Patents by Inventor Kuo-Hsun CHIU

Kuo-Hsun CHIU has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method for analyzing secretome, biomarker for lung cancer metastasis, and siRNA compound for inhibiting lung cancer metastasis
    Patent number: 8912155
    Abstract: A method for analyzing secretome, a biomarker for lung cancer metastasis, and a siRNA compound for inhibiting lung cancer metastasis are disclosed. The method for analyzing secretome of the present invention comprises the following steps: (A) collecting proteome secreted from a cell; (B) providing a purification gel, wherein the purification gel comprises a low-density layer, and a high-density layer, and the low-density layer is stacked on the high-density layer; (C) adding the proteome on the low-density layer, and separating the proteome through the low-density layer and the high-density layer of the purification gel; (D) collecting the separated proteome on the interface between the low-density layer and high-density layer, and tagging the separated proteome with a reagent after digestion; and (E) analyzing the separated proteome tagged with the reagent, and comparing an analysis result with a proteomic database.
    Type: Grant
    Filed: December 27, 2011
    Date of Patent: December 16, 2014
    Assignee: National Cheng Kung University
    Inventors: Pao-Chi Liao, Ying-Hwa Chang, Kuo-Hsun Chiu, Yu-Shun Wu, Shu-Hui Lee
  • METHOD FOR ANALYZING SECRETOME, BIOMARKER FOR LUNG CANCER METASTASIS, AND SIRNA COMPOUND FOR INHIBITING LUNG CANCER METASTASIS
    Publication number: 20120270254
    Abstract: A method for analyzing secretome, a biomarker for lung cancer metastasis, and a siRNA compound for inhibiting lung cancer metastasis are disclosed. The method for analyzing secretome of the present invention comprises the following steps: (A) collecting proteome secreted from a cell; (B) providing a purification gel, wherein the purification gel comprises a low-density layer, and a high-density layer, and the low-density layer is stacked on the high-density layer; (C) adding the proteome on the low-density layer, and separating the proteome through the low-density layer and the high-density layer of the purification gel; (D) collecting the separated proteome on the interface between the low-density layer and high-density layer, and tagging the separated proteome with a reagent after digestion; and (E) analyzing the separated proteome tagged with the reagent, and comparing an analysis result with a proteomic database.
    Type: Application
    Filed: December 27, 2011
    Publication date: October 25, 2012
    Applicant: NATIONAL CHENG KUNG UNIVERSITY
    Inventors: Pao-Chi LIAO, Ying-Hwa CHANG, Kuo-Hsun CHIU, Yu-Shun WU, Shu-Hui LEE