Abstract: The invention provides a novel method for producing phenylglycyl chloride hydrochlorides involving reaction of N-substituted phenylglycines with for example thionyl chloride and then gaseous hydrogen chloride, as well as certain novel starting materials for use in this process and certain end-products thereby produced.

Abstract: A pleuromutilin derivative which is 14-desoxy-14-thiocyanatoacetoxy-mutilin is useful as an animal feed additive to increase meat production and also finds application in veterinary medicine as an antibiotic.

Abstract: The present invention concerns novel pleuromutilin derivatives of the formula: ##SPC1##Wherein X, Y and Z are as defined in any one of the following groups:I. X is --CO--CH.sub.2 --R.sub.1 wherein R.sub.1 is hydrogen, chlorine, bromine, iodine, thiocyanato, azido, dithiocarbonic acid-O-alkyl(C.sub.1 to C.sub.5), (N,N-tetramethylene-thiocarbamoyl)-mercapto, --S-phenyl, --S-phenyl substituted by carboxyl or by one or two hydroxyl radicals, --S--pyridyl, --S--alkyl(C.sub.1 to C.sub.5), or --S--alkyl(C.sub.1 to C.sub.5) substituted by one or more amino hydroxyl or carboxyl radicals, Y is vinyl, and Z is hydrogen,Ii. X is --CO--CO--OH, Y is vinyl, and Z is hydrogen,Iii. X is --CO--CH.sub.3, Y is vinyl, and Z and hydrogen,Iv. X is --CO--CH.sub.2 --NH.sub.2, Y is ethyl, and Z is hydrogen,V. X is ##EQU1## Y is ethyl, and Z is hydrogen, VI. X is hydrogen, Y is vinyl, and Z is acetyl, orVii. X is --COR.sub.2, wherein R.sub.2 is alkyl of 1 to 5 carbon atoms, Y is vinyl, and Z is hydrogen.