Patents by Inventor Kurt Pingel

Kurt Pingel has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Thrombin-activated tissue plasminogen activators
    Patent number: 5200340
    Abstract: Zymogens of proteins having fibrinolytic activity are disclosed. The proteins are cleavable by thrombin, the cleavage resulting in the stimulation of fibrinolytic activity. Suitable proteins which may be modified in accordance with the present invention include tissue plasminogen activator, urokinase, and plasminogen variants. The modified molecules are substantially clot-specific, in view of the large amounts of thrombin associated with clots in vivo.
    Type: Grant
    Filed: May 22, 1987
    Date of Patent: April 6, 1993
    Assignee: ZymoGenetics, Inc.
    Inventors: Donald C. Foster, Eileen R. Mulvihill, Patrick J. O'Hara, Kurt Pingel, Shinji Yoshitake