Patents by Inventor Kunzang CHOSDOL

Kunzang CHOSDOL has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Placental like alkaline phosphatase (PLAP) promoter mediated cell targeting
    Patent number: 9868960
    Abstract: The present invention relates to cell specific therapeutic modality by using a region of the PLAP Promoter. The invention further relates to specific expression of therapeutically PLAP useful sequences for specific transcriptional activation of this gene. The invention also relates to the PLAP region which may be used alone or in combination with other regions like enhancer sequences that augment cell or tumour specific gene expression.
    Type: Grant
    Filed: May 10, 2014
    Date of Patent: January 16, 2018
    Assignees: National Brain Research Centre, All India Institute of Medical Sciences
    Inventors: Subrata Sinha, Imran Khan, Mohammad Khalid Zakaria, Kunzang Chosdol, Parthaprasad Chattopadhyay
  • gene in cancer and inflammation
    Patent number: 9556437
    Abstract: The present invention demonstrates for the first time that FAT1 plays an important role in modulating PDCD4 expression, which in turn regulates AP-1 dependent transcription, controls processes crucial for migration and invasion in cancer cells, controls induction of a pro-inflammatory micro environment in cancer cells. The study illustrates a link between inflammation and cancer in cells or in a subject. This work highlights the importance of FAT1 in the induction of the cellular pathways of migration and invasion, proteolysis of the ECM and the expression of pro-inflammatory molecules leading to a favorable micro environment for tumor and cancer progression.
    Type: Grant
    Filed: July 3, 2014
    Date of Patent: January 31, 2017
    Assignees: DEPARTMENT OF BIOTECHNOLOGY (DBT), ALL INDIA INSTITUTE OF MEDIAL SCIENCES (AIIMS), NATIONAL BRAIN RESEARCH CENTRE (NBRC)
    Inventors: Kunzang Chosdol, Bhawana Dikshit, Subrata Sinha
  • Placental Like Alkaline Phosphatase (PLAP) Promoter Mediated Cell Targeting
    Publication number: 20160053279
    Abstract: The present invention relates to cell specific therapeutic modality by using a region of the PLAP Promoter. The invention further relates to specific expression of therapeutically PLAP useful sequences for specific transcriptional activation of this gene. The invention also relates to the PLAP region which may be used alone or in combination with other regions like enhancer sequences that augment cell or tumour specific gene expression.
    Type: Application
    Filed: May 10, 2014
    Publication date: February 25, 2016
    Inventors: Subrata SINHA, Imran KHAN, Mohammad Khalid ZAKARIA, Kunzang CHOSDOL, Parthaprasad CHATTOPADHYAY
  • FAT1 GENE IN CANCER AND INFLAMMATION
    Publication number: 20140323547
    Abstract: The present invention demonstrates for the first time that FAT1 plays an important role in modulating PDCD4 expression, which in turn regulates AP-1 dependent transcription, controls processes crucial for migration and invasion in cancer cells, controls induction of a pro-inflammatory micro environment in cancer cells. The study illustrates a link between inflammation and cancer in cells or in a subject. This work highlights the importance of FAT1 in the induction of the cellular pathways of migration and invasion, proteolysis of the ECM and the expression of pro-inflammatory molecules leading to a favorable micro environment for tumor and cancer progression.
    Type: Application
    Filed: July 3, 2014
    Publication date: October 30, 2014
    Inventors: Kunzang CHOSDOL, Bhawana DIKSHIT, Subrata SINHA