Patents by Inventor KUO-HSUN SUNG

KUO-HSUN SUNG has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Polysaccharide-grafted polyethylenimine as a gene carrier
    Patent number: 8716399
    Abstract: The present invention discloses a gene carrier and the preparation method thereof. Chondroitin sulfate (CS) is reacted with methacrylic anhydride (MA) to form chrondroitin sulfate-methacrylate (CSMA), which is further covalently bound with polyethylenimine (PEI) via the Michael addition to produce a CSMA-PEI gene carrier. The CSMA-PEI gene carrier can effectively reduce the cytotoxicity of PEI and enhance the transfection efficiency of PEI.
    Type: Grant
    Filed: November 18, 2011
    Date of Patent: May 6, 2014
    Assignee: Kaohsiung Medical University
    Inventors: Li-Fang Wang, Kuo-Hsun Sung, Yu-Lun Lo
  • POLYSACCHARIDE-GRAFTED POLYETHYLENIMINE AS A GENE CARRIER
    Publication number: 20130030119
    Abstract: The present invention discloses a gene carrier and the preparation method thereof. Chondroitin sulfate (CS) is reacted with methacrylic anhydride (MA) to form chrondroitin sulfate-methacrylate (CSMA), which is further covalently bound with polyethylenimine (PEI) via the Michael addition to produce a CSMA-PEI gene carrier. The CSMA-PEI gene carrier can effectively reduce the cytotoxicity of PEI and enhance the transfection efficiency of PEI.
    Type: Application
    Filed: November 18, 2011
    Publication date: January 31, 2013
    Applicant: KAOHSIUNG MEDICAL UNIVERSITY
    Inventors: LI-FANG WANG, KUO-HSUN SUNG, YU-LUN LO