Abstract: The pre-moistened towelette dispenser of the present invention includes a substantially sealed housing to retain moisture within the housing. A roll of pre-moistened, perforated towelettes wound about a cylindrical core is supported within the housing on an axle to allow rotation of the roll of towelettes about the axle to dispense towelettes from the roll. A nipple located in the housing provides a restricted point opening that allows towelettes to exit the housing. The nipple is preferably located in the bottom of the housing to dispense towelettes from the bottom of the housing. An adjustable roll tension system is also provided within the housing. The roll tension system preferably includes a roller that is in contact with and biased against an end cap attached to the cylindrical core at one end of the roll of towelettes. The roll tension system provides resistance to the rotation of the roll of towelettes.