Patents by Inventor Kye Wan Lee

Kye Wan Lee has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • PHARMACEUTICAL COMPOSITION COMPRISING TADALAFIL OR PHARMACEUTICALLLY ACCEPTABLE SALT THEREOF AND DUTASTERIDE OR PHARMACEUTICALLLY ACCEPTABLE SALT THEREOF EXHIBITING NOVEL DISSOLUTION RATE
    Publication number: 20240075028
    Abstract: Provided is a pharmaceutical composition comprising as active ingredients: 5 mg of tadalafil or a pharmaceutically acceptable salt thereof; and 0.5 mg of dutasteride or a pharmaceutically acceptable salt thereof, wherein the dissolution rate of tadalafil under the dissolution conditions of a paddle rate of 50 rpm in 500 mL of a dissolution solution having a pH of 1.2 and containing 0.25% of SLS is 60-75% after 5 minutes and 80% or more after 30 minutes, and the dissolution rate of dutasteride under the dissolution conditions of a paddle rate of 50 rpm in 500 mL of a dissolution solution containing water and 0.1% of SLS is 50% or more after 15 minutes and 85% or more after 30 minutes.
    Type: Application
    Filed: December 30, 2021
    Publication date: March 7, 2024
    Inventors: Ye Ri LEE, Sung Hoon JUN, Jong Sil KIM, Kye Wan LEE
  • Pharmaceutical composition containing avocado oil fraction as active ingredient for prevention or treatment of hearing loss
    Patent number: 11273194
    Abstract: The present invention relates to a pharmaceutical composition containing an avocado oil fraction as an active ingredient for prevention or treatment of hearing loss. Specifically, the avocado oil fraction according to the present invention, especially, an isopropanol fraction of avocado oil significantly increases the number of hair cells reduced by neomycin in zebrafish models, so the isopropanol fraction of avocado oil can be favorably used in the treatment of hearing loss.
    Type: Grant
    Filed: February 14, 2020
    Date of Patent: March 15, 2022
    Assignee: DONG KOOK PHARM CO., LTD
    Inventors: Bin Na Hong, Woo Jae Jung, Kye Wan Lee, Jung Suk Lee, Yu Hwa Park, Do Hoon Kim
  • PHARMACEUTICAL COMPOSITION CONTAINING AVOCADO OIL FRACTION AS ACTIVE INGREDIENT FOR PREVENTION OR TREATMENT OF HEARING LOSS
    Publication number: 20200215142
    Abstract: The present invention relates to a pharmaceutical composition containing an avocado oil fraction as an active ingredient for prevention or treatment of hearing loss. Specifically, the avocado oil fraction according to the present invention, especially, an isopropanol fraction of avocado oil significantly increases the number of hair cells reduced by neomycin in zebrafish models, so the isopropanol fraction of avocado oil can be favorably used in the treatment of hearing loss.
    Type: Application
    Filed: February 14, 2020
    Publication date: July 9, 2020
    Applicant: DONG KOOK PHARM CO., LTD
    Inventors: Bin Na Hong, Woo Jae Jung, Kye Wan Lee, Jung Suk Lee, Yu Hwa Park, Do Hoon Kim
  • variant and method for producing daptomycin using same
    Patent number: 10301690
    Abstract: Provided are a novel streptomyces filamentosus strain with improved daptomycin productivity, and a method for producing daptomycin using the same.
    Type: Grant
    Filed: December 17, 2014
    Date of Patent: May 28, 2019
    Assignee: DONG KOOK PHARM CO., LTD.
    Inventors: Kang Hee Lee, Kye Wan Lee, Kyung Hoi Cha
  • NEW STREPTOMYCES FILAMENTOSUS VARIANT AND METHOD FOR PRODUCING DAPTOMYCIN USING SAME
    Publication number: 20170037484
    Abstract: Provided are a novel streptomyces filamentosus strain with improved daptomycin productivity, and a method for producing daptomycin using the same.
    Type: Application
    Filed: December 17, 2014
    Publication date: February 9, 2017
    Inventors: Kang Hee Lee, Kye Wan Lee, Kyung Hoi Cha