Abstract: A syringe assembly includes a first syringe having a first syringe outer cylinder filled with a first liquid, and a first gasket; a second syringe having a second syringe outer cylinder filled with a second liquid, and a second gasket; and a pusher assembly which performs a pushing operation of collectively moving the first and second gaskets. The pusher assembly includes a first pusher having a distal portion connected to the first gasket; a second pusher branching from the first pusher, extending distally, having a distal portion connected to the second gasket; and an operation section which is provided on a proximal-side extension line of the first pusher and is operated for the pushing operation.

Abstract: To provide a means which can suppress a decrease in the effect of preventing enzyme leakage and a decrease in adhesive strength (pressure resistance) when attaching body tissues by using a tissue adhesive containing a protein. A method for attaching body tissues by applying a tissue adhesive containing a protein to the body tissues includes a heat treatment of the protein simultaneously with or after applying the tissue adhesive to the body tissues.

Abstract: There is provided an applicator including: a first liquid flow path through which a first liquid containing fibrinogen passes; a second liquid flow path through which a second liquid containing thrombin passes; a confluence section in which the first liquid and the second liquid merge with each other to form a mixed liquid; and a gas flow path through which a gas for jetting the mixed liquid passes. At least part of a wall portion defining the confluence section is composed of a gas-permeable membrane that is impermeable to the mixed liquid and permeable to the gas.

Abstract: There is provided an applicator for ejecting together with a gas a mixed liquid obtained by mixing a first liquid and a second liquid which are different from each other in composition. The applicator includes a first liquid flow path through which the first liquid flows; a second liquid flow path through which the second liquid flows; a gas flow path through which the gas flows; a confluence section in which the first liquid and the second liquid merge; and a backflow preventing section that prevents backflow of the first liquid and prevents backflow of the second liquid.

Abstract: A syringe assembly includes a first syringe having a syringe outer cylinder filled with a first liquid, and a gasket; a second syringe having a syringe outer cylinder filled with a second liquid, and a gasket; and a pusher assembly which performs a pushing operation of collectively moving the gaskets and. The pusher assembly includes a first pusher having a distal portion connected to the gasket; a second pusher branching from the first pusher, extending distally, having a distal portion connected to the gasket; and an operation section which is provided on a proximal-side extension line of the first pusher and is operated for the pushing operation.