Patents by Inventor Kutlu G. Elpek

Kutlu G. Elpek has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Immunostimulatory compositions and methods
    Patent number: 9079976
    Abstract: The invention provides conjugates comprising an immune co-stimulatory polypeptide and an antigen or infectious agent. The conjugates are useful for generating or enhancing an immune response against the antigen or infectious agent. The invention also provides immune cells modified with a conjugate that are useful for generating or enhancing an immune response to an antigen or infectious agent. The invention also provides immunostimulatory moieties comprising an immune co-stimulatory polypeptide that are useful for stimulating an immune response. The invention also provides immunotherapy methods and methods of treating or preventing infections.
    Type: Grant
    Filed: September 7, 2011
    Date of Patent: July 14, 2015
    Assignee: UNIVERSITY OF LOUISVILLE RESEARCH FOUNDATION, INC.
    Inventors: Haval Shirwan, Kutlu G. Elpek, Esma S. Yolcu
  • IMMUNOSTIMULATORY COMPOSITIONS AND METHODS
    Publication number: 20120171240
    Abstract: The invention provides conjugates comprising an immune co-stimulatory polypeptide and an antigen or infectious agent. The conjugates are useful for generating or enhancing an immune response against the antigen or infectious agent. The invention also provides immune cells modified with a conjugate that are useful for generating or enhancing an immune response to an antigen or infectious agent. The invention also provides immunostimulatory moieties comprising an immune co-stimulatory polypeptide that are useful for stimulating an immune response. The invention also provides immunotherapy methods and methods of treating or preventing infections.
    Type: Application
    Filed: September 7, 2011
    Publication date: July 5, 2012
    Inventors: Haval Shirwan, Kutlu G. Elpek, Esma S. Yolcu
  • Immunostimulatory compositions and methods
    Patent number: 8017582
    Abstract: The invention provides conjugates comprising an immune co-stimulatory polypeptide and an antigen or infectious agent. The conjugates are useful for generating or enhancing an immune response against the antigen or infectious agent. The invention also provides immune cells modified with a conjugate that are useful for generating or enhancing an immune response to an antigen or infectious agent. The invention also provides immunostimulatory moieties comprising an immune co-stimulatory polypeptide that are useful for stimulating an immune response. The invention also provides immunotherapy methods and methods of treating or preventing infections.
    Type: Grant
    Filed: September 3, 2009
    Date of Patent: September 13, 2011
    Assignee: University of Louisville Research Foundation, Inc.
    Inventors: Haval Shirwan, Kutlu G. Elpek, Esma S. Yolcu
  • IN VIVO CELL SURFACE ENGINEERING
    Publication number: 20100240585
    Abstract: The present invention provides methods and compositions for the in vivo engineering of cell surfaces, such as tumor cell surfaces, with one or more immune co-stimulatory polypeptides. The methods, compositions and engineered cells are useful, for example, to stimulate an immune response against the cells. When the engineered cell surfaces are tumor cell surfaces, the methods, compositions and engineered cells are useful for improving a patient's immune response against the cancer and for reducing tumor size and inhibiting tumor growth.
    Type: Application
    Filed: July 8, 2009
    Publication date: September 23, 2010
    Inventors: Haval Shirwan, Kutlu G. Elpek, Esma S. Yolcu
  • IMMUNOSTIMULATORY COMPOSITIONS AND METHODS
    Publication number: 20100158936
    Abstract: The invention provides conjugates comprising an immune co-stimulatory polypeptide and an antigen or infectious agent. The conjugates are useful for generating or enhancing an immune response against the antigen or infectious agent. The invention also provides immune cells modified with a conjugate that are useful for generating or enhancing an immune response to an antigen or infectious agent. The invention also provides immunostimulatory moieties comprising an immune co-stimulatory polypeptide that are useful for stimulating an immune response. The invention also provides immunotherapy methods and methods of treating or preventing infections.
    Type: Application
    Filed: September 3, 2009
    Publication date: June 24, 2010
    Inventors: Haval Shirwan, Kutlu G. Elpek, Esma S. Yolcu
  • Immunostimulatory compositions and methods
    Patent number: 7598345
    Abstract: The invention provides conjugates comprising an immune co-stimulatory polypeptide and an antigen or infectious agent. The conjugates are useful for generating or enhancing an immune response against the antigen or infectious agent. The invention also provides immune cells modified with a conjugate that are useful for generating or enhancing an immune response to an antigen or infectious agent. The invention also provides immunostimulatory moieties comprising an immune co-stimulatory polypeptide that are useful for stimulating an immune response. The invention also provides immunotherapy methods and methods of treating or preventing infections.
    Type: Grant
    Filed: December 7, 2006
    Date of Patent: October 6, 2009
    Assignee: University of Louisville Research Foundation, Inc.
    Inventors: Haval Shirwan, Kutlu G. Elpek, Esma S. Yolcu