Patents by Inventor Kurt Thorn

Kurt Thorn has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • PRIORITIZATION OF GENETIC MODIFICATIONS TO INCREASE THROUGHPUT OF PHENOTYPIC OPTIMIZATION
    Publication number: 20200168291
    Abstract: Systems, methods and computer-readable media are provided for determining modifications to apply to genes within at least one microbial strain to improve phenotypic performance. The disclosure teaches accessing first phenotypic performance data based at least in part upon first gene modifications made to a first set of genes in at least one microbial strain; predicting second phenotypic performance of second gene modifications, based at least in part upon the first phenotypic performance data and at least one modification feature that is common to the first gene modifications and the second gene modifications; and prioritizing the second gene modifications to be applied to a second set of genes based at least in part upon the second phenotypic performance.
    Type: Application
    Filed: June 5, 2018
    Publication date: May 28, 2020
    Applicant: Zymergen Inc.
    Inventors: Anupam Chowdhury, Peter Enyeart, Michael Flashman, Alexander Glennon Shearer, Kurt Thorn
  • Method of affinity purifying proteins using modified bis-arsenical fluorescein
    Publication number: 20050233428
    Abstract: The present invention features methods for purifying polypeptides of interest using a modified Fluorescein arsenical helix binder (FlAsH) compound immobilized on a solid support. An exemplary FlAsH target sequence motif is also presented. Examples of modification of the FlAsH compound which allow immobilization to a solid support are also provided. The present invention also provides DNA constructs for producing a dual affinity tagged polypeptide and methods for purification thereof.
    Type: Application
    Filed: December 14, 2004
    Publication date: October 20, 2005
    Inventors: Ronald Vale, Kurt Thorn, Roger Cooke, Marija Matuska, Nariman Naber
  • Method of affinity purifying proteins using modified bis-arsenical fluorescein
    Patent number: 6831160
    Abstract: The present invention features methods for purifying polypeptides of interest using a modified Fluorescein arsenical helix binder (FlAsH) compound immobilized on a solid support. An exemplary FlAsH target sequence motif is also presented. Examples of modification of the FlAsH compound which allow immobilization to a solid support are also provided. The present invention also provides DNA constructs for producing a dual affinity tagged polypeptide and methods for purification thereof.
    Type: Grant
    Filed: February 11, 2000
    Date of Patent: December 14, 2004
    Assignee: The Regents of the University of California
    Inventors: Ronald D. Vale, Kurt Thorn, Roger Cooke, Marija Matsuka, Nariman Naber