Patents by Inventor Kurt Radscheit

Kurt Radscheit has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Process for the low-racemization preparation of peptide intermediates of the synthesis of gonadorelin and gonadorelin analogs, and new intermediates for this process
    Patent number: 4691008
    Abstract: The invention relates to a process for the preparation of peptides of the formula IU--A.sup.1 --A.sup.2 13 A.sup.3 --A.sup.4 --A.sup.5 --X (I)in whichU denotes a urethane protective group,A.sup.1 denotes Trp or D-Trp,A.sup.2 denotes Ser, Ala or Thr,A.sup.3 denotes Tyr or Phe,A.sup.4 denotes Gly, the residue of a D-amino acid or the residue of a D-amino acid derivative,A.sup.5 denotes Leu, N-methyl-Leu, N-ethyl-Leu, Ser(Bu.sup.t), Cys(But), Asp(OBu.sup.t), Glu(OBu.sup.t), Orn(Boc) or Lys(Boc) andX denotes OBu.sup.t or A.sup.6 --Pro--Y,whereA.sup.6 represents Arg, Orn, Lys or homoarginine, andY represents Gly--NH.sub.2, NH--NH--CO--NH.sub.2, (C.sub.1 -C.sub.3)-alkylamino, cyclopropylamino, (C.sub.1 -C.sub.3)-alkylamino which is substituted with hydroxyl or fluorine, or cycloalkylamino which is substituted with hydroxyl or fluorine, using tripeptides of the formula II,U--A.sup.1 --A.sup.2 --A.sup.3 --OH,in which the residues are defined as above.
    Type: Grant
    Filed: March 25, 1985
    Date of Patent: September 1, 1987
    Assignee: Hoechst Aktiengesellschaft
    Inventors: Rainer Uhmann, Kurt Radscheit
  • Heart glycosides and process for preparing them
    Patent number: 4003997
    Abstract: Cyclic 2',3'-ethers of 3-hydroxy-14,15.beta.-oxido-14.beta.-bufa-4,20,22-trienolide, 3.beta.-(.alpha.-L-rhamnopyranoside) and process for preparing them. The compounds have a strongly positive inotropic activity and may be used in the therapy of cardiac insufficiency.
    Type: Grant
    Filed: August 12, 1974
    Date of Patent: January 18, 1977
    Assignee: Hoechst Aktiengesellschaft
    Inventors: Ulrich Stache, Kurt Radscheit, Werner Fritsch, Werner Haede, Ernst Lindner