) < 7.5% Cu: 0-2.0% Co: 0-2.0% Rare earths: 0-0.10% Y: 0-0.20% Mg: 0-0.10% Ca: 0-0.10% ______________________________________one or more of Nb, Ti, Ta, Zr and V in the total amount of 0.5-4.0%, if necessary,Fe and incidental impurities: balance.
    Type: Grant
    Filed: June 1, 1982
    Date of Patent: August 23, 1983
    Assignee: Sumitomo Metal Industries, Ltd.
    Inventors: Takeo Kudo, Yasutaka Okada, Taishi Moroishi, Akio Ikeda, Hiroo Ohtani, Kunihiko Yoshikawa
  • Patent number: 4400209
    Abstract: An alloy useful for manufacturing high strength deep well casing, tubing and drill pipes for use in oil-well operations is disclosed. The alloy exhibits improved resistance to stress corrosion cracking in the H.sub.2 S--CO.sub.2 --Cl.sup.- environment, which comprises the following alloy composition:______________________________________ C: .ltoreq. 0.1% Si: .ltoreq. 1.0% Mn: .ltoreq. 2.0% P: .ltoreq. 0.030% S: .ltoreq. 0.005% N: 0-0.30% Ni: 25-60% Cr: 22.5-40% Mo: 0-3.5% (excl.) W: 0-7% (excl.) Cr (%) + 10Mo (%) + 5W (%) .gtoreq. 50%, 1.0% .ltoreq. Mo (%) + 1/2W (%) < 3.5% Cu: 0-2.0% Co: 0-2.0% Rare earths: 0-0.10% Y: 0-0.20% Mg: 0-0.10% Ca: 0-0.10% one or more of Nb, Ti, Ta, Zr and V in the total amount of 0.5-4.0, if necessary, Fe and incidental impurities: balance.
    Type: Grant
    Filed: June 1, 1982
    Date of Patent: August 23, 1983
    Assignee: Sumitomo Metal Industries, Ltd.
    Inventors: Takeo Kudo, Yasutaka Okada, Taishi Moroishi, Akio Ikeda, Hiroo Ohtani, Kunihiko Yoshikawa
  • Patent number: 4400349
    Abstract: An alloy useful for manufacturing high strength oil-well casing, tubing and drill pipes for use in oil-well operations is disclosed. The alloy exhibits improved resistance to stress corrosion cracking in the H.sub.2 S--CO.sub.2 --Cl.sup.- environment, which comprises the following alloy composition:______________________________________ C: .ltoreq. 0.1% Si: .ltoreq. 1.0% Mn: 3-20% P: .ltoreq. 0.030% S: .ltoreq. 0.005% N: 0-0.30% sol. Al .ltoreq. 0.5% Ni: 20-60% Cr: 15-35% Mo: 0-12% W: 0-24% Cr(%) + 10 Mo(%) + 5 W(%) .gtoreq. 50% 1/2 Mn(%) + Ni(%) .gtoreq. 25% 1.5% .ltoreq. Mo(%) + 1/2 W(%) .ltoreq. 12% Cu: 0-2.0% Co: 0-2.0% Rare Earths: 0-0.10% Y: 0-0.20% Mg: 0-0.10% Ti: 0-0.5% Ca: 0-0.10% Fe and incidental impurities: balance.
    Type: Grant
    Filed: June 17, 1982
    Date of Patent: August 23, 1983
    Assignee: Sumitomo Metal Industries, Ltd.
    Inventors: Takeo Kudo, Yasutaka Okada, Taishi Moroishi, Akio Ikeda, Hiroo Ohtani, Kunihiko Yoshikawa
  • Patent number: 4244235
    Abstract: Apparatus for attaching a stay for a brake lever to a handle bar of a bicycle in which a non-ferrous metal or synthetic resin stay pivotably supports a brake lever through a pivot shaft by a fastening band mounted in a cavity portion formed in the bottom of the stay. A spacer is mounted within the cavity portion and has first support elements for abutting against the handle bar and second support elements for engaging the pivot shaft such that when the band is secured to the pivot shaft frictional engagement is obtained between the first supporting elements and the handle bar and the stay becomes secured to the handle bar through the spacer.
    Type: Grant
    Filed: October 25, 1978
    Date of Patent: January 13, 1981
    Assignee: Kabushiki Kaisha Yoshikawa Seisakusho
    Inventor: Kunihiko Yoshikawa
  • Patent number: 4143745
    Abstract: A holder for pulling-up wire in a center pull type caliper brake for a bicycle. The holder has an upper portion with a wire screw and a hook portion at the lower portion for hooking a pulling-up wire. A pair of finger members projecting from the holder member on both sides of the hook portion and a guide member serve to pull up wire from the hook portion.
    Type: Grant
    Filed: October 5, 1977
    Date of Patent: March 13, 1979
    Assignee: Kabushiki Kaisha Yoshikawa Seisakusho
    Inventor: Kunihiko Yoshikawa