Patents by Inventor Kurt Brillhart

Kurt Brillhart has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Labeled complementary oligonucleotides to detect oligonucleotide-linked ligands
    Patent number: 7494776
    Abstract: Methods for determining the presence of an analyte in a sample are disclosed, in which a capture agent is bound to the analyte at a first epitope and a detection agent is bound at a second epitope, and in which the detection agent includes an oligonucleotide to which a labeled, complementary oligonucleotide can be hybridized.
    Type: Grant
    Filed: July 7, 2005
    Date of Patent: February 24, 2009
    Assignee: Beckman Coulter, Inc.
    Inventors: Robert Bruce Wallace, M. Parameswara Reddy, Kurt Brillhart
  • Labeled complimentary oligonucleotides to detect oligonucleotide-linked ligands
    Publication number: 20070009914
    Abstract: Methods for determining the presence of an analyte in a sample are disclosed, in which a capture agent is bound to the analyte at a first epitope and a detection agent is bound at a second epitope, and in which the detection agent includes an oligonucleotide to which a labeled, complementary oligonucleotide can be hybridized.
    Type: Application
    Filed: July 7, 2005
    Publication date: January 11, 2007
    Inventors: Robert Wallace, M. Reddy, Kurt Brillhart
  • Cell-based microarrays, and methods for their preparation and use
    Publication number: 20060292559
    Abstract: The present invention is in the field of chemistry and biotechnology. The present invention relates to cell-based microarrays, improved methods for forming such arrays, and methods for using such arrays in diagnostics, therapeutics and research. The invention particularly concerns microarrays in which ligands of a target cells are immobilized to the array support via ligand-binding molecules bound to an oligonucleotide that is hybridized to a support-immobilized oligonucleotide.
    Type: Application
    Filed: June 7, 2006
    Publication date: December 28, 2006
    Applicant: Beckman Coulter, Inc.
    Inventors: M. Reddy, Kurt Brillhart, Daniel Keys
  • Reducing microarray variation with internal reference spots
    Publication number: 20040229226
    Abstract: The present invention provides a system using internal reference spots to reduce microarray assay variation. A microarray device for quantifying a plurality of target ligands in a sample includes a solid support having a plurality of test areas; a plurality of different target capture ligands immobilized onto the test areas; and at least one reference capture ligand immobilized onto the test areas. The reference capture ligand captures a reference ligand not normally present in the sample.
    Type: Application
    Filed: May 16, 2003
    Publication date: November 18, 2004
    Inventors: M. Parameswara Reddy, Kurt Brillhart, Firdous Farooqui, Daniel Keys