Abstract: The present invention relates to a RET fusion gene such as a CCDC6-RET fusion gene as a biomarker to monitor the activity of the compound 3-Z-[1-(4-(N-((4-methyl-piperazin-1-yl)-methylcarbonyl)-N-methyl-amino)-anilino)-1-phenyl-methylene]-6-methoxycarbonyl-2-indolinone or a pharmaceutically acceptable salt thereof, and especially its monoethanesulphonate salt form, when used alone or optionally in combination with further pharmaceutically active ingredients and/or further treatments. The present invention also relates to specific uses of said specific compound in the treatment of cancers.

Abstract: A fuel cell system, control method and current measuring device for a power unit are disclosed. The fuel cell system includes a fuel cell having local areas, a current measuring device associated with at least one of the local areas to measure localized current related to a specified operating characteristic, and a control section for diagnosing an operating condition of the fuel cell in response to localized current to enable optimum control of the fuel cell depending upon a specified operating characteristic determined by localized current. The control method controls the operating condition of the fuel cell in response to localized current indicative of the specified operating characteristic of the fuel cell. The current measuring device includes an electrical conductor formed with a recessed portion, a localized current conductor received in the recessed portion, and a current sensor for detecting current flowing across the localized current conductor.

Abstract: A fuel cell system includes a fuel cell constructed by plural stacked cells, a circulation path through which a thermal medium is circulated into each cell, a heater for heating the thermal medium, a bypass path through which the thermal medium is circulated into a part of each cell while bypassing the other part thereof, and a flow control valve for controlling a flow amount of the thermal medium circulated in the bypass path. The thermal medium can be circulated into only the part of each cell in a warm-up operation, so that the part of each cell is collectively heated. An amount of the thermal medium circulated into the other part of each cell is controlled, so that all of each cell is finally warmed up in the warm-up operation.

Abstract: Portable storage cases comprising a base and a lid which is automatically movable by a damped, spring-biased lid mechanism. Upon actuation of a release, the lid automatically moves from a closed position to an open position. A display support is pivotally movable with respect to the base and is moved during at least part of the time that the lid is moving from the closed to the open position. The display support is adapted to releasably support at least one item and, if desired, supports a plurality of items. In preferred embodiments, movement of the display support only commences after the lid has moved for some predetermined time, distance or angle.

Abstract: A fuel cell system includes a windshield washer container 1 storing windshield washer fluid, a permeable membrane unit 2 provided inside the windshield washer container 1, and a fuel cell 11. The permeable membrane unit 2 has the capability of extracting methanol from the windshield washer fluid. The extracted methanol is directly used as the fuel for the fuel cell 11. The windshield washer container 1 has the size comparable with or less than that of a conventional windshield washer container.

Abstract: A measuring method first calculates the conductivity of an electrolyte membrane based on measured output voltage and output current of a fuel cell. The water content of an oxidant channel as an index of present water content (PWC) of the fuel cell is calculated based on the calculated conductivity and the other measured physical quantities of the fuel cell. Further the method calculates the water content of the oxidant channel after the inside of the fuel cell reaches a steady state as an index of future water content (FWC) using the measured physical quantities. The PWC index and FWC index are compared, and it is finally determined, based on the result of the comparison and the difference between the previous and present values of the conductivity, whether the water content of the fuel cell is short or excessive at the present time.

Abstract: In a fuel cell system, a fuel cell includes plural stacked cells, a circulation passage for circulating a thermal medium to the fuel cell. The fuel cell has therein a plurality of thermal medium passages through which the thermal medium flows, and the thermal medium passages are provided such that the thermal medium from the circulation passage independently flows through the thermal medium passages. The thermal medium passages in the fuel cell have inlet portions from which the thermal medium is introduced, and outlet portions from which the thermal medium is discharged. In the fuel cell system, at least one-side portions among the inlet portions and the outlet portions are provided independently. Accordingly, a circulation area of the thermal medium in the fuel cell can be selectively changed, and a part of the fuel cell can be effectively heated to generate electrical power in this part.

Abstract: A fuel cell system includes a fuel cell constructed by plural stacked cells, a circulation path through which a thermal medium is circulated into each cell, a heater for heating the thermal medium, a bypass path through which the thermal medium is circulated into a part of each cell while bypassing the other part thereof, and a flow control valve for controlling a flow amount of the thermal medium circulated in the bypass path. The thermal medium can be circulated into only the part of each cell in a warm-up operation, so that the part of each cell is collectively heated. An amount of the thermal medium circulated into the other part of each cell is controlled, so that all of each cell is finally warmed up in the warm-up operation.

Abstract: A fuel cell system includes a fuel cell constructed by plural stacked cells, a circulation path through which a thermal medium is circulated into each cell, a heater for heating the thermal medium, a bypass path through which the thermal medium is circulated into a part of each cell while bypassing the other part thereof, and a flow control valve for controlling a flow amount of the thermal medium circulated in the bypass path. The thermal medium can be circulated into only the part of each cell in a warm-up operation, so that the part of each cell is collectively heated. An amount of the thermal medium circulated into the other part of each cell is controlled, so that all of each cell is finally warmed up in the warm-up operation.

Abstract: A fuel cell system includes a windshield washer container 1 storing windshield washer fluid, a permeable membrane unit 2 provided inside the windshield washer container 1, and a fuel cell 11. The permeable membrane unit 2 has the capability of extracting methanol from the windshield washer fluid. The extracted methanol is directly used as the fuel for the fuel cell 11. The windshield washer container 1 has the size comparable with or less than that of a conventional windshield washer container.

Abstract: A fuel cell system, control method and current measuring device for a power unit are disclosed. The fuel cell system includes a fuel cell having local areas, a current measuring device associated with at least one of the local areas to measure localized current related to a specified operating characteristic, and a control section for diagnosing an operating condition of the fuel cell in response to localized current to enable optimum control of the fuel cell depending upon a specified operating characteristic determined by localized current. The control method controls the operating condition of the fuel cell in response to localized current indicative of the specified operating characteristic of the fuel cell. The current measuring device includes an electrical conductor formed with a recessed portion, a localized current conductor received in the recessed portion, and a current sensor for detecting current flowing across the localized current conductor.

Abstract: A fuel cell system includes a heat-generation amount detection device for detecting a heat generation amount in a fuel cell, and an evaporation amount controller for controlling an evaporation amount of water in the fuel cell based on the detected heat generation amount. The heat generation amount is detected based on an output electric power of the fuel cell, an output current thereof or a temperature thereof. The evaporation amount of water in the fuel cell is controlled by adjusting at least one humidification amount of hydrogen and oxygen to be supplied to the fuel cell, or by adjusting at least one flow amount of hydrogen and oxygen to be supplied to the fuel cell.

Abstract: In a fuel cell system, a fuel cell includes plural stacked cells, a circulation passage for circulating a thermal medium to the fuel cell. The fuel cell has therein a plurality of thermal medium passages through which the thermal medium flows, and the thermal medium passages are provided such that the thermal medium from the circulation passage independently flows through the thermal medium passages. The thermal medium passages in the fuel cell have inlet portions from which the thermal medium is introduced, and outlet portions from which the thermal medium is discharged. In the fuel cell system, at least one-side portions among the inlet portions and the outlet portions are provided independently. Accordingly, a circulation area of the thermal medium in the fuel cell can be selectively changed, and a part of the fuel cell can be effectively heated to generate electrical power in this part.