Patents by Inventor Kuo-Chen Chou

Kuo-Chen Chou has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Modified BACE
    Patent number: 7273743
    Abstract: The present invention relates to recombinant human BACE polypeptides. More particularly, the invention relates to recombinant human BACE polypeptides that have a modified amino acid sequence at position 33 of the BACE sequence, as well as to polynucleotides, expression vectors, host cells, and methods for producing the modified recombinant human BACE polypeptides.
    Type: Grant
    Filed: February 21, 2003
    Date of Patent: September 25, 2007
    Assignee: Elan Pharmaceuticals, Inc.
    Inventors: Kuo-Chen Chou, W. Jeffrey Howe
  • Modified BACE
    Patent number: 7244606
    Abstract: The present invention relates to recombinant human BACE polypeptides. More particularly, the invention relates to recombinant human BACE polypeptides that have a modified amino acid sequence at position 33 of the BACE sequence, as well as to polynucleotides, expression vectors, host cells, and methods for producing the modified recombinant human BACE polypeptides.
    Type: Grant
    Filed: October 31, 2005
    Date of Patent: July 17, 2007
    Assignee: Elan Pharmaceuticals, Inc.
    Inventors: Kuo-Chen Chou, W. Jeffrey Howe
  • Modified BACE
    Publication number: 20060094103
    Abstract: The present invention relates to recombinant human BACE polypeptides. More particularly, the invention relates to recombinant human BACE polypeptides that have a modified amino acid sequence at position 33 of the BACE sequence, as well as to polynucleotides, expression vectors, host cells, and methods for producing the modified recombinant human BACE polypeptides.
    Type: Application
    Filed: October 31, 2005
    Publication date: May 4, 2006
    Inventors: Kuo-Chen Chou, W. Howe
  • Modified BACE
    Publication number: 20040005691
    Abstract: The present invention relates to recombinant human BACE polypeptides. More particularly, the invention relates to recombinant human BACE polypeptides that have a modified amino acid sequence at position 33 of the BACE sequence, as well as to polynucleotides, expression vectors, host cells, and methods for producing the modified recombinant human BACE polypeptides.
    Type: Application
    Filed: February 21, 2003
    Publication date: January 8, 2004
    Inventors: Kuo-Chen Chou, W. Jeffrey Howe
  • Method and apparatus for predicting a signal peptide cleavage site
    Publication number: 20020019012
    Abstract: A method and apparatus for predicting a signal peptide cleavage site associated with an amino acid sequence is provided. The system determines a size (X+Y) for a scanning window based on a positive training data set and a negative training data set. The scanning window has a signal peptide portion of length X and a mature protein portion of length Y. The training data set is indicative of a plurality of amino acid sequences with known peptide cleavage sites. The method then scans the window across the amino acids from an amino acid sequence suspected of containing a signal peptide looking for the most likely cleavage site based on the training data.
    Type: Application
    Filed: April 19, 2001
    Publication date: February 14, 2002
    Inventor: Kuo-Chen Chou