Patents by Inventor Kyeong Sook CHOI

Kyeong Sook CHOI has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Pharmaceutical composition for preventing or treating cancer, containing proteasome inhibitor and loperamide as active ingredients
    Patent number: 9931331
    Abstract: The present invention relates to an anticancer supplement containing loperamide as an active ingredient. More specifically, a proteasome inhibitor alone cannot exhibit an anticancer effect on solid cancers and some blood cancers, but when the proteasome inhibitor and loperamide are co-administered or a composition containing the proteasome inhibitor and loperamide is provided, cancer cell death by the proteasome inhibitor can be effectively induced, thereby exhibiting an improved anticancer effect, and enhancing anticancer effects on solid cancers and blood cancers while reducing side effects caused by a high-concentration of the proteasome inhibitor. Therefore, the composition containing the proteasome inhibitor and loperamide as active ingredients, according to the present invention, can be useful for preventing or treating cancer, and loperamide can be provided as an anticancer supplement when the proteasome inhibitor is used to treat cancer.
    Type: Grant
    Filed: September 17, 2014
    Date of Patent: April 3, 2018
    Assignee: AJOU UNIVERSITY INDUSTRY-ACADEMIC COOPERATION FOUN DATION
    Inventors: Kyeong Sook Choi, In Young Kim, Mi Jin Yoon, A Reum Lee
  • PHARMARCEUTICAL COMPOSITION FOR PREVENTING OR TREATING CANCER, CONTAINING PROTEASOME INHIBITOR AND LOPERAMIDE AS ACTIVE INGREDIENTS
    Publication number: 20160324843
    Abstract: The present invention relates to an anticancer supplement containing loperamide as an active ingredient. More specifically, a proteasome inhibitor alone cannot exhibit an anticancer effect on solid cancers and some blood cancers, but when the proteasome inhibitor and loperamide are co-administered or a composition containing the proteasome inhibitor and loperamide is provided, cancer cell death by the proteasome inhibitor can be effectively induced, thereby exhibiting an improved anticancer effect, and enhancing anticancer effects on solid cancers and blood cancers while reducing side effects caused by a high-concentration of the proteasome inhibitor. Therefore, the composition containing the proteasome inhibitor and loperamide as active ingredients, according to the present invention, can be useful for preventing or treating cancer, and loperamide can be provided as an anticancer supplement when the proteasome inhibitor is used to treat cancer.
    Type: Application
    Filed: September 17, 2014
    Publication date: November 10, 2016
    Applicant: AJOU UNIVERSITY INDUSTRY-ACADEMIC COOPERATION FOUN DATION
    Inventors: Kyeong Sook CHOI, In Young KIM, Mi Jin YOON, A Reum LEE