Patents by Inventor Kwonsoo Chun

Kwonsoo Chun has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11464632
    Abstract: Some embodiments are directed to a transcatheter and serially-expandable artificial heart valve, e.g., to be minimally-invasively implanted into a pediatric patient during a first procedure, and then expanded during a second procedure to accommodate for the pediatric patient's growth. Some embodiments include an expandable frame having a compressed, delivery configuration, and an expanded, deployed configuration, in which the valve is implantable within the patient. The valve can have a first working condition when the frame is expanded to a first diameter and a second working condition when the frame is expanded to a second diameter greater than the first diameter. The valve can include a plurality of leaflets configured to accommodate the expansion of the frame and growth of the patient.
    Type: Grant
    Filed: September 13, 2021
    Date of Patent: October 11, 2022
    Assignees: Baylor College of Medicine, William Marsh Rice University
    Inventors: Henri Justino, Daniel Harrington, Kwonsoo Chun
  • Publication number: 20220125581
    Abstract: Some embodiments are directed to methods for serially expanding an artificial heart valve within a pediatric patient. For example, the artificial heart valve can be implanted into the pediatric patient during a first procedure, and then expanded during a second procedure to accommodate for the pediatric patient's growth. Some embodiments include introducing an expander into the implanted valve when the frame is expanded to a first working diameter, and then actuating the expander to expand the frame to a second working diameter greater than the first working diameter, to accommodate for the pediatric patient's growth.
    Type: Application
    Filed: September 17, 2021
    Publication date: April 28, 2022
    Applicants: Baylor College of Medicine, William Marsh Rice University
    Inventors: Henri JUSTINO, Daniel HARRINGTON, Kwonsoo CHUN
  • Publication number: 20220117731
    Abstract: Some embodiments are directed to a transcatheter and serially-expandable artificial heart valve, e.g., to be minimally-invasively implanted into a pediatric patient during a first procedure, and then expanded during a second procedure to accommodate for the pediatric patient's growth. Some embodiments include an expandable frame having a compressed, delivery configuration, and an expanded, deployed configuration, in which the valve is implantable within the patient. The valve can have a first working condition when the frame is expanded to a first diameter and a second working condition when the frame is expanded to a second diameter greater than the first diameter. The valve can include a plurality of leaflets configured to accommodate the expansion of the frame and growth of the patient.
    Type: Application
    Filed: September 13, 2021
    Publication date: April 21, 2022
    Applicants: Baylor College of Medicine, William Marsh Rice University
    Inventors: Henri JUSTINO, Daniel HARRINGTON, Kwonsoo CHUN
  • Publication number: 20200000581
    Abstract: One aspect of the invention provides and artificial, flexible valve indlucding: a stent defining a wall and a plurality of leaflets extending from the wall of the stent. The plurality of leaflets form a plurality of coaptation regions between two adjacent leaflets. The coaptation regions include extensions along a z-axis and adapted and are configured to form a releasable, but substantially complete seal when the leaflets are in a closed position. Another aspect of the invention provides an artificial, flexible valve including: a stent defining a wall and a plurality of leaflets extending from the wall of the stent. Each of the plurality of leaflets terminates in a commissure line. The commissure lines devi-ate from a hyperbola formed in the x-y plane by at least one deviation selected from the group consisting of: a deviation in the z-direction and one or more curves relative to the hyperbola.
    Type: Application
    Filed: September 6, 2019
    Publication date: January 2, 2020
    Applicants: Baylor College of Medicine, William Marsh Rice University
    Inventors: Henri JUSTINO, Daniel HARRINGTON, Kwonsoo CHUN
  • Patent number: 10106278
    Abstract: An automated system (100) for compounding pharmaceutical agents for injection treatment of a patient includes a housing (110) enclosing an interior space; an inventory structure (130) having a plurality of chambers (131) for individually holding one or more pharmaceutical agent—containing single use capsules (102), wherein each capsule has a volume capacity of from about 0.1 to about 10.0 mL liquid; means (140) for selecting capsules in accordance with predetermined pharmaceutical agents contained in said capsules; means (150) for moving the selected capsules to a processing area; means (165,166) for sequentially transferring a controlled quantity of the predetermined pharmaceutical agent with direct fluid communication from each selected capsule to a product container under positive or negative pressure; and means (151) for automatically discarding spent capsules from which the pharmaceutical agents have been removed after a single use.
    Type: Grant
    Filed: December 9, 2015
    Date of Patent: October 23, 2018
    Assignee: Aquavit Pharmaceuticals, Inc.
    Inventors: Sobin Chang, Kwonsoo Chun
  • Publication number: 20170189175
    Abstract: One aspect of the invention provides an artificial, flexible valve including: a stent defining a wall and a plurality of leaflets extending from the wall of the stent. The plurality of leaflets form a plurality of coaptation regions between two adjacent leaflets. The coaptation regions include extensions along a z-axis and adapted and are configured to form a releasable, but substantially complete seal when the leaflets are in a closed position. Another aspect of the invention provides an artificial, flexible valve including: a stent defining a wall and a plurality of leaflets extending from the wall of the stent. Each of the plurality of leaflets terminates in a commissure line. The commissure lines deviate from a hyperbola formed in the x-y plane by at least one deviation selected from the group consisting of: a deviation in the z-direction and one or more curves relative to the hyperbola.
    Type: Application
    Filed: May 6, 2015
    Publication date: July 6, 2017
    Applicants: Baylor College of Medicine, William Marsh Rice University
    Inventors: Henri Justino, Daniel Harrington, Kwonsoo Chun
  • Patent number: 9675519
    Abstract: An automated system (100) for compounding pharmaceutical agents for injection treatment of a patient includes a housing (110) enclosing an interior space; an inventory structure (130) having a plurality of chambers (131) for individually holding one or more pharmaceutical agent—containing single use capsules (102), wherein each capsule has a volume capacity of from about 0.1 to about 10.0 mL liquid; means (140) for selecting capsules in accordance with predetermined pharmaceutical agents contained in said capsules; means (150) for moving the selected capsules to a processing area; means (165,166) for sequentially transferring a controlled quantity of the predetermined pharmaceutical agent with direct fluid communication from each selected capsule to a product container under positive or negative pressure; and means (151) for automatically discarding spent capsules from which the pharmaceutical agents have been removed after a single use.
    Type: Grant
    Filed: January 27, 2012
    Date of Patent: June 13, 2017
    Assignee: Aquavit Pharmaceuticals, Inc.
    Inventors: Sobin Chang, Kwonsoo Chun
  • Publication number: 20160089301
    Abstract: An automated system (100) for compounding pharmaceutical agents for injection treatment of a patient includes a housing (110) enclosing an interior space; an inventory structure (130) having a plurality of chambers (131) for individually holding one or more pharmaceutical agent—containing single use capsules (102), wherein each capsule has a volume capacity of from about 0.1 to about 10.0 mL liquid; means (140) for selecting capsules in accordance with predetermined pharmaceutical agents contained in said capsules; means (150) for moving the selected capsules to a processing area; means (165,166) for sequentially transferring a controlled quantity of the predetermined pharmaceutical agent with direct fluid communication from each selected capsule to a product container under positive or negative pressure; and means (151) for automatically discarding spent capsules from which the pharmaceutical agents have been removed after a single use.
    Type: Application
    Filed: December 9, 2015
    Publication date: March 31, 2016
    Inventors: Sobin Chang, Kwonsoo Chun
  • Publication number: 20150034208
    Abstract: An automated system (100) for compounding pharmaceutical agents for injection treatment of a patient includes a housing (110) enclosing an interior space; an inventory structure (130) having a plurality of chambers (131) for individually holding one or more pharmaceutical agent—containing single use capsules (102), wherein each capsule has a volume capacity of from about 0.1 to about 10.0 mL liquid; means (140) for selecting capsules in accordance with predetermined pharmaceutical agents contained in said capsules; means (150) for moving the selected capsules to a processing area; means (165,166) for sequentially transferring a controlled quantity of the predetermined pharmaceutical agent with direct fluid communication from each selected capsule to a product container under positive or negative pressure; and means (151) for automatically discarding spent capsules from which the pharmaceutical agents have been removed after a single use.
    Type: Application
    Filed: January 27, 2012
    Publication date: February 5, 2015
    Inventors: Sobin Chang, Kwonsoo Chun
  • Publication number: 20050129162
    Abstract: A system and method for producing 18F-Fluroide by using a proton beam to irradiate 180xygen in gasous form. The irradiated 180xygen is contained in a chamber that includes at least one component to which the produced 18F-Fluoride adheres. A solvent dissolves the produced 18F-Fluoride off of the at least one component while it is in the chjamber. The solvent is then processed to obtain the 18F-Fluoride.
    Type: Application
    Filed: November 19, 2004
    Publication date: June 16, 2005
    Inventors: Thomas Ruth, Kenneth Buckley, Kwonsoo Chun, Salma Jivan, Stefan Zeisler
  • Patent number: 6845137
    Abstract: A system and method for producing 18F-Fluoride by using a proton beam to irradiate 18Oxygen in gaseous form. The irradiated 18Oxygen is contained in a chamber that includes at least one component to which the produced 18F-Fluoride adheres. A solvent dissolves the produced 18F-Fluoride off of the at least one component while it is in the chamber. The solvent is then processed to obtain the 18F-Fluoride.
    Type: Grant
    Filed: February 23, 2001
    Date of Patent: January 18, 2005
    Assignee: Triumf
    Inventors: Thomas J. Ruth, Kenneth R. Buckley, Kwonsoo Chun, Salma Jivan, Stefan K. Zeisler
  • Publication number: 20010043663
    Abstract: A system and method for producing 18F-Fluoride by using a proton beam to irradiate 18Oxygen in gaseous form. The irradiated 18Oxygen is contained in a chamber that includes at least one component to which the produced 18F-Fluoride adheres. A solvent dissolves the produced 18F-Fluoride off of the at least one component while it is in the chamber. The solvent is then processed to obtain the 18F-Fluoride.
    Type: Application
    Filed: February 23, 2001
    Publication date: November 22, 2001
    Inventors: Thomas J. Ruth, Kenneth R. Buckley, Kwonsoo Chun, Salma Jivan, Stefan K. Zeisler