Abstract: The present invention relates to an in-vivo bulking agent which can be used as a medicinal agent for prevention or treatment of at least one disease selected from the group consisting of urinary incontinence, fecal incontinence, and gastroesophageal reflux or as a filler for use in a plastic surgery procedure, and to a preparation method therefor. The in-vivo bulking agent can exhibit a bulking effect when injected into the body and particularly, is highly biocompatible because a first composition in which silicone particles are coated with a zwitterionic polymer having a surfactant property is introduced into a second composition, whereby the bulking agent can inhibit inflammatory reactions in vivo.

Abstract: The present invention relates to a device for measuring a bodily fluid drainage amount, the device comprising: a measurement case which is formed of a rigid material and provided with a bodily fluid measurement space therein; a drainage tube which is coupled to an entrance of the measurement case in a releasable structure and transfers bodily fluids discharged from a human body to the bodily fluid measurement space of the measurement case; a plurality of fluid level sensors, which are horizontally disposed on an upper surface of the measurement case and measure and inform fluid levels of the bodily fluids collected in the bodily fluid measurement space; and a control device which receives and analyzes the fluid levels of the bodily fluids, infers a tilt of the measurement case from a difference in the fluid levels of the bodily fluids, and calculates and informs a bodily fluid drainage amount.

Abstract: The present invention relates to an in-vivo bulking agent which can be used as a medicinal agent for prevention or treatment of at least one disease selected from the group consisting of urinary incontinence, fecal incontinence, and gastroesophageal reflux or as a filler for use in a plastic surgery procedure, and to a preparation method therefor. The in-vivo bulking agent can exhibit a bulking effect when injected into the body and particularly, is highly biocompatible because a first composition in which silicone particles are coated with a zwitterionic polymer having a surfactant property is introduced into a second composition, whereby the bulking agent can inhibit inflammatory reactions in vivo.