Abstract: A method of preparing polymeric particles with photographic couplers, such polymeric particles being useful in a microarray, the method comprising the steps of: (a) preparing an organic composition by combining a photographic coupler and a high boiling organic solvent; (b) preparing a separate aqueous composition comprising polymeric particles with functionally active groups on their surfaces; (c) combining the organic composition of step (a) with the aqueous composition of step (b), thereby effecting a loading of said photographic coupler and high boiling organic solvent into said polymeric particles; and (d) attaching biological probes to the functionally active groups on the surfaces of the loaded polymeric particles of step c). Polymeric particles made by the method is also disclosed.

Abstract: The subject matter of the invention is a process for bending a component, e.g. a metal sheet (1) by means of a mechanical force with selective heating by means of a laser beam (6). From one laser beam (6) or several laser beams (6) a radiation field (7, 21) is shaped to form a linear heating zone (9) and at all points along a bend line (8) acts upon the component.