Abstract: The present invention provides Wnt pathway agonists and related compositions, which may be used in any of a variety of therapeutic methods for the treatment of diseases.

Abstract: The present invention relates to a transgenic plant overexpressing an antioxidant protein 1 (ATX1)-like polypeptide, which exhibits resistance to excess or deficiency of copper. The present invention also relates to a method of phytoremediation of an environment contaminated with copper by growing a transgenic plant overexpressing an ATX1-like polypeptide in the environment.

Abstract: Disclosed herein are recombinant copper or zinc binding polypeptides containing at least one copper or zinc binding motif and a sequence heterologous to it. Also disclosed is a method to reduce the concentration of a free copper or zinc ion in a substrate by contacting it with a recombinant polypeptide containing a copper or zinc binding motif. A further method relates to reducing the concentration of a free copper or zinc ion in a substrate by contacting it with a host cell that expresses a recombinant polypeptide containing a copper or zinc binding motif.

Abstract: Disclosed herein are recombinant copper or zinc binding polypeptides containing at least one copper or zinc binding motif and a sequence heterologous to it. Also disclosed is a method to reduce the concentration of a free copper or zinc ion in a substrate by contacting it with a recombinant polypeptide containing a copper or zinc binding motif. A further method relates to reducing the concentration of a free copper or zinc ion in a substrate by contacting it with a host cell that expresses a recombinant polypeptide containing a copper or zinc binding motif.

Abstract: A denture cream for cleaning dentures and removable dental prostheses comprising a peroxide stabilized against chemical degradation by a combination of a bicarbonate and a phosphate, such as an alkali monofluorophosphate.

Abstract: An oral composition for treatment of hypersensitive teeth in which the salty taste of the desensitizing salt, such as a potassium or strontium salt, is masked by baking soda, sodium bicarbonate.

Abstract: A method for treating dentinal hypersensitivity by administering a therapeutic amount of an alginate to a hypersensitive tooth.

Abstract: Phosphate-free oral compositions containing cationically charged colloids are effective to treat tooth hypersensitivity.

Abstract: A solid dosage form for relieving xerostomia symptoms comprising a lubricating polymer comprising polyethylene oxide and a sialogogue in a pharmaceutically acceptable, substantially non-cariogenic, carrier.

Abstract: Omega-3, 20-22 carbon atom, hexa- or penta-unsaturated fatty acids are used in the treatment of periodontal disease.

Abstract: Synergistic compositions comprising an antioxidant and an arylpropionic, non-steroidal anti-imflammatory drug used to treat certain diseases are disclosed. The compositions inhibit production of arachidonic acid cascade end-products which have been implicated as causes of tissue-destruction in periodontal disease. The compositions are administered in combination with a carrier, which may be a mucosal-tenacious polymer selected from the groups of semi-solid pastes, gels, ointments, liquids or films.

Abstract: A toothpaste having high polishing and cleaning properties suitable for use in the removal of coffee and tea stains comprises about 10-35% of an abrasive system combined with a non-toxic paste, said abrasive system comprising a combination of anhydrous aluminum silicate and diatomaceous silica in a ratio of about 0.5:1-1.5:1, said toothpaste having a radioactive dentin abrasion index not in excess of about 150. The system provides excellent fluoride stability during storage and does not interfere with fluoride bioavailability.

Abstract: An effervescent tablet is produced by preparing a powdered tabletable composition containing stannous fluoride and malic acid and an alkali metal bicarbonate in a weight ratio of about 3:2 as the effervescent couple.