Patents by Inventor KWEI-YU LIU

KWEI-YU LIU has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11878088
    Abstract: The invention includes chitosan nanofibers having enhanced structural integrity, compositions comprising such chitosan nanofibers, and related methods of use. In a particular aspect, electrospun chitosan nanofibers can be reversibly acylated to enhance structural integrity and promote healing and the formation of tissues in a subject. In another aspect, electrospun chitosan nanofibers comprising at least a portion of the amino groups protected, such as through N-tert-butoxycarbonyl groups, demonstrate enhanced structural integrity and promote healing and the formation of tissues in a subject. The invention also includes compositions and methods for producing a modified chitosan material having anti-inflammatory and pro-healing characteristics and methods of using the modified chitosan materials in a film, a gel, a membrane, microfibers, nanofibers, nano- or micro-particles/spheres and/or sponges. In some aspects, microspheres and methods of producing microspheres comprising modified chitosan are included.
    Type: Grant
    Filed: December 1, 2021
    Date of Patent: January 23, 2024
    Assignee: The University of Memphis Research Foundation
    Inventors: Joel D. Bumgardner, Hengjie Su, Tomoko Fujiwara, Daniel G. Abebe, Kwei-Yu Liu
  • Publication number: 20220160935
    Abstract: The invention includes chitosan nanofibers having enhanced structural integrity, compositions comprising such chitosan nanofibers, and related methods of use. In a particular aspect, electrospun chitosan nanofibers can be reversibly acylated to enhance structural integrity and promote healing and the formation of tissues in a subject. In another aspect, electrospun chitosan nanofibers comprising at least a portion of the amino groups protected, such as through N-tert-butoxycarbonyl groups, demonstrate enhanced structural integrity and promote healing and the formation of tissues in a subject. The invention also includes compositions and methods for producing a modified chitosan material having anti-inflammatory and pro-healing characteristics and methods of using the modified chitosan materials in a film, a gel, a membrane, microfibers, nanofibers, nano- or micro-particles/spheres and/or sponges. In some aspects, microspheres and methods of producing microspheres comprising modified chitosan are included.
    Type: Application
    Filed: December 1, 2021
    Publication date: May 26, 2022
    Applicant: The University of Memphis Research Foundation
    Inventors: Joel D. Bumgardner, Hengjie Su, Tomoko Fujiwara, Daniel G. Abebe, Kwei-Yu Liu
  • Patent number: 11229721
    Abstract: The invention includes chitosan nanofibers having enhanced structural integrity, compositions comprising such chitosan nanofibers, and related methods of use. In a particular aspect, electrospun chitosan nanofibers can be reversibly acylated to enhance structural integrity and promote healing and the formation of tissues in a subject. In another aspect, electrospun chitosan nanofibers comprising at least a portion of the amino groups protected, such as through N-tert-butoxycarbonyl groups, demonstrate enhanced structural integrity and promote healing and the formation of tissues in a subject. The invention also includes compositions and methods for producing a modified chitosan material having anti-inflammatory and pro-healing characteristics and methods of using the modified chitosan materials in a film, a gel, a membrane, microfibers, nanofibers, nano- or micro-particles/spheres and/or sponges. In some aspects, microspheres and methods of producing microspheres comprising modified chitosan are included.
    Type: Grant
    Filed: February 27, 2015
    Date of Patent: January 25, 2022
    Assignee: THE UNIVERSITY OF MEMPHIS RESEARCH FOUNDATION
    Inventors: Joel D. Bumgardner, Chaoxi Wu, Hengjie Su, Tomoko Fujiwara, Daniel G. Abebe, Kwei-Yu Liu, Gregory McGraw, Carlos Lee Bumgardner
  • Publication number: 20160367722
    Abstract: The invention includes chitosan nanofibers having enhanced structural integrity, compositions comprising such chitosan nanofibers, and related methods of use. In a particular aspect, electrospun chitosan nanofibers can be reversibly acylated to enhance structural integrity and promote healing and the formation of tissues in a subject. In another aspect, electrospun chitosan nanofibers comprising at least a portion of the amino groups protected, such as through N-tert-butoxycarbonyl groups, demonstrate enhanced structural integrity and promote healing and the formation of tissues in a subject. The invention also includes compositions and methods for producing a modified chitosan material having anti-inflammatory and pro-healing characteristics and methods of using the modified chitosan materials in a film, a gel, a membrane, microfibers, nanofibers, nano- or micro-particles/spheres and/or sponges. In some aspects, microspheres and methods of producing microspheres comprising modified chitosan are included.
    Type: Application
    Filed: February 27, 2015
    Publication date: December 22, 2016
    Applicant: THE UNIVERSITY OF MEMPHIS RESEARCH FOUNDATION
    Inventors: JOEL D. BUMGARDNER, CHAOXI WU, HENGJIE SU, TOMOKO FUJIWARA, DANIEL G. ABEBE, KWEI-YU LIU, GREGORY MCGRAW, CARLOS LEE BUMGARDNER