Patents by Inventor Kurt-Jürgen Hoffmann

Kurt-Jürgen Hoffmann has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Oxabispidine compounds useful in the treatment of cardiac arrhythmias
    Patent number: 7772229
    Abstract: There is provided compounds of formula I, wherein R1, R2, R3, R4, R41 to R46, A, B and G have meanings given in the description, which are useful in the prophylaxis and in the treatment of arrhythmias, in particular atrial and ventricular arrhythmias.
    Type: Grant
    Filed: March 22, 2006
    Date of Patent: August 10, 2010
    Assignee: AstraZeneca AB
    Inventors: Annika Björe, Magnus Björsne, Kurt-Jürgen Hoffmann, Fritiof Pontėn, Gert Strandlund, Peder Svensson, Michael Wilsterman
  • Prodrugs of thrombin inhibitors
    Patent number: 7354905
    Abstract: There is provided compounds of formula I, R1O(O)C—CH2—(R)Cgl-Aze-Pab-R2I wherein R1 and R2 have meanings given in the description, which are useful as prodrugs of inhibitors of trypsin-like proteases, such as thrombin, and in particular in the treatment of conditions where inhibition of thrombin is required (eg thrombosis) or as anticoagulants.
    Type: Grant
    Filed: February 12, 2004
    Date of Patent: April 8, 2008
    Assignee: AstraZeneca AB
    Inventors: Thomas Antonsson, David Gustafsson, Kurt-Jürgen Hoffmann, Jan-Erik Nyström, Henrik Sörensen, Mikael Sellén
  • Oxabispidine compounds useful in the treatment of cardiac arrhythmias
    Patent number: 7351821
    Abstract: There is provided compounds of formula I, wherein R1, R2, R3, R4, R41 to R46, A, B and G have meanings given in the description, which are useful in the prophylaxis and in the treatment of arrhythmias, in particular atrial and ventricular arrhythmias.
    Type: Grant
    Filed: December 18, 2006
    Date of Patent: April 1, 2008
    Assignee: AstraZeneca AB
    Inventors: Annika Björe, Magnus Björsne, David Cladingboel, Kurt-Jürgen Hoffmann, John Pavey, Fritiof Pontén, Gert Strandlund, Peder Svensson, Colin Thomson, Michael Wilsterman
  • 3,8-Diazabicyclo[3.2.1]octanes and their use in the treatment of cardiac arrhythmias
    Patent number: 7012074
    Abstract: There is provided compounds of formula (I), wherein R1, R2 and Ra to Rb have meanings given in the description, which are useful in the prophylaxis and in the treatment of arrhythmias, in particular atrial and ventricular arrhythmias.
    Type: Grant
    Filed: October 18, 2001
    Date of Patent: March 14, 2006
    Assignee: AstraZeneca AB
    Inventors: Magnus Bjorsne, Kurt-Jürgen Hoffmann, Fritiof Pontén, Gert Strandlund, Peder Svensson, Michael Wilstermann
  • Bispidine compounds useful in the treatment of cardiac arrythmias
    Patent number: 6887881
    Abstract: There is provided compounds of formula I, wherein R1, R2, R3, R4, R5a, R5b, R6, X, A, B and D have meanings given in the description, which are useful in the prophylaxis and in the treatment of arrhythmias, in particular atrial and ventricular arrhythmias.
    Type: Grant
    Filed: June 15, 2000
    Date of Patent: May 3, 2005
    Assignee: AstraZeneca AB
    Inventors: Annika Björ, Magnus Björsne, Torbjörn Halvarsson, Kurt-Jürgen Hoffmann, Bertil Samuelsson, Gert Strandlund
  • Oxabispidine compounds useful in the treatment of cardiac arrhyythmias
    Patent number: 6559143
    Abstract: There is provided compounds of formula I, wherein R1, R2, R3, R4, R41 to R46, A, B and G have meanings given in the description, which are useful in the prophylaxis and in the treatment of arrhythmias, in particular atrial and ventricular arrhythmias.
    Type: Grant
    Filed: October 16, 2000
    Date of Patent: May 6, 2003
    Assignee: AstraZeneca AB
    Inventors: Annika Björe, Magnus Björsne, Kurt-Jürgen Hoffmann, Fritiof Pontén, Gert Strandlund, Peder Svensson, Michael Wilsterman
  • Bispidine compounds useful in the treatment of cardiac arrythmias
    Patent number: 6465481
    Abstract: There is provided compounds of formula I, wherein R1, R2, R3, R4, R5a, R5b, R6, R9, X, A and B have meanings given in the description, which are useful in the prophylaxis and in the treatment of arrhythmias, in particular atrial and ventricular arrhythmias.
    Type: Grant
    Filed: September 7, 2000
    Date of Patent: October 15, 2002
    Assignee: AstraZeneca AB
    Inventors: Marianne Frantsi, Kurt-Jürgen Hoffmann, Gert Strandlund
  • Bispidine antiarrhythmic compounds
    Patent number: 6291475
    Abstract: There is provided a compound of formula I, wherein R1, R2, R9, R10, R11, R12, X, A and B have meanings given in the description, which are useful in the prophylaxis and in the treatment of arrhythmias, in particular atrial and ventricular arrhythmias.
    Type: Grant
    Filed: January 12, 1999
    Date of Patent: September 18, 2001
    Assignee: AstraZeneca AB
    Inventors: Christer Alstermark, Annika Björe, Magnus Björsne, Marianne Frantsi, Torbjörn Halvarsson, Kurt-Jürgen Hoffmann, Eva-Lotte Lindstedt, Magnus Polla, Gert Strandlund
  • Prodrugs of thrombin inhibitors
    Patent number: 6262028
    Abstract: There is provided compounds of formula I, R1O(O)C—CH2—(R)Cgl—Aze—Pab—R  I wherein R1 and R2 have meanings given in the description, which are useful as prodrugs of inhibitors of trypsin-like proteases, such as thrombin, and in particular in the treatment of conditions where inhibition of thrombin is required (eg thrombosis) or as anticoagulants.
    Type: Grant
    Filed: July 15, 1999
    Date of Patent: July 17, 2001
    Assignee: AstraZeneca AB
    Inventors: Thomas Antonsson, David Gustafsson, Kurt-Jürgen Hoffmann, Jan-Erik Nyström, Henrik Sörensen, Mikael Sellén