Patents by Inventor Kunitake Abe
Kunitake Abe has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20230301514Abstract: A device for measuring an intraocular pressure that includes: a pressure sensor configured to measure the intraocular pressure; an ultrasonic transducer electrically coupled to the pressure sensor and configured to receive ultrasonic waves and emit ultrasonic backscatter encoding a pressure measured by the pressure sensor, and a substrate attached to the pressure sensor and the ultrasonic transducer, and configured to interface a surface on or within an eye.Type: ApplicationFiled: August 10, 2021Publication date: September 28, 2023Inventors: Jose LEPE, Joseph T. GREENSPUN, Giana MONTERO GARNIER, Michel M. MAHARBIZ, Jose M. CARMENA, Kunitake ABE, Hiroshi ANDO, Chisato KAMEOKA, Yuki OKUDA, Toshiyuki FUNATSU, Shuhei FUJITA
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Patent number: 7374923Abstract: A screening tool and a screening method for a therapeutic agent for type II diabetes, particularly an agent for alleviating insulin resistance are disclosed. A novel polypeptide, a polynucleotide, a vector, a promoter, and a transformant which are useful in the screening tool and the screening method, are also disclosed.Type: GrantFiled: November 7, 2006Date of Patent: May 20, 2008Assignee: Astellas Pharma Inc.Inventors: Kunitake Abe, Masayoshi Takeda, Noboru Yamaji, Miyuki Katou, Tetsuo Matsui
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Publication number: 20080102459Abstract: The present invention relates to a method of screening for an antiobesity agent, an antidiabetic agent, and/or a hypolipidemic agent, comprising the step of analyzing whether or not a substance to be tested promotes an expression and/or a function of an angiopoietin-related growth factor. The present invention relates to a method of screening for an agent for promoting an expression and/or a function of an angiopoietin-related growth factor.Type: ApplicationFiled: December 1, 2005Publication date: May 1, 2008Applicants: ASTELLAS PHARMA INC., KEIO UNIVERSITYInventors: Kunio Yasunaga, Noboru Yamaji, Kunitake Abe, Yuichi Oike
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Publication number: 20070077591Abstract: A screening tool and a screening method for a therapeutic agent for type II diabetes, particularly an agent for alleviating insulin resistance are disclosed. A novel polypeptide, a polynucleotide, a vector, a promoter, and a transformant which are useful in the screening tool and the screening method, are also disclosed.Type: ApplicationFiled: November 7, 2006Publication date: April 5, 2007Inventors: Kunitake Abe, Masayoshi Takeda, Noboru Yamaji, Miyuki Katou, Tetsuo Matsui
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Patent number: 7193073Abstract: A novel polypeptide, a polynucleotide encoding this polypeptide, an expression vector comprising this polynucleotide, a cell transfected with the expression vector, an antibody binding to the above polypeptide, a convenient screening method for obtaining an agent for treating joint diseases, and a process for manufacturing a pharmaceutical composition for treating joint diseases are disclosed. The polypeptide is a novel aggrecanase causative of joint diseases (particularly an OA disease).Type: GrantFiled: November 23, 2005Date of Patent: March 20, 2007Assignee: Astellas Pharma Inc.Inventors: Noboru Yamaji, Kouichi Nishimura, Kunitake Abe
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Patent number: 7157567Abstract: A screening tool and a screening method for a therapeutic agent for type II diabetes, particularly an agent for alleviating insulin resistance are disclosed. A novel polypeptide, a polynucleotide, a vector, a promoter, and a transformant which are useful in the screening tool and the screening method, are also disclosed.Type: GrantFiled: February 19, 2003Date of Patent: January 2, 2007Assignee: Astellas Pharma, Inc.Inventors: Kunitake Abe, Noboru Yamaji, Miyuki Katou, Tetsuo Matsui
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Patent number: 7094590Abstract: A novel polypeptide, a polynucleotide encoding this polypeptide, an expression vector comprising this polynucleotide, a cell transfected with the expression vector, an antibody binding to the above polypeptide, a convenient screening method for obtaining an agent for treating joint diseases, and a process for manufacturing a pharmaceutical composition for treating joint diseases are disclosed. The polypeptide is a novel aggrecanase causative of joint diseases (particularly an OA disease).Type: GrantFiled: December 17, 2001Date of Patent: August 22, 2006Assignee: Astellas Pharma Inc.Inventors: Noboru Yamajii, Kouichi Nishimura, Kunitake Abe
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Publication number: 20060078957Abstract: A novel polypeptide, a polynucleotide encoding this polypeptide, an expression vector comprising this polynucleotide, a cell transfected with the expression vector, an antibody binding to the above polypeptide, a convenient screening method for obtaining an agent for treating joint diseases, and a process for manufacturing a pharmaceutical composition for treating joint diseases are disclosed. The polypeptide is a novel aggrecanase causative of joint diseases (particularly an OA disease).Type: ApplicationFiled: November 23, 2005Publication date: April 13, 2006Inventors: Noboru Yamajii, Kouichi Nishimura, Kunitake Abe
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Publication number: 20060014931Abstract: Disclosing a promoter of the protease MDTS9, which is induced by TGF-?, which is involved in the metabolism of extracellular matrix, and in which the expression of the gene thereof is elevated in renal failure model animals, which promoter is useful as a tool for screening an agent for treating and/or preventing chronic renal failure, as well as a method for screening an agent for treating and/or preventing chronic renal failure by selecting an inhibitor of the promoter.Type: ApplicationFiled: June 19, 2003Publication date: January 19, 2006Inventors: Masayoshi Takeda, Kunitake Abe, Noboru Yamaji
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Publication number: 20040241778Abstract: A screening tool and a screening method for a therapeutic agent for type II diabetes, particularly an agent for alleviating insulin resistance are disclosed. A novel polypeptide, a polynucleotide, a vector, a promoter, and a transformant which are useful in the screening tool and the screening method, are also disclosed.Type: ApplicationFiled: March 31, 2004Publication date: December 2, 2004Inventors: Kunitake Abe, Masayoshi Takeda, Noboru Yamaji, Miyuki Katou, Tetsuo Matsui
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Publication number: 20040142445Abstract: This invention provides a novel metalloprotease having an aggrecanase activity which causes joint diseases, a gene coding for this metalloprotease, a promoter of the above metalloprotease, a method for screening a drug with the use of the above metalloprotease and a pharmaceutical composition for inhibiting degradation of proteoglycans, which comprises as the active ingredient a substance capable of inhibiting the aggrecanase activity of the above metalloprotease.Type: ApplicationFiled: January 26, 2004Publication date: July 22, 2004Applicants: YAMANOUCHI PHARMACEUTICAL CO., LTD., KAZUSA DNA RESEARCH INSTITUTEInventors: Noboru Yamaji, Kouichi Nishimura, Kunitake Abe, Osamu Ohara, Takahiro Nagase, Nobuo Nomura
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Patent number: 6716613Abstract: This invention provides a novel metalloprotease having an aggrecanase activity which causes joint diseases, a gene coding for this metalloprotease, a promoter of the above metalloprotease, a method for screening a drug with the use of the above metalloprotease and a pharmaceutical composition for inhibiting degradation of proteoglycans, which comprises as the active ingredient a substance capable of inhibiting the aggrecanase activity of the above metalloprotease.Type: GrantFiled: December 10, 2001Date of Patent: April 6, 2004Assignees: Yamanouchi Pharmaceutical Co., Ltd., Kazusa DNA Research InstituteInventors: Noboru Yamaji, Kouichi Nishimura, Kunitake Abe, Osamu Ohara, Takahiro Nagase, Nobuo Nomura
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Publication number: 20030185828Abstract: A novel polypeptide, a polynucleotide encoding this polypeptide, an expression vector comprising this polynucleotide, a cell transfected with the expression vector, an antibody binding to the above polypeptide, a convenient screening method for obtaining an agent for treating joint diseases, and a process for manufacturing a pharmaceutical composition for treating joint diseases are disclosed.Type: ApplicationFiled: October 2, 2002Publication date: October 2, 2003Inventors: Noboru Yamaji, Kouichi Nishimura, Kunitake Abe
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Publication number: 20030129658Abstract: A novel polypeptide, a polynucleotide encoding the polypeptide, an expression vector comprising the polynucleotide, a cell transfected with the expression vector, an antibody or a fragment thereof binding to the polypeptide, and a process for producing the polypeptide are disclosed.Type: ApplicationFiled: November 26, 2002Publication date: July 10, 2003Inventors: Noboru Yamaji, Kouichi Nishimura, Kunitake Abe, Makoto Ogino
