Abstract: Systems and method for performing simultaneous optical coherence tomography and spectroscopy. In one embodiment, a system includes a light source that emits light to be delivered to a material under evaluation, and a receiver that collects both light that is backscattered by features of the material and fluorescent light that is emitted by features of the material. In one embodiment, a method includes simultaneously collecting near-infrared light backscattered by a material under evaluation and fluorescent light emitted by the material under evaluation using a single light detector.

Abstract: Disclosed are optical probes and methods for use of such probes. In one embodiment, an optical probe includes a housing that is sized and configured to be passed through a lumen having an inner diameter no greater than approximately 2 millimeters, and an internal optical system provided within the housing, the optical system being configured to capture images of a feature of interest associated with the lumen. In another embodiment, an optical probe includes a housing configured for passage through a narrow lumen, and an internal optical system provided within the housing that is configured to capture images of a feature of interest associated with the lumen, the optical system including axicon optics that form a focal line rather than a discrete focal point.