Abstract: An occluding device for occlusion of fluid flow through a lumen of a body vessel is manufactured by wedging fibers between adjacent coil windings of a primary coil so that the fibers extend generally radially across the primary coil body between the primary coil windings and outward therefrom. An elongated adhesive applicator is inserted into the primary coil lumen and subsequently proximally withdrawn while simultaneously depositing along the primary coil windings. The fibers and the adhesive are placed in overlapping locations so that the fibers extend through the adhesive. The fibers are thus blocked from slipping along their length relative to the coil body by the adhesive adhering to the fibers inside the primary coil lumen. The adhesive extends radially outward from the coil lumen no farther than the outer primary coil radius. The adhesive adheres to the fibers and may or may not adhere with the primary coil windings.

Abstract: A clot retrieval system for removing clots from a body lumen. The clot retrieval system includes an elongated sheath and a wire assembly. The wire assembly is comprised of four wire segments, each biased to have a distally extending circumferential curve. Two wire segments are connected together at a proximal end and a distal end to form a first loop, and are connected to a shaft. Two other wire segments are connected together at a proximal end and a distal end to form a second loop and are connected to the first two wire segments. The second loop is covered with a membrane to catch clots. The wire assembly may be compacted by retracting it within the elongated sheath, or expanded by extending it from the elongated sheath.

Abstract: An occluding device for occlusion of fluid flow through a lumen of a body vessel is manufactured by wedging fibers between adjacent coil windings of a primary coil so that the fibers extend generally radially across the primary coil body between the primary coil windings and outward therefrom. An elongated adhesive applicator is inserted into the primary coil lumen and subsequently proximally withdrawn while simultaneously depositing along the primary coil windings. The fibers and the adhesive are placed in overlapping locations so that the fibers extend through the adhesive. The fibers are thus blocked from slipping along their length relative to the coil body by the adhesive adhering to the fibers inside the primary coil lumen. The adhesive extends radially outward from the coil lumen no farther than the outer primary coil radius. The adhesive adheres to the fibers and may or may not adhere with the primary coil windings.

Abstract: An occluding device for occlusion of fluid flow through a lumen of a body vessel manufactured by wedging fibers between adjacent coil windings of a primary coil so that the fibers extend generally radially across the primary coil body between the primary coil windings and outward therefrom. An elongated adhesive is inserted applicator into the primary coil lumen and subsequently proximally withdrawn while simultaneously depositing along the primary coil windings. The fibers and the adhesive are placed in overlapping locations so that the fibers extend through the adhesive. The fibers are thus blocked from slipping along their length relative to the coil body by the adhesive adhering to the fibers inside the primary coil lumen. The adhesive extends radially outward from the coil lumen no farther than the outer primary coil radius. The adhesive adheres to the fibers and may or may not adhere with the primary coil windings.

Abstract: A lumen re-entry system includes a helically wound coil having open proximal and distal ends, and defining a longitudinal movement axis. The helically wound coil includes a distal segment that is relaxed relative to a proximal segment. A tip deflection wire is attached to the relaxed distal segment and coaxially disposed relative to the helically wound coil. Movement of the tip deflection wire moves the lumen re-entry system from an advancement configuration in which the open distal end of the helically wound coil is substantially aligned with the longitudinal movement axis to a deflected configuration. The lumen re-entry system also includes a puncture wire slidably received within the helically wound coil and having a distal puncture tip.

Abstract: A clot removal system includes an elongated tubular sheath and an elongated tubular catheter received within the sheath. A distal segment of the catheter is split into a plurality of catheter wall segments, with each wall segment having a pre-shaped curved configuration. Each wall segment defines at least one scraping edge and has a distal tip that is less stiff than a remaining portion of the wall segment. The clot removal system has a transport configuration in which the distal segment of the catheter is axially aligned with a distal segment of the sheath and the wall segments are urged against the pre-shaped curved configuration by the sheath. The clot removal system also has a deployed configuration in which the distal segment of the catheter is advanced distally beyond the distal segment of the sheath and the wall segments conform to the pre-shaped curved configuration.

Abstract: A clot removal system includes first and second barriers that each have an expanded configuration forming an occlusion within a vessel and a collapsed configuration. At least one deployment device distally deploys the first barrier relative to a clot, and proximally deploys the second barrier relative to the clot. The at least one deployment device also delivers a thrombolytic agent into an isolated segment defined at least in part by the first and second barriers in the expanded configurations, and positions an impeller within the isolated segment. The impeller includes a substantially cylindrical hub having at least two impeller blades attached to rotate with the cylindrical hub. Each of the at least two impeller blades has a proximal end attached to the cylindrical hub and a distal end attached to the cylindrical hub.

Abstract: An occluding device for occlusion of fluid flow through a lumen of a body vessel manufactured by wedging fibers between adjacent coil windings of a primary coil so that the fibers extend generally radially across the primary coil body between the primary coil windings and outward therefrom. An elongated adhesive is inserted applicator into the primary coil lumen and subsequently proximally withdrawn while simultaneously depositing along the primary coil windings. The fibers and the adhesive are placed in overlapping locations so that the fibers extend through the adhesive. The fibers are thus blocked from slipping along their length relative to the coil body by the adhesive adhering to the fibers inside the primary coil lumen. The adhesive extends radially outward from the coil lumen no farther than the outer primary coil radius. The adhesive adheres to the fibers and may or may not adhere with the primary coil windings.

Abstract: An occluding device for occlusion of fluid flow through a lumen of a body vessel manufactured by wedging fibers between adjacent coil windings of a primary coil so that the fibers extend generally radially across the primary coil body between the primary coil windings and outward therefrom. An elongated adhesive is inserted applicator into the primary coil lumen and subsequently proximally withdrawn while simultaneously depositing along the primary coil windings. The fibers and the adhesive are placed in overlapping locations so that the fibers extend through the adhesive. The fibers are thus blocked from slipping along their length relative to the coil body by the adhesive adhering to the fibers inside the primary coil lumen. The adhesive extends radially outward from the coil lumen no farther than the outer primary coil radius. The adhesive adheres to the fibers and may or may not adhere with the primary coil windings.

Abstract: A clot retrieval system for removing clots from a body lumen. The clot retrieval system includes an elongated sheath and a wire assembly. The wire assembly is comprised of four wire segments, each biased to have a distally extending circumferential curve. Two wire segments are connected together at a proximal end and a distal end to form a first loop, and are connected to a shaft. Two other wire segments are connected together at a proximal end and a distal end to form a second loop and are connected to the first two wire segments. The second loop is covered with a membrane to catch clots. The wire assembly may be compacted by retracting it within the elongated sheath, or expanded by extending it from the elongated sheath.

Abstract: A medical device for breaking up and aspirating material, especially intravenous clots, having a catheter, a barrel, and a sheath is disclosed. The catheter has a lumen through which material is aspirated. The barrel has a first and second end connected by a plurality of blades that are self-biased to extend outward. The sheath provides a selective radial constraint such that the blades are constrained when the sheath covers the barrel and unconstrained when the sheath is retracted.

Abstract: An occluding device for occlusion of fluid flow through a lumen of a body vessel manufactured by wedging fibers between adjacent coil windings of a primary coil so that the fibers extend generally radially across the primary coil body between the primary coil windings and outward therefrom. An elongated adhesive is inserted applicator into the primary coil lumen and subsequently proximally withdrawn while simultaneously depositing along the primary coil windings. The fibers and the adhesive are placed in overlapping locations so that the fibers extend through the adhesive. The fibers are thus blocked from slipping along their length relative to the coil body by the adhesive adhering to the fibers inside the primary coil lumen. The adhesive extends radially outward from the coil lumen no farther than the outer primary coil radius. The adhesive adheres to the fibers and may or may not adhere with the primary coil windings.

Abstract: A lumen re-entry system includes a helically wound coil having an open proximal end and an open distal end and defining a longitudinal movement axis. The helically wound coil includes a relaxed distal segment that is relaxed relative to a proximal segment of the coil. A tip deflection wire is attached to the relaxed distal segment and coaxially disposed relative to the helically wound coil. Movement of the tip deflection wire in a proximal direction moves the lumen re-entry system from an advancement configuration in which the open distal end of the helically wound coil is substantially aligned with the longitudinal movement axis to a deflected configuration in which the open distal end of the helically wound coil is deflected relative to the longitudinal movement axis. The lumen re-entry system also includes a puncture wire slidably received within the helically wound coil and having a distal puncture tip.

Abstract: A clot removal system includes an elongated tubular sheath and an elongated tubular catheter received within the sheath. A distal segment of the catheter is split into a plurality of catheter wall segments, with each wall segment having a pre-shaped curved configuration. Each wall segment defines at least one scraping edge and has a distal tip that is less stiff than a remaining portion of the wall segment. The clot removal system has a transport configuration in which the distal segment of the catheter is axially aligned with a distal segment of the sheath and the wall segments are urged against the pre-shaped curved configuration by the sheath. The clot removal system also has a deployed configuration in which the distal segment of the catheter is advanced distally beyond the distal segment of the sheath and the wall segments conform to the pre-shaped curved configuration.

Abstract: A clot removal system includes first and second barriers that each have an expanded configuration forming an occlusion within a vessel and a collapsed configuration. At least one deployment device distally deploys the first barrier relative to a clot, and proximally deploys the second barrier relative to the clot. The at least one deployment device also delivers a thrombolytic agent into an isolated segment defined at least in part by the first and second barriers in the expanded configurations, and positions an impeller within the isolated segment. The impeller includes a substantially cylindrical hub having at least two impeller blades attached to rotate with the cylindrical hub. Each of the at least two impeller blades has a proximal end attached to the cylindrical hub and a distal end attached to the cylindrical hub.

Abstract: A vascular occlusion device is provided having bioremodelable materials for occlusion of vessels. The vascular occlusion device may carry an expandable occlusion bag having an internal cavity filled with a filler member, where at least one of the expandable occlusion bag and the filler member contains bioremodelable material. Use of bioremodelable material may provide stable maintenance of the occlusion device in a vessel site so that its migration into the parent vessel is prevented. In particular, the occlusion device may be absorbed into the body and eventually replaced by the individual's own tissue.

Abstract: A non-implantable valve assembly and a method for controlling flow rates in a medical device are provided. The valve assembly includes a valve member being dimensioned for reception at least partially within a lumen of the medical device. The valve member includes a flow regulator for controlling flow rates in a first direction having a first rate and a second direction having a second rate. The second rate is greater than the first rate.

Abstract: An occluding device for occluding fluid flow through a lumen of a body vessel. The device comprises a coil and fibers attached to the coil. The coil has about 5 to 60 grams of initial tension to facilitate the coil to fold when deployed. The fibers extend from the coil at a length.