Abstract: The present invention is directed to methods, kits, and uses of inhibitors of LCMV mediated NF-?B activation to treat viral infections and inflammatory conditions.

Abstract: The present invention is directed to methods, kits, and uses of inhibitors of LCMV mediated NF-?B activation to treat viral infections and inflammatory conditions.

Abstract: Toll-like receptor 2 (TLR2) has been found to mediate certain effects of HSV infection, particularly in neonates. Compounds that decrease TLR2 expression or activity are useful for ameliorating such deleterious effects.

Abstract: The present invention is directed to methods, kits, and uses of inhibitors of LCMV mediated NF-?B activation to treat viral infections and inflammatory conditions.

Abstract: The present invention provides methods of identifying candidate therapeutic agents for use in the treatment of acute pancreatitis.

Abstract: The present invention is directed to methods, kits, and uses of inhibitors of LCMV mediated NF-?B activation to treat viral infections and inflammatory conditions.

Abstract: It has been found that Toll-like receptor 1 and Toll-like receptor 2 (TLR2) physically interact. Antibodies that specifically bind to TLR2 and selectively inhibit induction of cytokines are also described. The invention relates to specific antibodies that selectively bind to TLR2, and to methods of identifying compounds that selectively interfere with signaling through TLR1/TLR2 complexes.

Abstract: It has been found that Toll-like receptor 1 and Toll-like receptor 2 (TLR2) physically interact. Antibodies that specifically bind to TLR2 and selectively inhibit induction of cytokines are also described. The invention relates to specific antibodies that selectively bind to TLR2, and to methods of identifying compounds that selectively interfere with signaling through TLR1/TLR2 complexes.

Abstract: It has been found that Toll-like receptor 1 and Toll-like receptor 2 (TLR2) physically interact. Antibodies that specifically bind to TLR2 and selectively inhibit induction of cytokines are also described. The invention relates to specific antibodies that selectively bind to TLR2, and to methods of identifying compounds that selectively interfere with signaling through TLR1/TLR2 complexes.

Abstract: The present invention provides methods of identifying candidate therapeutic agents for use in the treatment of acute pancreatitis.

Abstract: The present invention provides a method of printing which includes providing a substrate having an inked surface. The inked surface is typically achieved using an offset lithographic printing press. A thermoplastic polymer powder is applied to the inked surface. The surface is then fused. An advantage of the prepared substrate is that there is reduced contamination of electrostatographic fusing systems when fused by heat and pressure fixing. Another aspect of the invention further provides a method of fusing a substrate having an inked surface wherein a thermoplastic powder has been applied to the inked surface prior to stacking the uncured offset prints.

Abstract: The invention relates to cleaning deposits from a moving surface within a printer. According to just one aspect of the invention a cleaning device for cleaning a moving surface in a printer is provided. The cleaning device includes a blade defining at least one cleaning edge configured to engage the moving surface in the printer, the blade including a multitude of blade segments spaced along a width thereof.

Abstract: The invention relates to cleaning deposits from rollers in a fusing apparatus for a printer. Cleaning devices and processes for cleaning a moving surface in a printer are provided. According to just one aspect of the invention, a common mount is provided. A first cleaning blade defines a first edge configured to engage the moving surface in the printer and has a first marginal end opposite the first edge. A second cleaning blade defines a second edge configured to engage the moving surface in the printer and has a second marginal end opposite the second edge. The first marginal end and the second marginal end are held by the common mount.

Abstract: A process for the manufacture of iodopropynyl butylcarbamate (IPBC) is disclosed wherein the subject reaction is carried out in an aqueous solution of a suitable surfactant. The iodination reactant is metallic iodide salt which serves as a donor of I+ ions. The I+ ion is generated on an as needed basis, during the reaction sequence, hence the formation of undesirable isomers of IPBC are minimized. The process of this invention produces a highly purified IPBC having, preferably, a low moisture content (wet-cake). The IPBC produced by such a process is also disclosed herein.

Abstract: A method of printing comprising the steps of marking the surface of a test preprinted media with a first marking material; placing the media adjacent to a transfer media; disposing the test media and the transfer media into the nip of a fuser roller assembly to thereby apply predetermined heat and pressure thereto; removing the test media and the transfer media from the nip of the fuser roller after a predetermined time; and, measuring the density of the first marking material which has been offset to the transfer media.

Abstract: The present invention provides for the use of G protein binding agents for prophylactic and/or therapeutic treatments of septic shock. The present invention provides methods of using agents which bind G protein to treat a subject having or susceptible to septic shock. The present invention further pertains to compositions for treating a subject for septic shock. The composition includes an effective amount of a G protein binding agent and, optionally, an antibiotic and a pharmaceutically acceptable carrier. Other aspects of the invention include packaged agents which bind G proteins for treating septic shock.

Abstract: Toll-like receptor 2 (TLR2) has been found to mediate certain effects of HSV infection, particularly in neonates. Compounds that decrease TLR2 expression or activity are useful for ameliorating such deleterious effects.

Abstract: The fuser roller and heater rollers of the fusing system can become contaminated with ink and other foreign material when pre-printed materials are run through them. The contamination can create regions of cold spots, which in turn results in poor fusing. Other image defects may result. According the various aspects of the invention, a heater roller cleaner, method and apparatus are provided for applying an array of differential pressure generating areas to a heater roller surface in a fuser assembly while rotating the heater roller surface.

Abstract: It has been found that Toll-like receptor 1 and Toll-like receptor 2 (TLR2) physically interact. Antibodies that specifically bind to TLR2 and selectively inhibit induction of cytokines are also described. The invention relates to specific antibodies that selectively bind to TLR2, and to methods of identifying compounds that selectively interfere with signaling through TLR1/TLR2 complexes.

Abstract: A process for the manufacture of iodopropynyl butylcarbamate (IPBC) is disclosed wherein the subject reaction is carried out in an aqueous solution of a suitable surfactant. The iodination reactant is metallic iodide salt which serves as a donor of I+ ions. The I+ ion is generated on an as needed basis, during the reaction sequence, hence the formation of undesirable isomers of IPBC are minimized. The process of this invention produces a highly purified IPBC having, preferably, a low moisture content (wet-cake). The IPBC produced by such a process is also disclosed herein.