Abstract: The present invention relates to an antigen-binding molecule comprising a heavy chain variable region comprising a heavy-chain complementarity-determining region 1 (HCDR1) comprising an amino acid sequence represented by Sequence No. 1, an HCDR2 comprising an amino acid sequence represented by Sequence No. 2, and an HCDR3 comprising an amino acid sequence represented by Sequence No. 3; a light-chain variable region comprising a light-chain complementarity-determining region 1 (LCDR1) comprising an amino acid sequence represented by Sequence No. 4, an LCDR2 comprising an amino acid sequence represented by Sequence No. 5, and an LCDR3 comprising an amino acid sequence represented by Sequence No. 6; wherein the antigen-binding molecule is a T cell receptor (TCR); and to a cell line expressing the same.

Abstract: A system for cutting a three-dimensional portion from a foodstuff includes a conveyor for carrying a foodstuff to be portioned, a scanner located adjacent to the conveyor for scanning the foodstuff, a computer coupled to the scanner for receiving scan information to determine one or more cutting paths for the foodstuff, and a cutter for portioning the foodstuff according to the determined cutting path(s). The computer performs generally four steps: (i) receiving scan information from the scanner; (ii) building a three-dimensional map of the foodstuff based on the received scan information; (iii) fitting at least one desired shape, which is stored in the memory of the computer, onto the built three-dimensional map; and (iv) determining one or more cutting paths for portioning the foodstuff to produce one or more portioned foodstuffs corresponding to the at least one desired shape.

Abstract: The invention is directed to methods of treating organ specific infections in a host organism by administering compounds that target host receptors and/or host cellular signaling molecules to prevent a pathogen from infecting the organ. For example, the administration of a compound to prevent a pathogen from crossing the blood-brain barrier to prevent a brain infection.

Abstract: The present invention relates to methods and compositions for the treatment of bacterial infection, for example extraintestinal E. coli infection such as E. coli bacteremia, meningitis and sepsis. The invention relates also to methods of diagnosis and prevention.

Abstract: A rare earth doped optical fiber amplifier is configured to have an enlarged core region and a trench formed adjacent to the core, where at least an inner portion of the trench is also formed to include a rare earth dopant. The presence of the rare earth dopant in the inner region of the cladding minimizes transient power fluctuations within the amplifier as the number of optical signals being amplified changes. The addition of rare earth dopant to the cladding increases the overlap between the pump, signal and the rare earth ions and thus improves the gain efficiency for the optical signal. The relatively large core diameter increases the saturation power level of the rare earth dopant and decreases the transients present in the gain as the input signal power fluctuates.

Abstract: The invention is directed to methods of treating organ specific infections in a host organism by administering compounds that target host receptors and/or host cellular signaling molecules to prevent a pathogen from infecting the organ. For example, the administration of a compound to prevent a pathogen from crossing the blood-brain barrier to prevent a brain infection.

Abstract: A rare earth doped optical fiber amplifier is configured to have an enlarged core region and a trench formed adjacent to the core, where at least an inner portion of the trench is also formed to include a rare earth dopant. The presence of the rare earth dopant in the inner region of the cladding minimizes transient power fluctuations within the amplifier as the number of optical signals being amplified changes. The addition of rare earth dopant to the cladding increases the overlap between the pump, signal and the rare earth ions and thus improves the gain efficiency for the optical signal. The relatively large core diameter increases the saturation power level of the rare earth dopant and decreases the transients present in the gain as the input signal power fluctuates.

Abstract: Ultralong carbon nanotubes can be formed by placing a secondary chamber within a reactor chamber to restrict a flow to provide a laminar flow. Inner shells can be successively extracted from multi-walled carbon nanotubes (MWNTs) such as by applying a lateral force to an elongated tubular sidewall at a location between its two ends. The extracted shells can have varying electrical and mechanical properties that can be used to create useful materials, electrical devices, and mechanical devices.

Abstract: A system for cutting a three-dimensional portion from a foodstuff. The system includes a scanner for scanning the foodstuff, a computer coupled to the scanner for receiving information from the scanner to determine one or more cutting paths for the foodstuff, and a cutter for portioning the foodstuff according to the one or more determined cutting paths. The computer is configured to perform generally four steps: (i) receiving scan information of the foodstuff from the scanner; (ii) building a three-dimensional map of the foodstuff based on the received scan information of the foodstuff; (iii) fitting at least one desired shape, which is stored in memory of the computer, onto the three-dimensional map in the memory of the computer; and (iv) determining one or more cutting paths to be used in portioning the foodstuff so as to produce one or more portioned foodstuffs corresponding to the at least one desired shape.

Abstract: Ultralong carbon nanotubes can be formed by placing a secondary chamber within a reactor chamber to restrict a flow to provide a laminar flow. Inner shells can be successively extracted from multi-walled carbon nanotubes (MWNTs) such as by applying a lateral force to an elongated tubular sidewall at a location between its two ends. The extracted shells can have varying electrical and mechanical properties that can be used to create useful materials, electrical devices, and mechanical devices.

Abstract: A system is provided for cutting a three-dimensional portion from a foodstuff. The system includes a conveyor for carrying a foodstuff to be portioned, a scanner located adjacent to the conveyor for scanning the foodstuff, a computer coupled to the scanner for receiving scan information from the scanner to determine one or more cutting paths for the foodstuff, and a cutter for portioning the foodstuff according to the one or more determined cutting paths.

Abstract: Ultralong carbon nanotubes can be formed by placing a secondary chamber within a reactor chamber to restrict a flow to provide a laminar flow. Inner shells can be successively extracted from multi-walled carbon nanotubes (MWNTs) such as by applying a lateral force to an elongated tubular sidewall at a location between its two ends. The extracted shells can have varying electrical and mechanical properties that can be used to create useful materials, electrical devices, and mechanical devices.

Abstract: The portioning foodstuffs in three dimensions includes generating a three-dimensional map of the foodstuff, and then comparing the generated three-dimensional map of the foodstuff with the desired shape as stored in the memory of a computer. The computer determines the particular cutting path in three dimensions in order to arrive at the predetermined shape. This is followed by cutting in one direction to fix at least one dimension of the foodstuff, determining whether the foodstuff is within the tolerance limits or whether the foodstuff portion has moved during the first cutting operation. If so, the foodstuff is rescanned to generate a two-dimensional image of the foodstuff, followed by cutting the foodstuff to arrive at a portion trimmed along three dimensions.

Abstract: A method for portioning foodstuffs in three dimensions includes scanning the foodstuff to be portion, generating a three-dimensional map of the foodstuff, then comparing the generated three-dimensional map of the foodstuff with the desired shape which is stored in the memory of a computer. A computer then determines a particular cutting path in three dimensions in order to arrive at the predetermined shape, followed by a cutting in one direction to fix at least one dimension of the foodstuff, then determining whether the foodstuff is within the tolerance limits. The foodstuff is thereafter cut along its other dimensions to arrive at a portion trimmed along three dimensions.

Abstract: The present invention relates to methods and compositions for the treatment of bacterial infection, for example extraintestinal E. coli infection such as E. coli bacteremia, meningitis and sepsis. The invention relates also to methods of diagnosis and prevention.

Abstract: Electrolysis cell comprises, in one embodiment, a proton exchange membrane (PEM), an anode positioned along one face of the PEM, and a cathode positioned along the other face of the PEM. An electrically-conductive, compressible, spring-like, porous pad for defining a fluid cavity is placed in contact with the outer face of the cathode. The porous pad comprises a mat of carbon fibers bound together with one or more, preferably thermoplastic, resins, the mat having a density of about 0.2-1.5 g/cm3. Cell frames are placed in peripheral contact with the metal screen and the compression pad for peripherally containing fluids present therewithin. Electrically-conductive separators are placed in contact with the metal screen and the compression pad for axially containing fluids present therewithin. A plurality of the cells may be arranged in series in a bipolar configuration without requiring a separate compression pad between cells (for gas pressure differentials up to about 400 psi or greater).

Abstract: Ultralong carbon nanotubes can be formed by placing a secondary chamber within a reactor chamber to restrict a flow to provide a laminar flow. Inner shells can be successively extracted from multi-walled carbon nanotubes (MWNTs) such as by applying a lateral force to an elongated tubular sidewall at a location between its two ends. The extracted shells can have varying electrical and mechanical properties that can be used to create useful materials, electrical devices, and mechanical devices.

Abstract: Electrolysis cell comprises, in one embodiment, a proton exchange membrane (PEM), an anode positioned along one face of the PEM, and a cathode positioned along the other face of the PEM. An electrically-conductive, compressible, spring-like, porous pad for defining a fluid cavity is placed in contact with the outer face of the cathode. The porous pad comprises a mat of carbon fibers bound together with one or more, preferably thermoplastic, resins, the mat having a density of about 0.2-1.5 g/cm3. Cell frames are placed in peripheral contact with the metal screen and the compression pad for peripherally containing fluids present therewithin. Electrically-conductive separators are placed in contact with the metal screen and the compression pad for axially containing fluids present therewithin. A plurality of the cells may be arranged in series in a bipolar configuration without requiring a separate compression pad between cells (for gas pressure differentials up to about 400 psi or greater).

Abstract: A system is provided for cutting a three-dimensional portion from a foodstuff. The system includes a conveyor for carrying a foodstuff to be portioned, a scanner located adjacent to the conveyor for scanning the foodstuff, a computer coupled to the scanner for receiving scan information from the scanner to determine one or more cutting paths for the foodstuff, and a cutter for portioning the foodstuff according to the one or more determined cutting paths.

Abstract: Electrolysis cell comprises, in one embodiment, a proton exchange membrane (PEM), an anode positioned along one face of the PEM, and a cathode positioned along the other face of the PEM. A multi-layer metal screen for defining a first fluid cavity is placed in contact with the outer face of the anode, and an electrically-conductive, compressible, spring-like, porous pad for defining a second fluid cavity is placed in contact with the outer face of the cathode. The porous pad comprises a mat of carbon fibers bound together with one or more, preferably thermoplastic, resins, the mat having a density of about 0.2-1.5 g/cm3. Cell frames are placed in peripheral contact with the metal screen and the compression pad for peripherally containing fluids present therewithin. Electrically-conductive separators are placed in contact with the metal screen and the compression pad for axially containing fluids present therewithin.