Abstract: Disclosed are a metal-nanoparticle-based liver-specific nucleic acid delivery system, a method of manufacturing the same, and a liver disease treatment composition containing the same. The liver-specific nucleic acid delivery system is coated with a bile acid-glycol chitosan polymer, so that it provides excellent liver-tissue specificity and high absorbance through digestive canals. Since the nucleic acid of the nucleic acid delivery system is coated with the bile acid-glycol chitosan polymer, it can be protected from decomposition of enzymes and the like inside a living organism. The liver-specific nucleic acid delivery system can be developed as an oral-administrating liver-disease treatment.

Abstract: Disclosed are a metal-nanoparticle-based liver-specific nucleic acid delivery system, a method of manufacturing the same, and a liver disease treatment composition containing the same. The liver-specific nucleic acid delivery system is coated with a bile acid-glycol chitosan polymer, so that it provides excellent liver-tissue specificity and high absorbance through digestive canals. Since the nucleic acid of the nucleic acid delivery system is coated with the bile acid-glycol chitosan polymer, it can be protected from decomposition of enzymes and the like inside a living organism. The liver-specific nucleic acid delivery system can be developed as an oral-administrating liver-disease treatment.

Abstract: The present invention relates to an antenna for a cellular phone that is always installed in the same construction irrespective of an outer look of an antenna when the antenna is engaged to a cellular phone body, and is stably fixed to a cellular phone body, and an assembling and disassembling procedure are easy, and an antenna exchanging operation is conveniently performed. The antenna for a cellular phone comprises an antenna holder having a guide groove part and engaged in a body of a cellular phone; an antenna housing that is formed of an antenna connector having a protrusion part engaged to the guide groove part and fixedly inserted into the antenna holder, and an antenna support part integrally formed in the antenna connector; and a rod antenna that passes through the antenna connector and the antenna support part, respectively, in such a manner that the rod antenna is extendable from the body of the cellular phone.

Abstract: The invention relates to pyrimidinone derivatives and the pharmaceutically acceptable salts thereof having remarkable antagonistic action against angiotensin II receptor, and thus useful in treating cardiovascular diseases caused by angiotensin II.